Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Ilias, Kazanis"'
Autor:
Amber R Philp, Carolina R Reyes, Josselyne Mansilla, Amar Sharma, Chao Zhao, Carlos Valenzuela-Krugmann, Khalil S Rawji, Ginez A Gonzalez Martinez, Penelope Dimas, Bryan Hinrichsen, César Ulloa-Leal, Amie K Waller, Diana M Bessa de Sousa, Maite A Castro, Ludwig Aigner, Pamela Ehrenfeld, Maria Elena Silva, Ilias Kazanis, Cedric Ghevaert, Robin JM Franklin, Francisco J Rivera
Publikováno v:
eLife, Vol 12 (2024)
Revealing unknown cues that regulate oligodendrocyte progenitor cell (OPC) function in remyelination is important to optimise the development of regenerative therapies for multiple sclerosis (MS). Platelets are present in chronic non-remyelinated les
Externí odkaz:
https://doaj.org/article/7461240c98c34149be24d14e2b4bf8cc
Autor:
Theodora Mourtzi, Nasia Antoniou, Christina Dimitriou, Panagiotis Gkaravelas, Georgia Athanasopoulou, Panagiota Nti Kostantzo, Olga Stathi, Efthymia Theodorou, Maria Anesti, Rebecca Matsas, Fevronia Angelatou, Georgia Kouroupi, Ilias Kazanis
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 6, Pp 1318-1324 (2024)
[INLINE:1] We have previously shown the neuroprotective and pro-neurogenic activity of microneurotrophin BNN-20 in the substantia nigra of the “weaver” mouse, a model of progressive nigrostriatal degeneration. Here, we extended our investigation
Externí odkaz:
https://doaj.org/article/aa32d554bcdd43c89dff85501112db93
Reversal of Postnatal Brain Astrocytes and Ependymal Cells towards a Progenitor Phenotype in Culture
Publikováno v:
Cells, Vol 13, Iss 8, p 668 (2024)
Astrocytes and ependymal cells have been reported to be able to switch from a mature cell identity towards that of a neural stem/progenitor cell. Astrocytes are widely scattered in the brain where they exert multiple functions and are routinely targe
Externí odkaz:
https://doaj.org/article/9cb0e3801f33497c898270a2c5727e58
Autor:
Theodora Mourtzi, Ilias Kazanis
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 12, Pp 2637-2642 (2022)
Parkinson’s disease is the second most common neurodegenerative disease and has currently no effective treatment, one that would be able to stop or reverse the loss of dopaminergic neurons in the substantia nigra pars compacta. In addition, Parkins
Externí odkaz:
https://doaj.org/article/9c0dd1b2c1a7426fb39c82861ad2b233
Autor:
Theodora Mourtzi, Dimitrios Dimitrakopoulos, Dimitrios Kakogiannis, Charalampos Salodimitris, Konstantinos Botsakis, Danai Kassandra Meri, Maria Anesti, Aggeliki Dimopoulou, Ioannis Charalampopoulos, Achilleas Gravanis, Nikolaos Matsokis, Fevronia Angelatou, Ilias Kazanis
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-18 (2021)
Abstract Background Loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) underlines much of the pathology of Parkinson’s disease (PD), but the existence of an endogenous neurogenic system that could be targeted as a therapeutic
Externí odkaz:
https://doaj.org/article/f5d062c4b66946bbbffd4ae2e394a452
Publikováno v:
Cells, Vol 11, Iss 11, p 1743 (2022)
Two main stem cell pools exist in the postnatal mammalian brain that, although they share some “stemness” properties, also exhibit significant differences. Multipotent neural stem cells survive within specialized microenvironments, called niches,
Externí odkaz:
https://doaj.org/article/b7360f56d2604b9291d171ace11f3e74
Autor:
Ilias Kazanis, Kimberley A. Evans, Evangelia Andreopoulou, Christina Dimitriou, Christos Koutsakis, Ragnhildur Thora Karadottir, Robin J.M. Franklin
Publikováno v:
Stem Cell Reports, Vol 8, Iss 3, Pp 685-700 (2017)
Two populations of oligodendrogenic progenitors co-exist within the corpus callosum (CC) of the adult mouse. Local, parenchymal oligodendrocyte progenitor cells (pOPCs) and progenitors generated in the subependymal zone (SEZ) cytogenic niche. pOPCs a
Externí odkaz:
https://doaj.org/article/1fdc4f82fb284b55a9bd60e3cb368722
Autor:
Christos Koutsakis, Christina Dimitriou, Paraskevi Kakouri, Asterios Arampatzis, Evangelia Andreopoulou, Sofia Oikonomou, Ilias Kazanis, Melina Patsonis, Michaela Kourla, Dimitrios Dimitrakopoulos, Robin J.M. Franklin, Freyja McClenahan, Rana-Tahir Rasool, Danai-Kassandra Meri
Publikováno v:
Stem Cell Reports
Summary Postnatal brain neural stem and progenitor cells (NSPCs) cluster in anatomically inaccessible stem cell niches, such as the subependymal zone (SEZ). Here, we describe a method for the isolation of NSPCs from live animals, which we term “mil
Autor:
Theodora, Mourtzi, Ilias, Kazanis
Publikováno v:
Neural regeneration research. 17(12)
Parkinson's disease is the second most common neurodegenerative disease and has currently no effective treatment, one that would be able to stop or reverse the loss of dopaminergic neurons in the substantia nigra pars compacta. In addition, Parkinson
Publikováno v:
The International journal of developmental biology. 66(1-2-3)
In the postnatal mammalian brain, neurogenic activity is retained in anatomically restricted areas, driven by pools of Neural Stem Cells (NSCs). These cells and their progeny have been studied intensively as potential targets for regenerative treatme