Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Ilhan Tomris"'
Autor:
Ilhan Tomris, Kim M Bouwman, Youri Adolfs, Danny Noack, Roosmarijn van der Woude, Gius Kerster, Sander Herfst, Rogier W Sanders, Marit J van Gils, Geert-Jan Boons, Bart L Haagmans, R Jeroen Pasterkamp, Barry Rockx, Robert P de Vries
Publikováno v:
PLoS Pathogens, Vol 18, Iss 3, p e1010340 (2022)
SARS-CoV-2 attaches to angiotensin-converting enzyme 2 (ACE2) to gain entry into cells after which the spike protein is cleaved by the transmembrane serine protease 2 (TMPRSS2) to facilitate viral-host membrane fusion. ACE2 and TMPRSS2 expression pro
Externí odkaz:
https://doaj.org/article/dcc13b37132847f5b458e98303166130
Autor:
Jelle van Schooten, Marlies M van Haaren, Hui Li, Laura E McCoy, Colin Havenar-Daughton, Christopher A Cottrell, Judith A Burger, Patricia van der Woude, Leanne C Helgers, Ilhan Tomris, Celia C Labranche, David C Montefiori, Andrew B Ward, Dennis R Burton, John P Moore, Rogier W Sanders, Shane Crotty, George M Shaw, Marit J van Gils
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8, p e1009736 (2021)
The development of an effective human immunodeficiency virus (HIV-1) vaccine is a high global health priority. Soluble native-like HIV-1 envelope glycoprotein trimers (Env), including those based on the SOSIP design, have shown promise as vaccine can
Externí odkaz:
https://doaj.org/article/174a04f5de89452fb76d485c54ad2f16
Autor:
Kim M Bouwman, Ilhan Tomris, Hannah L Turner, Roosmarijn van der Woude, Tatiana M Shamorkina, Gerlof P Bosman, Barry Rockx, Sander Herfst, Joost Snijder, Bart L Haagmans, Andrew B Ward, Geert-Jan Boons, Robert P de Vries
Publikováno v:
PLoS Pathogens, Vol 17, Iss 2, p e1009282 (2021)
Receptor binding studies on sarbecoviruses would benefit from an available toolkit of recombinant spike proteins, or domains thereof, that recapitulate receptor binding properties of native viruses. We hypothesized that trimeric Receptor Binding Doma
Externí odkaz:
https://doaj.org/article/0b7db8afaba94b17b22fbc8758f4ac2d
Autor:
Ilhan Tomris, Luca Unione, Linh Nguyen, Pouya Zaree, Kim M. Bouwman, Lin Liu, Zeshi Li, Jelle A. Fok, María Ríos Carrasco, Roosmarijn van der Woude, Anne L. M. Kimpel, Mirte W. Linthorst, Sinan E. Kilavuzoglu, Enrico C. J. M. Verpalen, Tom G. Caniels, Rogier W. Sanders, Balthasar A. Heesters, Roland J. Pieters, Jesús Jiménez-Barbero, John S. Klassen, Geert-Jan Boons, Robert P. de Vries
Publikováno v:
ACS chemical biology. American Chemical Society
SARS-CoV-2 viruses engage ACE2 as a functional receptor with their spike protein. The S1 domain of the spike protein contains a C-terminal receptor binding domain (RBD) and an N-terminal domain (NTD). The NTD of other coronaviruses includes a glycan
Autor:
Shang-Te Danny Hsu, Gour Chand Daskhan, Linh Nguyen, Stephen M. Tompkins, Geert-Jan Boons, Elena N. Kitova, Todd L. Lowary, Tzu-Jing Yang, Ling Han, Kelli A. McCord, Mohamed Elaish, Duong T Bui, Robert P. de Vries, Ilhan Tomris, John S. Klassen, Kim M. Bouwman, Andrew Mason, Pradeep Chopra, Lori J. West, Lara K. Mahal, Steven Willows, Tom C. Hobman, Dhanraj Kumawat, Matthew S. Macauley
Publikováno v:
Nature Chemical Biology, 18(1), 81. Nature Publishing Group
Emerging evidence suggests that host glycans influence severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Here, we reveal that the receptor-binding domain (RBD) of the spike (S) protein on SARS-CoV-2 recognizes oligosaccharides c
Autor:
Barry Rockx, Ilhan Tomris, Robert P. de Vries, Danny Noack, Geert-Jan Boons, Bart L. Haagmans, Kim M. Bouwman, R. Jeroen Pasterkamp, Youri Adolfs, Sander Herfst, Roosmarijn van der Woude
SARS-CoV-2 attaches to angiotensin-converting enzyme 2 (ACE2) to gain entry into cells after which the spike protein is cleaved by the transmembrane serine protease 2 (TMPRRS2) to facilitate viral-host membrane fusion. ACE2 and TMPRRS2 expression pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbe2eefc632bfdef01d8a68669bcdcba
https://doi.org/10.1101/2021.03.24.435771
https://doi.org/10.1101/2021.03.24.435771
Autor:
Gert-Jan Boons, Robert P. de Vries, Pradeep Chopra, Kelli A. McCord, Andrew Mason, John S. Klassen, Steven D Williows, Tzu-Jing Yang, Elena N. Kitova, Kim A Bouwman, Todd L. Lowary, Stephen M. Tompkins, Dhanraj Kumawat, Shang-Te Danny Hsu, Gour C Daskan, Ilhan Tomris, Ling Han, Linh Nguyen, Duong T Bui, Lori J. West, Matthew S. Macauley
Emerging evidence suggests that host glycans influence infection by SARS-CoV-2. Here, we reveal that the receptor-binding domain (RBD) of the spike (S)-protein on SARS-CoV-2 recognizes oligosaccharides containing sialic acid (SA), with preference for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56be4a6393cc2e8e590a11cb16ca24a8
https://doi.org/10.21203/rs.3.rs-318912/v1
https://doi.org/10.21203/rs.3.rs-318912/v1
Autor:
Linh Nguyen, Kelli A. McCord, Duong T. Bui, Kim M. Bouwman, Elena N. Kitova, Dhanraj Kumawat, Gour C. Daskhan, Ilhan Tomris, Ling Han, Pradeep Chopra, Tzu-Jing Yang, Steven D. Willows, Andrew L. Mason, Todd L. Lowary, Lori J. West, Shang-Te Danny Hsu, S. Mark Tompkins, Geert-Jan Boons, Robert P. de Vries, Matthew S. Macauley, John S. Klassen
Emerging evidence suggests that host glycans influence infection by SARS-CoV-2. Here, we reveal that the receptor-binding domain (RBD) of the spike (S)-protein on SARS-CoV-2 recognizes oligosaccharides containing sialic acid (SA), with preference for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94693fd5a0f1e5b8d1a62053ac2da1d8
https://doi.org/10.1101/2021.03.08.434228
https://doi.org/10.1101/2021.03.08.434228
Autor:
Christopher A. Cottrell, Patricia van der Woude, Hui Li, Judith A. Burger, Rogier W. Sanders, Ilhan Tomris, Dennis R. Burton, Leanne C. Helgers, Andrew B. Ward, Laura E. McCoy, Colin Havenar-Daughton, Marlies M. van Haaren, Shane Crotty, Jelle van Schooten, George M. Shaw, John P. Moore, David C. Montefiori, Celia C. LaBranche, Marit J. van Gils
Publikováno v:
PLOS Pathogens
PLoS Pathogens
PLoS pathogens, 17(8):e1009736. Public Library of Science
PLoS Pathogens, Vol 17, Iss 8, p e1009736 (2021)
PLoS Pathogens
PLoS pathogens, 17(8):e1009736. Public Library of Science
PLoS Pathogens, Vol 17, Iss 8, p e1009736 (2021)
The development of an effective human immunodeficiency virus (HIV-1) vaccine is a high global health priority. Soluble native-like HIV-1 envelope glycoprotein trimers (Env), including those based on the SOSIP design, have shown promise as vaccine can
Autor:
Robert P. de Vries, Geert-Jan Boons, Barry Rockx, Ilhan Tomris, Kim M. Bouwman, Sander Herfst, Gerlof P. Bosman, Bart L. Haagmans, Roosmarijn van der Woude, Hannah L. Turner, Andrew B. Ward
Receptor binding studies using recombinant SARS-CoV proteins have been hampered due to challenges in approaches creating spike protein or domains thereof, that recapitulate receptor binding properties of native viruses. We hypothesized that trimeric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b4ab422bd54c61a8fb0f6d8b7e02c4d
https://doi.org/10.1101/2020.09.04.282558
https://doi.org/10.1101/2020.09.04.282558