Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Ilene K. Sugino"'
Publikováno v:
Stem Cells Translational Medicine
Retinal cell therapy can have the objectives of rescue (i.e., modulation of metabolic abnormalities primarily for sight preservation) as well as replacement (i.e., replace cells lost due to injury or disease for sight restoration as well as preservat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::424daaf8a175dd348ed49dee573fa0e6
https://doi.org/10.1002/sctm.18-0282
https://doi.org/10.1002/sctm.18-0282
Publikováno v:
Graefe's Archive for Clinical and Experimental Ophthalmology. 251:1515-1528
Retinal pigment epithelium (RPE) cells produce neurotrophic factors that rescue photoreceptors from degeneration. Previously, we showed that conditioned medium (CM) from fetal vs adult RPE cells resulted in significantly better porcine retinal preser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e45909f66fc4e409cb754ab52a3a16e
https://doi.org/10.1007/s00417-013-2326-3
https://doi.org/10.1007/s00417-013-2326-3
Publikováno v:
Experimental Eye Research. 86:189-200
The purpose of this study was to examine the change in integrin expression in adult human retinal pigment epithelium (RPE) after culturing and to characterize the role of integrins in RPE adhesion to aged submacular human Bruch's membrane. Expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2c3a5ddb11a8e22d41558decb00e1e9
https://doi.org/10.1016/j.exer.2007.10.009
https://doi.org/10.1016/j.exer.2007.10.009
Publikováno v:
Experimental Eye Research. 80:235-248
Resurfacing of diseased or iatrogenically damaged Bruch's membrane with healthy retinal pigment epithelium (RPE) has been proposed as adjunctive treatment for age-related macular degeneration (AMD). The purpose of this study was to determine whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72e6a3b85753912579165d20e73842b7
https://doi.org/10.1016/j.exer.2004.09.006
https://doi.org/10.1016/j.exer.2004.09.006
Publikováno v:
Molecular Neurobiology. 28:177-194
Choroidal new vessel (CNV) excision may improve vision in patients with age-related macular degeneration (AMD) by eliminating the source of subretinal bleeding and scarring. Visual recovery after CNV excision is usually poor in AMD patients, probably
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d3226042d2a412c25c2f3159abbb618
https://doi.org/10.1385/mn:28:2:177
https://doi.org/10.1385/mn:28:2:177
Autor:
Marco A. Zarbin, Alessandro A Castellarin, S. Ninomiya, Itsuro Tsukahara, Ilene K. Sugino, Fumihiko Yagi
Publikováno v:
Experimental Eye Research. 74:255-266
Retinal pigment epithelium (RPE) transplantation might replace cells lost as a consequence of choroidal neovascular membrane excision in patients with age-related macular degeneration (AMD). Autologous transplantation of RPE cells harvested from a pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24c9eb6d0b81bd7ee8934e78e50681f5
https://doi.org/10.1006/exer.2001.1123
https://doi.org/10.1006/exer.2001.1123
Publikováno v:
JAMA Ophthalmology. 135:895
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::930d61c672abcdfa61148598a560837a
https://doi.org/10.1001/jamaophthalmol.2017.2276
https://doi.org/10.1001/jamaophthalmol.2017.2276
Autor:
Jianfeng Wang, Ellen Townes-Anderson, Eva Halasz, Ilene K. Sugino, Marco A. Zarbin, Ian P. Whitehead, Amy Pitler
Publikováno v:
Translational Vision Science & Technology
Purpose Retinal detachment disrupts the rod-bipolar synapse in the outer plexiform layer by retraction of rod axons. We showed that breakage is due to RhoA activation whereas inhibition of Rho kinase (ROCK), using Y27632, reduces synaptic damage. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5aed09a820871560052a15dcc83bfed
https://doi.org/10.1167/tvst.6.3.22
https://doi.org/10.1167/tvst.6.3.22
Autor:
Ilene K, Sugino, Qian, Sun, Noounanong, Cheewatrakoolpong, Christopher, Malcuit, Marco A, Zarbin
Publikováno v:
Developments in ophthalmology. 53
Suspensions of human embryonic stem cell-derived retinal pigment epithelium (hES-RPE) and human fetal RPE resurface aged and age-related macular degeneration (AMD) Bruch's membrane to a limited degree at day 21 in organ culture. Survival and differen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::39697c8cfb1d2e1ba89c9060405c2608
https://pubmed.ncbi.nlm.nih.gov/24732767
https://pubmed.ncbi.nlm.nih.gov/24732767
Autor:
Qian Sun, Marco A. Zarbin, Ilene K. Sugino, Noounanong Cheewatrakoolpong, Christopher Malcuit
Publikováno v:
Stem Cell Biology and Regenerative Medicine ISBN: 9781493907861
Suspensions of human embryonic stem cell-derived retinal pigment epithelium (hES-RPE) and human fetal RPE (fRPE) resurface aged and age-related macular degeneration (AMD) Bruch’s membrane (BM) to a limited degree at day 21 in organ culture. The pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8aac57703b951187a9fab171bb0f2e30
https://doi.org/10.1007/978-1-4939-0787-8_14
https://doi.org/10.1007/978-1-4939-0787-8_14
