Applying indirect open-circuit calorimetry to study energy expenditure in gnotobiotic mice harboring different human gut microbial communities

Autor: Ilia G. Halatchev, David O’Donnell, Matthew C. Hibberd, Jeffrey I. Gordon

Publikováno v: Microbiome, Vol 7, Iss 1, Pp 1-8 (2019)

Abstract Given the increasing use of gnotobiotic mouse models for deciphering the effects of human microbial communities on host biology, there is a need to develop new methods for characterizing these animals while maintaining their isolation from e

Externí odkaz: https://doaj.org/article/067bede11b364e598ac65e5f3ee30b47

Inpatient versus outpatient intravenous diuresis for the acute exacerbation of chronic heart failure

Autor: Jay R. McDonald, Kelly B. Ohlms, Wen-Chin Wu, Elma Djukic, Ilia G. Halatchev, Paul A. Heidenreich, Sumitra Balasubramanian

Publikováno v: International Journal of Cardiology. Heart & Vasculature
International Journal of Cardiology: Heart & Vasculature, Vol 36, Iss, Pp 100860-(2021)

Background We established an IV outpatient diuresis (IVOiD) clinic and conducted a quality improvement project to evaluate safety, effectiveness and costs associated with outpatient versus inpatient diuresis for patients presenting with acute decompe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db4955ad937b5441d47554e6f0c8908a
http://europepmc.org/articles/PMC8391052

Wild-type transthyretin cardiac amyloidosis (ATTRwt-CA), previously known as senile cardiac amyloidosis: clinical presentation, diagnosis, management and emerging therapies

Autor: Jingsheng Zheng, Ilia G. Halatchev, Jiafu Ou

Publikováno v: Journal of Thoracic Disease. 10:2034-2045

Cardiac amyloidosis is thought to be a rare group of diseases caused by extracellular deposition of misfolded proteins in the extracellular cardiac matrix resulting in heart failure with preserved ejection fraction (HFpEF). This review focuses on the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e086fcde74160a905cc2bc1e86cd8a7
https://doi.org/10.21037/jtd.2018.03.134

Characterization of leptin-responsive neurons in the caudal brainstem

Autor: Ilia G. Halatchev, Roger D. Cone, Kate L. J. Ellacott

Publikováno v: Endocrinology. 147(7)

The central melanocortin system plays a key role in the regulation of energy homeostasis. Neurons containing the peptide precursor proopiomelanocortin (POMC) are found at two sites in the brain, the arcuate nucleus of the hypothalamus (ARC) and the c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b232540adfc067b540417c465a94e720
https://pubmed.ncbi.nlm.nih.gov/16601142

Peptide YY3-36 inhibits food intake in mice through a melanocortin-4 receptor-independent mechanism

Autor: Roger D. Cone, Ilia G. Halatchev, Kate L. J. Ellacott, Wei Fan

Publikováno v: Endocrinology. 145(6)

Peptide YY(3-36) (PYY(3-36)), a peptide released postprandially by the gut, has been demonstrated to inhibit food intake. Little is known about the mechanism by which PYY(3-36) inhibits food intake, although the peptide has been shown to increase hyp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1a0d373ae269702387b3c7e41814a4b
https://pubmed.ncbi.nlm.nih.gov/15140836