Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ilia A. Toshkov"'
Autor:
Vadim Mett, Oleg V. Kurnasov, Ivan A. Bespalov, Ivan Molodtsov, Craig M. Brackett, Lyudmila G. Burdelya, Andrei A. Purmal, Anatoli S. Gleiberman, Ilia A. Toshkov, Catherine A. Burkhart, Yakov N. Kogan, Ekaterina L. Andrianova, Andrei V. Gudkov, Andrei L. Osterman
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Mett et al. describe development of GP532, a substantially deimmunized derivative of Toll-like receptor 5 (TLR5) agonist entolimod. GP532 has mutations eliminating key B- and T-cell epitopes and an inflammasome-activating domain yet remains a potent
Externí odkaz:
https://doaj.org/article/bcafc6dab7b74c02bc2aec45e9ac993a
Autor:
Vadim I Krivokrysenko, Ilia A Toshkov, Anatoli S Gleiberman, Peter Krasnov, Inna Shyshynova, Ivan Bespalov, Ratan K Maitra, Natalya V Narizhneva, Vijay K Singh, Mark H Whitnall, Andrei A Purmal, Alexander N Shakhov, Andrei V Gudkov, Elena Feinstein
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0135388 (2015)
There are currently no approved medical radiation countermeasures (MRC) to reduce the lethality of high-dose total body ionizing irradiation expected in nuclear emergencies. An ideal MRC would be effective even when administered well after radiation
Externí odkaz:
https://doaj.org/article/6865a28f972e46fe8ca473ec1865cf65
Autor:
Geraldine M. Paszkiewicz, Andrei V. Gudkov, Venkatesh Natarajan, Craig M. Brackett, Gary Haderski, Ilia M. Toshkov, Christopher Johnson, Bojidar M. Kandar, Lyudmila G. Burdelya, Anatoli S. Gleiberman
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0227940 (2020)
PLoS ONE
PLoS ONE
Tumor necrosis factor alpha (TNF) is capable of inducing regression of solid tumors. However, TNF released in response to Toll-like receptor 4 (TLR4) activation by bacterial lipopolysaccharide (LPS) is the key mediator of cytokine storm and septic sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26a390265430f4f724df551b5642f75b
https://doi.org/10.1371/journal.pone.0227940
https://doi.org/10.1371/journal.pone.0227940
Autor:
Ilia A. Toshkov, Satish C. Nair, Diane F. Birt, Ann L. Yaktine, William G. Chaney, Tracy Barnett
Publikováno v:
Molecular Carcinogenesis. 14:10-15
Dietary restriction in experimental animals enhances life span, delays disease, inhibits immunological perturbations, and ameliorates cancer. Protein kinase C (PKC) isozymes mediate signals generated by hormones, growth factors, and neurotransmitters
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a15aebc3a236fe946e14ede1222db2b
https://doi.org/10.1002/mc.2940140104
https://doi.org/10.1002/mc.2940140104
Publikováno v:
International journal of pancreatology : official journal of the International Association of Pancreatology. 15(2)
Coexpression of CA 19-9, DU-PAN-2, and TAG-72 was examined by a multilabeling immunohistochemical procedure in 31 surgically resected human pancreatic carcinomas. CA 19-9 was expressed in 74%, DU-PAN-2 in 84%, and TAG-72 in 65% of the cases. CA 19-9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c10e227781c52ef119f54ef1bcaeccf
https://pubmed.ncbi.nlm.nih.gov/8071575
https://pubmed.ncbi.nlm.nih.gov/8071575
Publikováno v:
International journal of pancreatology : official journal of the International Association of Pancreatology. 10(1)
Pancreatic tumors were induced in guinea fowls inoculated with virus strain Pts-56. Sequential high-resolution light microscopic and ultrastructural studies revealed consecutive occurrence of alterations in the pancreas of the infected birds. From th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9115f1c44afe768f78b9a8dea348ddba
https://pubmed.ncbi.nlm.nih.gov/1661771
https://pubmed.ncbi.nlm.nih.gov/1661771
Publikováno v:
International journal of pancreatology. 5:29-34
Osteopetrosis virus strain MAV-2(0) in guinea fowl pancreas induces early unspecific changes in separate acini and the development of neoplasia among apparently unaffected acinar tissue. The tumors were classified as serous and mucinous adenomas and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0387ad9494d64047c46ed83b0fa0ff13
https://doi.org/10.1007/bf02925695
https://doi.org/10.1007/bf02925695
Publikováno v:
JNCI: Journal of the National Cancer Institute.
Polypous growths of the duodenal mucosa were induced in guinea fowls after iv inoculation o virus strain Pts-56. The growths developed in about 60% of the experimental birds after a latent period of 4-6 months. The chronologic study of the alteration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32b236a4c199ee7b4886443d2674efd5
https://doi.org/10.1093/jnci/79.5.1117
https://doi.org/10.1093/jnci/79.5.1117
Publikováno v:
Journal of the National Cancer Institute. 77(3)
The morphologic lesions in the pancreas of 350 guinea fowls infected with avian osteopetrosis virus strain Pts-56 were studied. Focal unspecific changes in the acinar tissue, including reduction of zymogen content, diminution of cytoplasm, and dilata
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5b1bb6a341259047117f06c1904e679
https://pubmed.ncbi.nlm.nih.gov/3018343
https://pubmed.ncbi.nlm.nih.gov/3018343
Autor:
Gary J Haderski, Bojidar M Kandar, Craig M Brackett, Ilia M Toshkov, Christopher P Johnson, Geraldine M Paszkiewicz, Venkatesh Natarajan, Anatoli S Gleiberman, Andrei V Gudkov, Lyudmila G Burdelya
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0227940 (2020)
Tumor necrosis factor alpha (TNF) is capable of inducing regression of solid tumors. However, TNF released in response to Toll-like receptor 4 (TLR4) activation by bacterial lipopolysaccharide (LPS) is the key mediator of cytokine storm and septic sh
Externí odkaz:
https://doaj.org/article/aff8832bcd384418b01c7670ffe0eb0c