Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ilektra-Chara Giassa"'
Autor:
Vaclav Hejret, Nandan Mysore Varadarajan, Eva Klimentova, Katarina Gresova, Ilektra-Chara Giassa, Stepanka Vanacova, Panagiotis Alexiou
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Argonaute proteins are instrumental in regulating RNA stability and translation. AGO2, the major mammalian Argonaute protein, is known to primarily associate with microRNAs, a family of small RNA ‘guide’ sequences, and identifies its tar
Externí odkaz:
https://doaj.org/article/f8b38a445ddc4ba58cfc3319cccb785e
Publikováno v:
Biology, Vol 11, Iss 12, p 1798 (2022)
MicroRNAs (miRNAs) are an abundant class of small non-coding RNAs that regulate gene expression at the post-transcriptional level. They are suggested to be involved in most biological processes of the cell primarily by targeting messenger RNAs (mRNAs
Externí odkaz:
https://doaj.org/article/1f1b8d0a850a483abb91a8d8e3382528
Publikováno v:
Biology, Vol 10, Iss 9, p 896 (2021)
Transposable elements (TEs, or mobile genetic elements, MGEs) are ubiquitous genetic elements that make up a substantial proportion of the genome of many species. The recent growing interest in understanding the evolution and function of TEs has reve
Externí odkaz:
https://doaj.org/article/1fbd37edf9814271965f8dc903c5d072
Identifying hit compounds is a principal step in early-stage drug discovery. While many machine learning (ML) approaches have been proposed, in the absence of binding data, molecular docking is the most widely used option to predict binding modes and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f54bcfed956d0dc25fc218a3a205b1f
https://doi.org/10.26434/chemrxiv-2022-68n6h-v2
https://doi.org/10.26434/chemrxiv-2022-68n6h-v2
Autor:
Eva Klimentová, Václav Hejret, Ján Krčmář, Katarína Grešová, Ilektra-Chara Giassa, Panagiotis Alexiou
Publikováno v:
Genes; Volume 13; Issue 12; Pages: 2323
The binding of microRNAs (miRNAs) to their target sites is a complex process, mediated by the Argonaute (Ago) family of proteins. The prediction of miRNA:target site binding is an important first step for any miRNA target prediction algorithm. To dat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::902dcf895dae9065ac9ba06d6c8f91ff
https://pubmed.ncbi.nlm.nih.gov/36553590
https://pubmed.ncbi.nlm.nih.gov/36553590
Publikováno v:
FEBS Letters
Conventional biophysical and chemical biology approaches for delineating relationships between the structure and biological function of nucleic acids (NAs) abstract NAs from their native biological context. However, cumulative experimental observatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::935c840475978ffb8cf922d2a300f581
https://doi.org/10.1002/1873-3468.13054
https://doi.org/10.1002/1873-3468.13054