Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Ildiko Aradi"'
Autor:
Zsuzsanna Kahan, Daniela Grecea, Martin Smakal, Sergei Tjulandin, Igor Bondarenko, Luca Perjesi, Andras Illes, Karoly Horvat-Karajz, Ildiko Aradi
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background Treatment with recombinant human granulocyte-colony stimulating factor (G-CSF) is accepted standard for prevention of chemotherapy-induced neutropenia. RGB-02 (Gedeon Richter) is a proposed biosimilar to pegylated G-CSF (Neulasta
Externí odkaz:
https://doaj.org/article/b249d2754cfd438da7b013d32c4d7e50
Publikováno v:
Future Oncology. 15:2083-2092
Pegfilgrastim is widely used for the prevention of chemotherapy-induced neutropenia. The development and use of biosimilar agents help to rationalize healthcare expenditure and improve access to modern therapies to all who need them. This review focu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4b5c3249579591dac468860e9414641
https://doi.org/10.2217/fon-2018-0891
https://doi.org/10.2217/fon-2018-0891
Autor:
Igor Bondarenko, Zsuzsanna Kahán, Martin Smakal, Karoly Horvat-Karajz, Andras Illes, Daniela Grecea, Sergei Tjulandin, Luca Perjesi, Ildiko Aradi
Publikováno v:
BMC Cancer
BMC Cancer, Vol 19, Iss 1, Pp 1-10 (2019)
BMC Cancer, Vol 19, Iss 1, Pp 1-10 (2019)
Background Treatment with recombinant human granulocyte-colony stimulating factor (G-CSF) is accepted standard for prevention of chemotherapy-induced neutropenia. RGB-02 (Gedeon Richter) is a proposed biosimilar to pegylated G-CSF (Neulasta®, Amgen)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6078b81798e3bd7c30b1b84933184cc
http://europepmc.org/articles/PMC6364429
http://europepmc.org/articles/PMC6364429
Publikováno v:
Journal of Neurophysiology. 93:437-453
Mossy cell loss and mossy fiber sprouting are two characteristic consequences of repeated seizures and head trauma. However, their precise contributions to the hyperexcitable state are not well understood. Because it is difficult, and frequently impo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebeed0ce7c29aa27faa59e0fca22324d
https://doi.org/10.1152/jn.00777.2004
https://doi.org/10.1152/jn.00777.2004
Publikováno v:
European Journal of Neuroscience. 19:119-130
Computational modelling studies have revealed that heterogeneity in interneuronal networks can powerfully modulate firing rates, responses to excitatory inputs, theta-gamma oscillations and network synchrony. In these previous studies, heterogeneity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27044e8fb2e0788a56e94cc7452db062
https://doi.org/10.1046/j.1460-9568.2003.03096.x
https://doi.org/10.1046/j.1460-9568.2003.03096.x
Publikováno v:
Trends in Pharmacological Sciences. 23:552-557
Hyperpolarization-activated cation channels (h-channels) are key regulators of neuronal excitation and inhibition, and have a rich diversity of subunit composition, distribution, modulation and function. Recent results indicate that the behavior of h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8318d04ba0be27d2fb3694d7dbfb8094
https://doi.org/10.1016/s0165-6147(02)02110-7
https://doi.org/10.1016/s0165-6147(02)02110-7
Publikováno v:
Neuropharmacology. 43:511-522
GABAergic synaptic inputs to principal cells are heterogeneous in terms of their anatomical, molecular and physiological properties. Whether diversity in GABAergic synaptic inputs affects the efficacy of GABAergic inhibition is not understood. Here w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d74d5f028fe8ca3bae6b77843fb0633d
https://doi.org/10.1016/s0028-3908(02)00167-3
https://doi.org/10.1016/s0028-3908(02)00167-3
Publikováno v:
Nature Medicine. 7:331-337
Febrile seizures are the most common type of developmental seizures, affecting up to 5% of children. Experimental complex febrile seizures involving the immature rat hippocampus led to a persistent lowering of seizure threshold despite an upregulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b77d8590d2d8a3f3b45ac4d0d5c42e50
https://doi.org/10.1038/85480
https://doi.org/10.1038/85480
Autor:
P. Benna, Andrew Escayg, Bryan T. MacDonald, G. de Haan, Ildiko Aradi, Miriam H. Meisler, Lori L. Isom, Alan L. Goldin, E. Montalenti, Ivan Soltesz, Jennifer A. Kearney, Dyke P. McEwen, Stephen I. Levin, Jay Spampanato
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 24(44)
A mutation in the sodium channel SCN1A was identified in a small Italian family with dominantly inherited generalized epilepsy with febrile seizures plus (GEFS+). The mutation, D1866Y, alters an evolutionarily conserved aspartate residue in the C-ter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09d67af6018295509addd4d591ccee8b
https://pubmed.ncbi.nlm.nih.gov/15525788
https://pubmed.ncbi.nlm.nih.gov/15525788
Publikováno v:
Journal of neurophysiology. 91(6)
Previous computational modeling studies suggested a set of rules underlying the modulation of principal cell firing rates by heterogeneity in the synaptic parameters (peak amplitude and decay kinetics) of populations of GABAergic inputs. Here we perf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::115d7c495d9a49612adc66c9dc2b4239
https://pubmed.ncbi.nlm.nih.gov/15136604
https://pubmed.ncbi.nlm.nih.gov/15136604