Race/Ethnicity and Protease Inhibitor Use Influence Plasma Tenofovir Exposure in Adults Living with HIV-1 in AIDS Clinical Trials Group Study A5202

Autor: Cindy J. Bednasz, Charles S. Venuto, Qing Ma, Eric S. Daar, Paul E. Sax, Margaret A. Fischl, Ann C. Collier, Kimberly Y. Smith, Camlin Tierney, Edward P. Acosta, Donald E. Mager, Gene D. Morse, Hector H. Bolivar, Sandra Navarro, Susan L. Koletar, Diane Gochnour, Edward Seefried, Julie Hoffman, Judith Feinberg, Michelle Saemann, Kristine Patterson, Donna Pittard, David Currin, Kerry Upton, Michael Saag, Graham Ray, Steven Johnson, Bartolo Santos, Connie A. Funk, Michael Morgan, Brenda Jackson, Pablo Tebas, Aleshia Thomas, Ge-Youl Kim, Michael K. Klebert, Jorge L. Santana, Santiago Marrero, Jane Norris, Sandra Valle, Gary Matthew Cox, Martha Silberman, Sadia Shaik, Ruben Lopez, Margie Vasquez, Demetre Daskalakis, Christina Megill, Todd Stroberg, Jessica Shore, Babafemi Taiwo, Mitchell Goldman, Molly Boston, Jeffrey Lennox, Carlos del Rio, Timothy W. Lane, Kim Epperson, Annie Luetkemeyer, Mary Payne, Barbara Gripshover, Dawn Antosh, Jane Reid, Mary Adams, Sheryl S. Storey, Shelia B. Dunaway, Joel Gallant, Ilene Wiggins, Joan A. Swiatek, Joseph Timpone, Princy Kumar, Ardis Moe, Maria Palmer, Jon Gothing, Joanne Delaney, Kim Whitely, Ann Marie Anderson, Scott M. Hammer, Michael T. Yin, Mamta Jain, Tianna Petersen, Roberto Corales, Christine Hurley, Keith Henry, Bette Bordenave, Amanda Youmans, Mary Albrecht, Richard B. Pollard, Abimbola Olusanya, Paul R. Skolnik, Betsy Adams, Karen T. Tashima, Helen Patterson, Michelle Ukwu, Lauren Rogers, Henry H. Balfour, Kathy A. Fox, Susan Swindells, Frances Van Meter, Gregory Robbins, Nicole Burgett-Yandow, Charles E. Davis, Colleen Boyce, William A. O’Brien, Gerianne Casey, Chiu-Bin Hsaio, Jeffrey L. Meier, Jack T. Stapleton, Donna Mildvan, Manuel Revuelta, Wafaa El Sadr, Avelino Loquere, Nyef El-Daher, Tina Johnson, Robert Gross, Kathyrn Maffei, Valery Hughes, Glenn Sturge, Deborah McMahon, Barbara Rutecki, Michael Wulfsohn, Andrew Cheng, Norbert Bischofberger, Lynn Dix, Qiming Liao

Publikováno v: Antimicrobial Agents and Chemotherapy. 63

AIDS Clinical Trial Group study A5202 (ClinicalTrials.gov identifier {"type":"clinical-trial","attrs":{"text":"NCT00118898","term_id":"NCT00118898"}}NCT00118898) was a phase 3b, randomized, partially blinded equivalence study of open-label atazanavir

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdb699c7a56c4daf00428d4513ced434
https://doi.org/10.1128/aac.01638-18

Safety, Tolerability, and Pharmacokinetic Interactions of the Antituberculous Agent TMC207 (Bedaquiline) With Efavirenz in Healthy Volunteers

Autor: Kelly E, Dooley, Jeong-Gun, Park, Susan, Swindells, Reena, Allen, David W, Haas, Yoninah, Cramer, Francesca, Aweeka, Ilene, Wiggins, Amita, Gupta, Patricia, Lizak, Sonia, Qasba, Rolf, van Heeswijk, Charles, Flexner, Andrea, Weiss

Publikováno v: JAIDS Journal of Acquired Immune Deficiency Syndromes. 59:455-462

BACKGROUND Drug-drug interactions complicate management of coinfection with HIV-1 and Mycobacterium tuberculosis. Bedaquiline (formerly TMC207), an investigational agent for the treatment of tuberculosis, is metabolized by cytochrome P450 (CYP) 3A wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c92952d589c663ea3e5cbbc5061b79ab
https://doi.org/10.1097/qai.0b013e3182410503

Less Bone Loss With Maraviroc- Versus Tenofovir-Containing Antiretroviral Therapy in the AIDS Clinical Trials Group A5303 Study

Autor: Megan Telfer, Joseph Timpone, Tondria Green, Edward P. Acosta, Jay Dwyer, Michael P. DubCrossed Dsign, Ellen S. Chan, Paul E. Sax, David Rusin, Teri Flynn, Raphael J. Landovitz, Todd T. Brown, Carl J. Fichtenbaum, Amy Sbrolla, Jolene Noel-Connor, Cara Wilson, Roula Qaqish, Daniel Reirden, Pamela Poethke, Athe M. N. Tsibris, Olga I. Mendez, Babafemi Taiwo, Jorge Santana, Shelia B. Dunaway, Ge-Youl Kim, Yolanda Smith, Tim Lane, Joseph J. Eron, James F. Rooney, Mark Hite, Vanessa Cajahuaringa, Ilene Wiggins, Cheryl Keenan, Cornelius N Van Dam, Nina Lambert, Beverly E. Sha, Mark Rodrieguez, Orlando Roman, I. Martinez, Miriam Chicurel-Bayard, Cathi Basler, Karen Coleman, Laura A. Napolitano, Robert C. Kalayjian, Bryan Baugh, Fred Nicotera, Baiba Berzins, Roberto C. Arduino, Kathy Melbourne, Tamara James, Mary Adams, Charles Walworth, Kevin Robertson, Alan L. Landay, Princy Kumar, Melody Palmore, Andrea Weiss, Heera R. Jayvant, Christine Griesmer, Igho Ofotokun, Christos J. Petropoulos, Aleshia Thomas, John A. Davis, Pablo Tebas, Amy Gonzales, Patricia Walton, Constance A. Benson, Alex Reinhart, Brenda Jackson, Rose Kim, Bartolo Santos, Ighovwerha Ofotokun, Annie Luetkemeyer, Heather J. Ribaudo, Karin L. Klingman, Jenifer Baer, Amy Dill, Felicia Williams, Michael T. Yin, Christine Hurley, Hector Bolivar, Edward Seefried, Aadia Rana, Sheryl Storey, Margaret A. Fischl, Hannah Bernath, Aristoteles E. Villamil

Publikováno v: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 61(7)

Background. There is a need to prevent or minimize bone loss associated with antiretroviral treatment (ART) initiation. We compared maraviroc (MVC)- to tenofovir disoproxil fumarate (TDF)–containing ART. Methods. This was a double-blind, placebo-co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7ceeb95b46eaab57187a76006535d11
https://pubmed.ncbi.nlm.nih.gov/26060295

Improvement in lipid profiles over 6 years of follow-up in adults with AIDS and immune reconstitution

Autor: Rob Roy MacGregor, David Ragan, Jeff Schouten, Susan Cahill, Ilene Wiggins, Judith Feinberg, Kathryn Maffei, Paige L. Williams, Judith S. Currier, Christine M. Fietzer, Charlene Gaca, Kathy J. Watson, Sandra Valle, Robert A. Salata, Lisa Kessels, James P. Steinberg, Mitchell Goldman, Jody Lawrence, Graham Ray, Tammy O'Hara, Susan L. Koletar, Janet Forcht, Clifford J. Gunthel, Julie Hoffman, William A. O'Brien, J. A. McCutchan, Charles van der Horst, Mark Rodriguez, Charlotte Mills, Charles Gonzales, Robin Worrell-Thorne, Mary M. Payne, Ellen Chusid, Robert L. Murphy, Joan Riddle, Sheryl S Storey, Julia W. Wu, Jane Reid, Beth Zwickl, Jane L. Norris, Gerianne Casey, Rebecca Clark, Henry H. Balfour, Mallory D. Witt, Kathleen Squires, Oluwatoyin Adeyemi, Sadia Shaik, Marshall J. Glesby, Susan E. Cohn, Valery Hughes, Pualette MacDougall, Bev Putnam, Walter Weiss, Harold A. Kessler, Ericka Patrick, Timothy Cooley, Patricia Galloway, Donna Mildvan, Tammy Powell, John McNeil

Objectives The aim of the study was to evaluate long-term changes in lipids and to assess other coronary heart disease (CHD) risk factors in highly experienced AIDS patients with immune reconstitution, and to examine their association with antiretrov

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07ad4de27158fc0e9b0da60fbb4575a1
https://europepmc.org/articles/PMC2778216/