Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Ilenia Cirilli"'
Autor:
Sinenhlanhla X.H. Mthembu, Sithandiwe E. Mazibuko-Mbeje, Sonia Silvestri, Patrick Orlando, Fabio Marcheggiani, Ilenia Cirilli, Bongani B. Nkambule, Christo J.F. Muller, Luca Tiano, Phiwayinkosi V. Dludla
Publikováno v:
Toxicology Reports, Vol 12, Iss , Pp 234-243 (2024)
Lipid overload or metabolic stress has gained popularity in research that explores pathological mechanisms that may drive enhanced oxidative myocardial damage. Here, H9c2 cardiomyoblasts were exposed to various doses of palmitic acid (0.06 to 1 mM) f
Externí odkaz:
https://doaj.org/article/e77396da464c4fa69f0d42802b1421d5
Autor:
Ilenia Cirilli, Patrick Orlando, Silvana Hrelia, Fabio Marcheggiani, Luca Tiano, Daniela Beghelli, Cristina Angeloni
Publikováno v:
Heliyon, Vol 10, Iss 18, Pp e37854- (2024)
Development and aging significantly impact the cellular levels of Coenzyme Q (CoQ), which is associated with both pathological and physiological conditions. Aim of this study was to describe the CoQ status throughout the lifetime of Drosophila melano
Externí odkaz:
https://doaj.org/article/ef7ab19707ed4dab9a02a9125537ff0e
Publikováno v:
Molecules, Vol 29, Iss 4, p 847 (2024)
Here, we report an adapted protocol using the Promega NAD/NADH-Glo™ Assay kit. The assay normally allows quantification of trace amounts of both oxidized and reduced forms of nicotinamide adenine dinucleotide (NAD) by enzymatic cycling, but we now
Externí odkaz:
https://doaj.org/article/15de90121f724784acf0e38f8755f98a
Autor:
Phiwayinkosi V. Dludla, Ilenia Cirilli, Fabio Marcheggiani, Sonia Silvestri, Patrick Orlando, Ndivhuwo Muvhulawa, Marakiya T. Moetlediwa, Bongani B. Nkambule, Sithandiwe E. Mazibuko-Mbeje, Nokulunga Hlengwa, Sidney Hanser, Duduzile Ndwandwe, Jeanine L. Marnewick, Albertus K. Basson, Luca Tiano
Publikováno v:
Molecules, Vol 28, Iss 18, p 6440 (2023)
Cardiovascular diseases (CVDs) are considered the predominant cause of death globally. An abnormal increase in biomarkers of oxidative stress and inflammation are consistently linked with the development and even progression of metabolic diseases, in
Externí odkaz:
https://doaj.org/article/a37c488530284c8b96d4d8089a502afe
Autor:
Phiwayinkosi V. Dludla, Ilenia Cirilli, Fabio Marcheggiani, Sonia Silvestri, Patrick Orlando, Ndivhuwo Muvhulawa, Marakiya T. Moetlediwa, Bongani B. Nkambule, Sithandiwe E. Mazibuko-Mbeje, Nokulunga Hlengwa, Sidney Hanser, Duduzile Ndwandwe, Jeanine L. Marnewick, Albertus K. Basson, Luca Tiano
Publikováno v:
Molecules, Vol 28, Iss 18, p 6569 (2023)
The consumption of food-derived products, including the regular intake of pepper, is increasingly evaluated for its potential benefits in protecting against diverse metabolic complications. The current study made use of prominent electronic databases
Externí odkaz:
https://doaj.org/article/3397bdda4e9140178eedbba20f81e584
Autor:
Phiwayinkosi V. Dludla, Bongani B. Nkambule, Ilenia Cirilli, Fabio Marcheggiani, Sihle E. Mabhida, Khanyisani Ziqubu, Yonela Ntamo, Babalwa Jack, Tawanda M. Nyambuya, Sidney Hanser, Sithandiwe E. Mazibuko-Mbeje
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 153, Iss , Pp 113439- (2022)
Diabetic neuropathy is a risk factor for developing complications such as autonomic cardiovascular disease, osteoarthropathy, foot ulcers, and infections, which may be the direct cause of death. Even worse, patients plagued by this condition display
Externí odkaz:
https://doaj.org/article/58e75a515e7c401ca6b9fb6675e6faf7
Autor:
Fabio Marcheggiani, Patrick Orlando, Sonia Silvestri, Ilenia Cirilli, Antonella Riva, Giovanna Petrangolini, Francesca Orsini, Luca Tiano
Publikováno v:
Antioxidants, Vol 12, Iss 4, p 964 (2023)
Coenzyme Q10 (CoQ10) bioavailability in vivo is limited due to its lipophilic nature. Moreover, a large body of evidence in the literature shows that muscle CoQ10 uptake is limited. In order to address cell specific differences in CoQ uptake, we comp
Externí odkaz:
https://doaj.org/article/1f1cb2cbcedc4ede8ba167cf48c4c96d
Autor:
Samukelisiwe C. Shabalala, Rabia Johnson, Albertus K. Basson, Khanyisani Ziqubu, Nokulunga Hlengwa, Sinenhlanhla X. H. Mthembu, Sihle E. Mabhida, Sithandiwe E. Mazibuko-Mbeje, Sidney Hanser, Ilenia Cirilli, Luca Tiano, Phiwayinkosi V. Dludla
Publikováno v:
Antioxidants, Vol 11, Iss 10, p 2071 (2022)
Lipid peroxidation, including its prominent byproducts such as malondialdehyde (MDA) and 4-hydroxy-2-nonenal (4-HNE), has long been linked with worsened metabolic health in patients with type 2 diabetes (T2D). In fact, patients with T2D already displ
Externí odkaz:
https://doaj.org/article/2a95b4c21008470bb81af2d226615daf
Autor:
Phiwayinkosi V. Dludla, Patrick Orlando, Sonia Silvestri, Sithandiwe E. Mazibuko-Mbeje, Rabia Johnson, Fabio Marcheggiani, Ilenia Cirilli, Christo J.F. Muller, Johan Louw, Nnini Obonye, Thembeka Nyawo, Bongani B. Nkambule, Luca Tiano
Publikováno v:
Toxicology Reports, Vol 6, Iss , Pp 1240-1245 (2019)
The diabetic heart has been linked with reduced endogenous levels of coenzyme Q9/10 (CoQ), an important antioxidant and component of the electron transport chain. Although CoQ has displayed cardioprotective potential in experimental models of diabete
Externí odkaz:
https://doaj.org/article/4fc12e657c5144fea06dda99f9352cee
Autor:
Patrick Orlando, Ancuta Nartea, Sonia Silvestri, Fabio Marcheggiani, Ilenia Cirilli, Phiwayinkosi V. Dludla, Rosamaria Fiorini, Deborah Pacetti, Monica Rosa Loizzo, Paolo Lucci, Luca Tiano
Publikováno v:
Antioxidants, Vol 11, Iss 2, p 209 (2022)
The levels of bioactive compounds in broccoli and their bioavailability following broccoli intake can be affected by the cooking procedures used for vegetable preparation. In the present pilot study, we compared the human plasma bioavailability of an
Externí odkaz:
https://doaj.org/article/c49e1cc88aa74e72863ced3a48159410