Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Ilenia Sarnico"'
Autor:
Annamaria Lanzillotta, Giuseppe Pignataro, Caterina Branca, Ornella Cuomo, Ilenia Sarnico, Marina Benarese, Lucio Annunziato, PierFranco Spano, Marina Pizzi
Publikováno v:
Neurobiology of Disease, Vol 49, Iss , Pp 177-189 (2013)
Nuclear factor-kappaB (NF-κB) p50/RelA is a key molecule with a dual effect in the progression of ischemic stroke. In harmful ischemia, but not in preconditioning insult, neurotoxic activation of p50/RelA is characterized by RelA-specific acetylatio
Externí odkaz:
https://doaj.org/article/a51f7c5096a847f2aa7ba4dffb73f3c5
Autor:
Rosaria Ingrassia, Annamaria Lanzillotta, Ilenia Sarnico, Marina Benarese, Francesco Blasi, Laura Borgese, Fabjola Bilo, Laura Depero, Alberto Chiarugi, Pier Franco Spano, Marina Pizzi
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e38019 (2012)
The molecular mechanisms responsible for increasing iron and neurodegeneration in brain ischemia are an interesting area of research which could open new therapeutic approaches. Previous evidence has shown that activation of nuclear factor kappa B (N
Externí odkaz:
https://doaj.org/article/dc47b0461f1c43598fe9856ad3c77386
Autor:
Marina Pizzi, Claudia Balducci, Luciana Giardino, Alessandro Usiello, Arturo R. Viscomi, Gino Villetti, Giuseppe Nisticò, Bruno P. Imbimbo, Annamaria Lanzillotta, Gianluigi Forloni, Luca Lorenzini, Alessandro Giuliani, Ilenia Sarnico, Lydia Mare, Simone Ottonello, Sandra Sivilia, Laura Calzà, Bisan Mehdawy, Robert Nisticò
Publikováno v:
Journal of Alzheimer's Disease. 24:799-816
Abnormal amyloid-β (Aβ) production and deposition is believed to represent one of the main causes of Alzheimer's disease (AD). γ-Secretase is the enzymatic complex responsible for Aβ generation from its precursor protein. Inhibition or modulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c8f1103c9c24466a143010744ae02fb
https://doi.org/10.3233/jad-2011-101839
https://doi.org/10.3233/jad-2011-101839
Autor:
Birgit Hutter-Paier, Cristina Baiguera, Manfred Windisch, Marina Benarese, Marina Pizzi, Bruno P. Imbimbo, PierFranco Spano, Ilenia Sarnico, Annamaria Lanzillotta, Caterina Branca
Publikováno v:
Journal of Molecular Neuroscience. 45:22-31
The relationship between β-amyloid (Aβ) and tau is not fully understood, though it is proposed that in the pathogenesis of Alzheimer's disease (AD) Aβ accumula- tion precedes and promotes tau hyperphosphorylation via activation of glycogen synthas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9687b5d9a6f488714fd92eb0525fc883
https://doi.org/10.1007/s12031-010-9482-2
https://doi.org/10.1007/s12031-010-9482-2
NF-κB p50/RelA and c-Rel-containing dimers: opposite regulators of neuron vulnerability to ischaemia
Autor:
Markus Schwaninger, Manuela Alghisi, Ilenia Sarnico, Marina Pizzi, Ioana Inta, Annamaria Lanzillotta, Marina Benarese, F. Boroni, Leontino Battistin, PierFranco Spano
Publikováno v:
Journal of Neurochemistry. 108:475-485
Diverse nuclear factor-kappaB subunits mediate opposite effects of extracellular signals on neuron survival. While RelA is activated by neurotoxic agents, c-Rel drives neuroprotective effects. In brain ischaemia RelA and p50 factors rapidly activate,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::630e8438b9d76990916d91a93c8a89bd
https://doi.org/10.1111/j.1471-4159.2008.05783.x
https://doi.org/10.1111/j.1471-4159.2008.05783.x
Publikováno v:
FEBS Journal. 276:27-35
Nuclear factor-kappaB (NF-κB) has been proposed to serve a dual function as a regulator of neuron survival in pathological conditions associated with neurodegeneration. NF-κB is a transcription family of factors comprising five different proteins,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c956fc08cacca521dd47b40d438514e
https://doi.org/10.1111/j.1742-4658.2008.06767.x
https://doi.org/10.1111/j.1742-4658.2008.06767.x
Autor:
Marina Benarese, PierFranco Spano, Marina Pizzi, F. Boroni, Alessandra Valerio, Valentina Ghisi, Ilenia Sarnico, Laura Grazia Bresciani, Giuseppe Borsani, Marina Ferrario
Publikováno v:
European Journal of Neuroscience. 23:1711-1720
Beta-amyloid (Abeta) peptides are key proteins in the pathophysiology of Alzheimer's disease (AD). While Abeta42 aggregates very rapidly to form early diffuse plaques, supplemental Abeta40 deposition is required to form mature neuritic plaques. We he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8252f1c1a7ce8ae8a2d2c4f1ec16ce64
https://doi.org/10.1111/j.1460-9568.2006.04722.x
https://doi.org/10.1111/j.1460-9568.2006.04722.x
Autor:
F. Boroni, Francesca Goffi, Andrea Bianchetti, Alessandra Valerio, Marina Pizzi, PierFranco Spano, Costantinos Moraitis, Ilenia Sarnico, Marina Benarese
Publikováno v:
European Journal of Neuroscience. 16:2342-2350
The present study demonstrates that human SK-N-SH neuroblastoma cells, differentiated by retinoic acid (RA), express functional NMDA receptors and become vulnerable to glutamate toxicity. During exposure to RA, SK-N-SH cells switched from non-neurona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2fa069079598074024abc6e7ccc5928
https://doi.org/10.1046/j.1460-9568.2002.02403.x
https://doi.org/10.1046/j.1460-9568.2002.02403.x
Autor:
Annamaria Lanzillotta, Ilenia Sarnico, Simone Ottonello, Bruno P. Imbimbo, Vanessa Porrini, Laura Calzà, Luca Lorenzini, Caterina Branca, Marina Benarese, Arturo Roberto Viscomi, Roberta Ruotolo, Marina Pizzi
Publikováno v:
Scientific Reports
Amyloid precursor protein (APP) intracellular domain (AICD) is a product of APP processing with transcriptional modulation activity, whose overexpression causes various Alzheimer's disease (AD)-related dysfunctions. Here we report that 1-(3′,4′-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db4930d4f2848cfbf78b851e6897124e
https://doi.org/10.1038/srep04618
https://doi.org/10.1038/srep04618
Autor:
Ilenia Sarnico, Giuseppe Pignataro, Marina Benarese, Marina Pizzi, Ornella Cuomo, PierFranco Spano, Caterina Branca, Lucio Annunziato, Annamaria Lanzillotta
Publikováno v:
Neurobiology of Disease, Vol 49, Iss, Pp 177-189 (2013)
Nuclear factor-kappaB (NF-κB) p50/RelA is a key molecule with a dual effect in the progression of ischemic stroke. In harmful ischemia, but not in preconditioning insult, neurotoxic activation of p50/RelA is characterized by RelA-specific acetylatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c70d77b934ef6a2a17deba018c66dc0f
https://pubmed.ncbi.nlm.nih.gov/22971966
https://pubmed.ncbi.nlm.nih.gov/22971966