Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ileabett M. Echevarria-Vargas"'
Autor:
Patricia Reyes-Uribe, Paul M. Lieberman, Jessie Villanueva, Zhong Deng, Maureen E. Murphy, Ileabett M. Echevarria-Vargas, Jerry W. Shay, Maria Paz Adrianzen-Ruesta, Qin Liu, Ilgen Mender, Dario C. Altieri, Steven Saheb
Publikováno v:
Oncogene
Targeting RAS is one of the greatest challenges in cancer therapy. Oncogenic mutations in NRAS are present in over 25% of melanomas and patients whose tumors harbor NRAS mutations have limited therapeutic options and poor prognosis. Thus far, there a
Autor:
Adriana Roman, Perla M. Báez-Vega, Pablo E. Vivas-Mejia, Josean Flores, Ileabett M. Echevarria Vargas, María J. Marcos-Martínez, Fatma Valiyeva, Joel Encarnacion-Rosado
Publikováno v:
Oncotarget
// Perla M. Baez-Vega 1 , Ileabett M. Echevarria Vargas 1, 2 , Fatma Valiyeva 1 , Joel Encarnacion-Rosado 3 , Adriana Roman 3 , Josean Flores 4 , Maria J. Marcos-Martinez 5, 6 , Pablo E. Vivas-Mejia 1, 2 1 Comprehensive Cancer Center, University of P
Autor:
Yiling Lu, Genevieve M. Boland, Jessie Villanueva, Clemens Krepler, Adam N. Guterres, Rajasekharan Somasundaram, Christin E. Burd, Qin Liu, Dennie T. Frederick, Chaoran Cheng, Andrew V. Kossenkov, Gao Zhang, Ashani T. Weeraratna, Patricia Reyes-Uribe, Gordon B. Mills, Xiaowei Xu, Ravi K. Amaravadi, Ryan J. Sullivan, Andrew E. Aplin, Xiangfan Yin, Keith T. Flaherty, Miao Benchun, Lynn M. Schuchter, Giorgos C. Karakousis, Zhi Wei, Ileabett M. Echevarria-Vargas, Wei Xu, Meenhard Herlyn, Jennifer J.D. Morrissette
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 5, Pp n/a-n/a (2018)
Despite novel therapies for melanoma, drug resistance remains a significant hurdle to achieving optimal responses. NRAS‐mutant melanoma is an archetype of therapeutic challenges in the field, which we used to test drug combinations to avert drug re
Autor:
Cinzia Franchin, Enrico Capobianco, Paolo Sportoletti, Silvia Rocchiccioli, Elena Guzzolino, Nicholas F. Tsinoremas, Monica Evangelista, Laura Poliseno, Alberto Mercatanti, Marianna Vitiello, Giovanni Signore, Giorgio Arrigoni, Simone Lubrano, Andrea Tuccoli, Jessie Villanueva, Ileabett M. Echevarria-Vargas, Laura Comelli, Giorgio Cozza, Letizia Pitto, Zhijie Jiang, Ettore Luzi, Andrea Marranci, Samanta Sarti
Publikováno v:
Molecular Cancer
Molecular Cancer, Vol 16, Iss 1, Pp 1-25 (2017)
Molecular Cancer, Vol 16, Iss 1, Pp 1-25 (2017)
Background The BRAF protein kinase is widely studied as a cancer driver and therapeutic target. However, the regulation of its expression is not completely understood. Results Taking advantage of the RNA-seq data of more than 4800 patients belonging
Autor:
Patricia Reyes-Uribe, Adam N. Guterres, Qin Liu, Xiaowei Xu, Delaine M. Zayas-Bazan Burgos, Ileabett M. Echevarria-Vargas, Amruta Ronghe, Jessie Villanueva, David W. Speicher
Publikováno v:
Cancer Research. 79:3842-3842
Despite novel therapies for melanoma, drug resistance remains a significant hurdle to achieving optimal responses. NRAS mutant melanoma is an archetype of therapeutic challenges in the field, which we used to test drug combinations to avert drug resi
Publikováno v:
Cancer Research. 72:1105-1105
MicroRNAs (miRNAs) are 21-25 nucleotides regulatory involved in silencing mRNAs in a sequence specific manner. Accumulated data has established the central role of various microRNAs in tumor initiation and progression. Furthermore, recent studies rev