Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ilias Dorziotis"'
Autor:
David M. Tschaen, Thoa Hoang, Yoshiaki Kato, Atsushi Akao, Joseph J. Lynch, Audrey Molina, Takayuki Nemoto, Koji Tomimoto, Ralph P. Volante, Toshiaki Mase, Daniel Zewge, Fengrui Lang, Paul J. Reider, Takehiko Iida, Toshihiro Wada, Keisuke Kamei, Shinji Kato, Jaemoon Lee, Takahiro Itoh, Ilias Dorziotis, Peter E. Maligres, Khateeta M. Emerson, Shigemitsu Okada, Masashi Kawasaki, Jake Z. Song, Ioannis N. Houpis, Robert A. Reamer
Publikováno v:
The Journal of Organic Chemistry. 66:6775-6786
An efficient synthesis of a structurally unique, novel M(3) antagonist 1 is described. Compound 1 is conveniently disconnected retrosynthetically at the amide bond to reveal the acid portion 2 and the amine fragment 3. The synthesis of key intermedia
Autor:
Jaemoon Lee, Audrey Molina, Bob Reamer, Ioannis N. Houpis, Paul J. Reider, Ralph P. Volante, Ilias Dorziotis
Publikováno v:
Tetrahedron. 54:1185-1195
Alkyl, aryl, and vinyl Grignard reagents were added to olefin II under Ni(acac) 2 or Cl 2 Ni(PPh 3 ) 2 catalysis to give products with the general formula I in 74–95% yield. Organozincates gave similar results with Ni(acac) 2 as the catalyst.
Autor:
Robert A. Reamer, Ilias Dorziotis, Ralph P. Volante, Paul J. Reider, Ioannis N. Houpis, Audrey Molina
Publikováno v:
Tetrahedron Letters. 38:7131-7134
Ph3ZnMgCl was added to the optically pure sulfoxide 3 in the presence of Ni(acac)2 to give, after desulfurization, the phosphodiesterase IV inhibitor 1 in good yield and 92% enantiomeric excess.
Autor:
Robert A. Reamer, Ioannis N. Houpis, Paul J. Reider, Ralph P. Volante, Audrey Molina, Ilias Dorziotis
Publikováno v:
ChemInform. 29
Ph3ZnMgCl was added to the optically pure sulfoxide 3 in the presence of Ni(acac)2 to give, after desulfurization, the phosphodiesterase IV inhibitor 1 in good yield and 92% enantiomeric excess.
Autor:
Ralph P. Volante, Bob Reamer, Jaemoon Lee, Ioannis N. Houpis, Ilias Dorziotis, Audrey Molina, Paul J. Reider
Publikováno v:
ChemInform. 29
Alkyl, aryl, and vinyl Grignard reagents were added to olefin II under Ni(acac) 2 or Cl 2 Ni(PPh 3 ) 2 catalysis to give products with the general formula I in 74–95% yield. Organozincates gave similar results with Ni(acac) 2 as the catalyst.
Autor:
Toshiaki Mase, Ioannis N. Houpis, Atsushi Akao, Ilias Dorziotis, Khateeta Emerson, Thoa Hoang, Takehiko Iida, Takahiro Itoh, Keisuke Kamei, Shinji Kato, Masashi Kawasaki, Fengrui Lang, Jaemoon Lee, Joseph Lynch, Peter Maligres, Audrey Molina, Takayuki Nemoto, Shigemitsu Okada, Robert Reamer, Zhiguo J. Song, David Tschaen, Toshihiro Wada, David Zewge, R. P. Volante, Paul J. Reider, Koji Tomimoto
Publikováno v:
The Journal of Organic Chemistry. 67:318-318