Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ilena Vincenti"'
Autor:
Nicolas Page, Sylvain Lemeille, Ilena Vincenti, Bogna Klimek, Alexandre Mariotte, Ingrid Wagner, Giovanni Di Liberto, Jonathan Kaye, Doron Merkler
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
The transcriptional adaptation processes of harmful self-reactive CD8+ T cells in the central nervous system are not well understood. Here the authors use a system in which self-reactive and virally generated CD8+ T cells are directly compared in viv
Externí odkaz:
https://doaj.org/article/0a1022f34c2d437e8a387d622d23d03f
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Tissue-resident-memory CD8+ T cells (TRM) have been described as a non-circulating memory T cell subset that persists at sites of previous infection. While TRM in all non-lymphoid organs probably share a core signature differentiation pathway, certai
Externí odkaz:
https://doaj.org/article/13265843334b44bea413280aae9a3863
Autor:
Andreas Agrafiotis, Raphael Dizerens, Ilena Vincenti, Ingrid Wagner, Raphael Kuhn, Danielle Shlesinger, Marcos Manero-Carranza, Tudor-Stefan Cotet, Kai-Lin Hong, Nicolas Page, Nicolas Fonta, Ghazal Shammas, Alexandre Mariotte, Margot Piccinno, Mario Kreutzfeldt, Benedikt Gruntz, Roy Ehling, Alessandro Genovese, Alessandro Pedrioli, Andreas Dounas, Sören Franzenburg, Hayrettin Tumani, Tania Kümpfel, Vladyslav Kavaka, Lisa Ann Gerdes, Klaus Dornmair, Eduardo Beltrán, Annette Oxenius, Sai T. Reddy, Doron Merkler, Alexander Yermanos
Publikováno v:
Acta Neuropathologica. 145:335-355
B cells contribute to the pathogenesis of both cellular- and humoral-mediated central nervous system (CNS) inflammatory diseases through a variety of mechanisms. In such conditions, B cells may enter the CNS parenchyma and contribute to local tissue
Autor:
Danielle Shlesinger, Kai-Lin Hong, Ghazal Shammas, Nicolas Page, Ioana Sandu, Andreas Agrafiotis, Victor Kreiner, Nicolas Fonta, Ilena Vincenti, Ingrid Wagner, Margot Piccinno, Alexandre Mariotte, Bogna Klimek, Raphael Dizerens, Marcos Manero-Carranza, Raphael Kuhn, Roy Ehling, Lester Frei, Keywan Khodaverdi, Camilla Panetti, Nicole Joller, Annette Oxenius, Doron Merkler, Sai T. Reddy, Alexander Yermanos
Publikováno v:
Genes and Immunity, 23
Adaptive immune repertoires are composed by the ensemble of B and T-cell receptors within an individual, reflecting both past and current immune responses. Recent advances in single-cell sequencing enable recovery of the complete adaptive immune rece
Autor:
Andreas Agrafiotis, Raphael Dizerens, Ilena Vincenti, Ingrid Wagner, Raphael Kuhn, Danielle Shlesinger, Marcos Manero-Carranza, Tudor-Stefan Cotet, Kai-Lin Hong, Nicolas Page, Nicolas Fonta, Ghazal Shammas, Alexandre Mariotte, Margot Piccinno, Mario Kreutzfeldt, Benedikt Gruntz, Roy Ehling, Alessandro Genovese, Alessandro Pedrioli, Andreas Dounas, Sören Franzenburg, Vladyslav Kavaka, Lisa Ann Gerdes, Klaus Dornmair, Eduardo Beltrán, Annette Oxenius, Sai T. Reddy, Doron Merkler, Alexander Yermanos
B cells contribute to the pathogenesis of both cellular- and humoral-mediated central nervous system (CNS) inflammatory diseases through a variety of mechanisms. In such conditions, B cells may enter the CNS parenchyma and contribute to local tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4b738ca1916f7c14ffa7b38c87dcd9f
https://doi.org/10.1101/2022.08.29.505678
https://doi.org/10.1101/2022.08.29.505678
Publikováno v:
Current Opinion in Immunology
Current Opinion in Immunology, 2022, 77, pp.102211. ⟨10.1016/j.coi.2022.102211⟩
Current Opinion in Immunology, 2022, 77, pp.102211. ⟨10.1016/j.coi.2022.102211⟩
International audience; Tissue-resident memory T cells (T RM) represent a subset of antigen-experienced T cells that are constantly retained in a given tissue with limited traf cking through the circulation. These cells are characterized by expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8993b4c205a6efe52b4a581ec620f74
https://hal.science/hal-03749081/document
https://hal.science/hal-03749081/document
Autor:
Ingrid Wagner, Giovanni Di Liberto, Doron Merkler, Bogna Klimek, Jonathan Kaye, Nicolas Page, Alexandre Mariotte, Sylvain Lemeille, Ilena Vincenti
Publikováno v:
Nature Communications, Vol. 12, No 1 (2021) P. 1009
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Self-reactive CD8+ T cells are important mediators of progressive tissue damage in autoimmune diseases, but the molecular program underlying these cells’ functional adaptation is unclear. Here we characterize the transcriptional and epigenetic land
Autor:
Mario Kreutzfeldt, Melanie Greter, Doron Merkler, Ingrid Wagner, Noushin Hadadi, Ilena Vincenti, Mary-Aude Rochat, Martina Spiljar, Nicolas Page, Mirko Trajkovski, Ozren Stojanović, Matthias Mack, Bogna Klimek, Dilay Cansever, Claire Chevalier, Nicolas Suárez-Zamorano, Dorothée Rigo, Karin Steinbach
SUMMARYAutoimmunity is energetically costly, but the impact of a metabolically active state on immunity and immune-mediated diseases is unclear. Ly6Chi monocytes are key effectors in CNS autoimmunity with elusive role in priming naïve autoreactive T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d4bc2a547c16771095b00097357fbad
https://doi.org/10.1101/2020.08.28.269563
https://doi.org/10.1101/2020.08.28.269563
Autor:
Nicolas Page, Doron Merkler, Ingrid Wagner, Mario Kreutzfeldt, Mary-Aude Rochat, Claire Chevalier, Dilay Cansever, Olivia Bejuy, Karin Steinbach, Nicolas Suárez-Zamorano, Martina Spiljar, Didier J. Colin, Ilena Vincenti, Ozren Stojanović, Mirko Trajkovski, Matthias Mack, Noushin Hadadi, Bogna Klimek, Dorothée Rigo, Melanie Greter
Publikováno v:
Cell Metabolism
Cell metabolism, Vol. 33, No 11 (2021) pp. 2231-2246.e8
Cell metabolism, Vol. 33, No 11 (2021) pp. 2231-2246.e8
Summary Autoimmunity is energetically costly, but the impact of a metabolically active state on immunity and immune-mediated diseases is unclear. Ly6Chi monocytes are key effectors in CNS autoimmunity with an elusive role in priming naive autoreactiv
Autor:
Ilena Vincenti, Sabine Hoepner, Alfred Zippelius, Ursula Berka, Stephanie Darbre, Magdalena A. Krzyzaniak, Stephan Günther, Nicole Kirchhammer, Carsten Magnus, Romy Kerber, Daniel D. Pinschewer, Weldy V. Bonilla, Josipa Raguz, Sarah Schmidt, Min Lu, Klaus Orlinger, Anna-Friederike Marx, Sandra M. Kallert, Mindaugas Pauzuolis, Doron Merkler
Publikováno v:
Cell Reports Medicine
Cell Reports. Medicine, Vol. 2, No 3 (2021) P. 100209
Cell Reports. Medicine, Vol. 2, No 3 (2021) P. 100209
Summary Therapeutic vaccination regimens inducing clinically effective tumor-specific CD8+ T lymphocyte (CTL) responses are an unmet medical need. We engineer two distantly related arenaviruses, Pichinde virus and lymphocytic choriomeningitis virus,