Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ilektra Kouranti"'
Autor:
Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 5151 (2022)
Cullin 3 (CUL3) is the scaffold of Cullin3 Ring E3-ligases (CRL3s), which use various BTB-adaptor proteins to ubiquitinate numerous substrates targeting their proteasomal degradation. CUL3 mutations, responsible for a severe form of familial hyperkal
Externí odkaz:
https://doaj.org/article/df16924b81fd48c9b4988f7b209e66ad
Autor:
Ilektra Kouranti, Janel R McLean, Anna Feoktistova, Ping Liang, Alyssa E Johnson, Rachel H Roberts-Galbraith, Kathleen L Gould
Publikováno v:
PLoS Biology, Vol 8, Iss 9 (2010)
Ubiquitination and deubiquitination are reciprocal processes that tune protein stability, function, and/or localization. The removal of ubiquitin and remodeling of ubiquitin chains is catalyzed by deubiquitinating enzymes (DUBs), which are cysteine p
Externí odkaz:
https://doaj.org/article/e4e9de052d9f41f7ae960d0eac6142dc
Autor:
Chloé Rafael, Ilektra Kouranti, Irmine Loisel-Ferreira, Xavier Jeunemaitre, Juliette Hadchouel, Waed Abdel Khalek, Eric Clauser
Publikováno v:
Journal of the American Society of Nephrology
Journal of the American Society of Nephrology, American Society of Nephrology, 2019, 30 (5), pp.811-823. ⟨10.1681/ASN.2017121307⟩
J Am Soc Nephrol
Journal of the American Society of Nephrology, American Society of Nephrology, 2019, 30 (5), pp.811-823. ⟨10.1681/ASN.2017121307⟩
J Am Soc Nephrol
Background Mutations in four genes, WNK lysine deficient protein kinase 1 and 4 ( WNK1 and WNK4 ), kelch like family member 3 ( KLHL3 ), or Cullin 3 ( CUL3 ), can result in familial hyperkalemic hypertension (FHHt), a rare Mendelian form of human art
Autor:
Ilektra Kouranti, Rosa Vargas-Poussou, Gerardo Gamba, Marguerite Hureaux, Richard Grimm, Eric Clauser, Robert J. Unwin, Tiffany Migeon, Nirubiah Thurairajasingam, Marcio Do Cruzeiro, Richard A. Coleman, Chloé Rafael, Eduardo R. Argaiz, Xavier Jeunemaitre, Kevin O’Shaugnessy, Stéphanie Baron, Hélène Louis-Dit-Picard, Ivan Tack, Juliette Hadchouel, María Chávez-Canales, Paolo Mulatero, Paul A. Welling, Waed Abdel-Khalek, Xavier Girerd, Stéphane Decramer, Irmine Loisel-Ferreira, Olivier Staub, Sarah Vacle, Gwenaelle Roussey
Publikováno v:
J Clin Invest
Journal of Clinical Investigation
Journal of Clinical Investigation, 2020, 130 (12), pp.6379-6394. ⟨10.1172/JCI94171⟩
Journal of Clinical Investigation
Journal of Clinical Investigation, 2020, 130 (12), pp.6379-6394. ⟨10.1172/JCI94171⟩
International audience; Gain-of-function mutations in with no lysine (K) 1 (WNK1) and WNK4 genes are responsible for familial hyperkalemic hypertension (FHHt), a rare, inherited disorder characterized by arterial hypertension and hyperkalemia with me
Autor:
Ilektra Kouranti, Anne Peyroche
Publikováno v:
Seminars in Cell & Developmental Biology. 23:538-545
DNA damage is a major threat to genome integrity. To reduce its deleterious effects, cells have developed coordinated responses, collectively referred to as the “DNA damage response” pathway (DDR). In multicellular organisms, the DDR pathway has
Autor:
Mickael Machicoane, Arnaud Echard, Laurent Chesneau, Daphné Dambournet, Ilektra Kouranti, Bruno Goud, Mitsunori Fukuda
Publikováno v:
Current Biology. 22(2):147-153
Summary Cytokinesis bridge instability leads to binucleated cells that can promote tumorigenesis in vivo [1]. Membrane trafficking is crucial for animal cell cytokinesis [2–8], and several endocytic pathways regulated by distinct GTPases (Rab11, Ra
Publikováno v:
Journal of Proteome Research
Ubiquitination plays a role in virtually every cellular signaling pathway ranging from cell cycle control to DNA damage response to endocytosis and gene regulation. The bulk of our knowledge of the ubiquitination system is centered on modification of
Autor:
François Payre, Edith Szafer Glusman, Sébastien Carréno, Ilektra Kouranti, Margaret T. Fuller, Arnaud Echard
Publikováno v:
The Journal of Cell Biology
Journal of Cell Biology
Journal of Cell Biology, Rockefeller University Press, 2008, 180 (4), pp.739-746. ⟨10.1083/jcb.200709161⟩
Journal of Cell Biology
Journal of Cell Biology, Rockefeller University Press, 2008, 180 (4), pp.739-746. ⟨10.1083/jcb.200709161⟩
Cell division requires cell shape changes involving the localized reorganization of cortical actin, which must be tightly linked with chromosome segregation operated by the mitotic spindle. How this multistep process is coordinated remains poorly und
Publikováno v:
Current biology : CB. 16(17)
SummaryCytokinesis is the final step of cell division and leads to the physical separation of the daughter cells. After the ingression of a cleavage membrane furrow that pinches the mother cell, future daughter cells spend much of the cytokinesis pha
Autor:
Carmen Garrido, Chris Spahr, Fabrizio Giordanetto, Céline Candé, Jeremy Luban, Guido Kroemer, Eric Daugas, Ilektra Kouranti, Romano T. Kroemer, Nicola Vahsen, Josef M. Penninger, Elise Schmitt
Publikováno v:
Oncogene. 23(8)
Cyclophilin A (CypA) was determined to interact with apoptosis-inducing factor (AIF) by mass spectroscopy, coimmunoprecipitation, pull-down assays, and molecular modeling. During the initial, caspase-independent stage of chromatin condensation that a