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Akademický článek
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Autor:
Scott A. Rivkees, Amanda P. Beck, Michele M. Cox, Christopher C. Wendler, Caroline J. Zeiss, Ildiko Erdelyi
Publikováno v:
OnLine Journal of Biological Sciences. 14:49-56
Diazoxide is an ATP-sensitive potassium channel (KATP) agonist that has been shown to neuroprotective effects. These observations raise the possibility that diazoxide may have potential as a therapeutic agent for other applications. This study invest
Autor:
Ildiko Erdelyi, Martin Lipkin, Elaine Y. Lin, Fred W. Quimby, Natasha Levenkova, Peter R. Holt, John T. Pinto
Publikováno v:
The Journal of Nutrition. 139:2072-2078
A Western-style diet (WD), defined by high-fat, low-calcium, and vitamin D content, is associated with increased risk of human colorectal cancer. Understanding molecular mechanisms altered by the WD is crucial to develop preventive and therapeutic st
Publikováno v:
Histochemistry and Cell Biology. 124:139-149
Versican plays a role in tumor cell proliferation and adhesion and may also regulate cell phenotype. Furthermore, it is one of the pivotal proteoglycans in mesenchymal condensation during prechondrogenesis. We have previously demonstrated accumulatio
Autor:
Rebecca M. Ducore, Amy S. Tidwell, Rajanikarath Maganti, Robert Causey, Betty Wang, Joseph Alroy, John H. Keating, Ildiko Erdelyi, Rolf Pfannl, Philip March, Mark A. Pokras, Bai Jin Zeng, Samuel Eaton, Rita L. Seger, Paola Torres, Nicole T. Waliszewski, Florina S. Tseng, Bain J. Perry, Thomas N. Seyfried, Edwin H. Kolodny, Sureshkumar Muthupalani
Publikováno v:
Molecular genetics and metabolism. 111(4)
G(M1)-gangliosidosis is a rare progressive neurodegenerative disorder due to an autosomal recessively inherited deficiency of lysosomal β-galactosidase. We have identified seven American black bears (Ursus americanus) found in the Northeast United S
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 26(11)
Chemotherapy-induced peripheral neuropathy (CIPN) is a debilitating side effect that occurs in many patients undergoing chemotherapy. It is often irreversible and frequently leads to early termination of treatment. In this study, we have identified t
Publikováno v:
Veterinary parasitology. 101(2)
Four adult dogs that had spent their entire life in Hungary, were found to be infected with filaroid nematodes of the genus Onchocerca . The morphology and location of the parasites as well as pathological lesions were similar to those described earl
Publikováno v:
Veterinary parasitology. 97(3)
An adult male mongrel dog that had spent its entire life in Hungary, was found to have infection with filaroid nematodes of the genus Onchocerca. The gravid male and female parasites were embedded in bean-sized granulomatous masses on the conjunctiva
Autor:
Manjula Santhanakrishnan, Nicholas Theodosakis, Glenn Merlino, David Dankort, Ildiko Erdelyi, David P. Curley, Laura Huang, Goran Micevic, Marcus Bosenberg, Viswanathan Muthusamy, Nabeel Bardeesy, Martin McMahon, William Damsky, Katrina Meeth, Michael A. Davies, M. Raza Zaidi, James T. Platt, Scott Tighe
Publikováno v:
Cancer Cell. (1):41-56
Braf(V600E) induces benign, growth-arrested melanocytic nevus development, but also drives melanoma formation. Cdkn2a loss in Braf(V600E) melanocytes in mice results in rare progression to melanoma, but only after stable growth arrest as nevi. Immedi