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Additional file 6: Figure S3. of Classification of low quality cells from single-cell RNA-seq data

Autor: Ilicic, Tomislav, Kim, Jong, Kolodziejczyk, Aleksandra, Bagger, Frederik, McCarthy, Davis, Marioni, John, Teichmann, Sarah

Post-QC outliers and SVM performance evaluation. (A) Visualization of low and high quality cells after outlier detection with traditional and with our PCA feature-based methods (B) Schematic of nested cross-validation. The training set was split twic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2001821c4e1f6e6642758368c9846f09

Additional file 7: Figure S4. of Classification of low quality cells from single-cell RNA-seq data

Autor: Ilicic, Tomislav, Kim, Jong, Kolodziejczyk, Aleksandra, Bagger, Frederik, McCarthy, Davis, Marioni, John, Teichmann, Sarah

Datasets distant from mES training data. (A) Comparing log normalized UMI counts (y-axis) and log normalized read counts (x-axis) for each gene in 960 mESCs. (B) PCA of first two principal components of all features. Low quality cells separate from h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5fcd215da4463dc0acf5b243dc47db3e

Signatures of mutational processes in human cancer

Autor: Alexandrov, Ludmil B, Nik-Zainal, Serena, Wedge, David C, Aparicio, Samuel AJR, Behjati, Sam, Biankin, Andrew V, Bignell, Graham R, Bolli, Niccolò, Borg, Ake, Børresen-Dale, Anne-Lise, Boyault, Sandrine, Burkhardt, Birgit, Butler, Adam P, Caldas, Carlos, Davies, Helen R, Desmedt, Christine, Eils, Roland, Eyfjörd, Jórunn Erla, Foekens, John A, Greaves, Mel, Hosoda, Fumie, Hutter, Barbara, Ilicic, Tomislav, Imbeaud, Sandrine, Imielinski, Marcin, Jäger, Natalie, Jones, David TW, Jones, David, Knappskog, Stian, Kool, Marcel, Lakhani, Sunil R, López-Otín, Carlos, Martin, Sancha, Munshi, Nikhil C, Nakamura, Hiromi, Northcott, Paul A, Pajic, Marina, Papaemmanuil, Elli, Paradiso, Angelo, Pearson, John V, Puente, Xose S, Raine, Keiran, Ramakrishna, Manasa, Richardson, Andrea L, Richter, Julia, Rosenstiel, Philip, Schlesner, Matthias, Schumacher, Ton N, Span, Paul N, Teague, Jon W, Totoki, Yasushi, Tutt, Andrew NJ, Valdés-Mas, Rafael, van Buuren, Marit M, van 't Veer, Laura, Vincent-Salomon, Anne, Waddell, Nicola, Yates, Lucy R, Australian Pancreatic Cancer Genome Initiative, ICGC Breast Cancer Consortium, ICGC MMML-Seq Consortium, ICGC PedBrain, Zucman-Rossi, Jessica, Futreal, P Andrew, McDermott, Ultan, Lichter, Peter, Meyerson, Matthew, Grimmond, Sean M, Siebert, Reiner, Campo, Elías, Shibata, Tatsuhiro, Pfister, Stefan M, Campbell, Peter J, Stratton, Michael R

All cancers are caused by somatic mutations; however, understanding of the biological processes generating these mutations is limited. The catalogue of somatic mutations from a cancer genome bears the signatures of the mutational processes that have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______109::6e577c103a18e0cba7d99001cfcb581a
https://www.repository.cam.ac.uk/handle/1810/284514

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