Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Ilias Kounatidis"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Invasive fungal diseases have profound effects upon human health and are on increase globally. The World Health Organization (WHO) in 2022 published the fungal priority list calling for improved public health interventions and advance research. Droso
Externí odkaz:
https://doaj.org/article/07450b553f3a4615860a687c6d8e6eb0
Autor:
Luiza Mendonça, Andrew Howe, James B. Gilchrist, Yuewen Sheng, Dapeng Sun, Michael L. Knight, Laura C. Zanetti-Domingues, Benji Bateman, Anna-Sophia Krebs, Long Chen, Julika Radecke, Vivian D. Li, Tao Ni, Ilias Kounatidis, Mohamed A. Koronfel, Marta Szynkiewicz, Maria Harkiolaki, Marisa L. Martin-Fernandez, William James, Peijun Zhang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
In this study, Peijun Zhang and colleagues use cryoFIB/SEM volume imaging and soft x-ray cryo-tomography with cryo-electron tomography (cryoET) of cellular periphery, lamellae, and subtomogram averaging to place critical structural events in the SARS
Externí odkaz:
https://doaj.org/article/b9b8da8ca6324f3b86a304ccbf972dba
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 5 (2022)
Candida infections constitute a blind spot in global public health as very few new anti-fungal drugs are being developed. Genetic surveys of host susceptibilities to such infections using mammalian models have certain disadvantages in that obtaining
Externí odkaz:
https://doaj.org/article/01fc659659754cc6a058e1a36ce55ef6
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 8, Iss 5, Pp 1637-1647 (2018)
Candida glabrata (C. glabrata) forms part of the normal human gut microbiota but can cause life-threatening invasive infections in immune-compromised individuals. C. glabrata displays high resistance to common azole antifungals, which necessitates ne
Externí odkaz:
https://doaj.org/article/6435cfa5680c48698152e76074f571de
Autor:
Patrick Phillips, James M. Parkhurst, Ilias Kounatidis, Chidinma Okolo, Thomas M. Fish, James H. Naismith, Martin A. Walsh, Maria Harkiolaki, Maud Dumoux
Publikováno v:
Life, Vol 11, Iss 8, p 842 (2021)
Chlamydiae are strict intracellular pathogens residing within a specialised membrane-bound compartment called the inclusion. Therefore, each infected cell can, be considered as a single entity where bacteria form a community within the inclusion. It
Externí odkaz:
https://doaj.org/article/64f44ae1b4934a729c27ba86c7e78f61
Autor:
Ilias Kounatidis, Stanislava Chtarbanova, Yang Cao, Margaret Hayne, Dhruv Jayanth, Barry Ganetzky, Petros Ligoxygakis
Publikováno v:
Cell Reports, Vol 19, Iss 4, Pp 836-848 (2017)
During aging, innate immunity progresses to a chronically active state. However, what distinguishes those that “age well” from those developing age-related neurological conditions is unclear. We used Drosophila to explore the cost of immunity in
Externí odkaz:
https://doaj.org/article/b66a2dec93694e12bea5e7953fe613f7
Autor:
Filipa Vaz, Ilias Kounatidis, Gonçalo Covas, Richard M. Parton, Maria Harkiolaki, Ilan Davis, Sergio Raposo Filipe, Petros Ligoxygakis
Publikováno v:
Cell Reports, Vol 27, Iss 8, Pp 2480-2492.e6 (2019)
Summary: In Drosophila, it is thought that peptidoglycan recognition proteins (PGRPs) SA and LC structurally discriminate between bacterial peptidoglycans with lysine (Lys) or diaminopimelic (DAP) acid, respectively, thus inducing differential antimi
Externí odkaz:
https://doaj.org/article/3702d3a2c90b43d59f71ef43962a4719
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Increasing body of evidence indicates that proper glial function plays an important role in neuroprotection and in organismal physiology throughout lifespan. Work done in the model organism Drosophila melanogaster has revealed important aspects of gl
Externí odkaz:
https://doaj.org/article/3a702c45569341fc96c93d495a6d4b78
Autor:
Simon Vann Jones, Ilias Kounatidis
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Alzheimer’s disease (AD) is the most common form of dementia, an eversible, progressive disease that causes problems with memory, thinking, language, planning, and behavior. There are a number of risk factors associated with developing AD but the e
Externí odkaz:
https://doaj.org/article/e50b13cf4736415195c76a2146ee9b72
Autor:
Marcus T. Glittenberg, Ilias Kounatidis, David Christensen, Magali Kostov, Sandra Kimber, Ian Roberts, Petros Ligoxygakis
Publikováno v:
Disease Models & Mechanisms, Vol 4, Iss 4, Pp 515-525 (2011)
SUMMARY Candida albicans systemic dissemination in immunocompromised patients is thought to develop from initial gastrointestinal (GI) colonisation. It is unclear what components of the innate immune system are necessary for preventing C. albicans di
Externí odkaz:
https://doaj.org/article/cf95073bd0874556b6669fd7cc9fb759