Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ildem Sanli"'
Meg3 Non-coding RNA Expression Controls Imprinting by Preventing Transcriptional Upregulation in cis
Autor:
Ildem Sanli, Sébastien Lalevée, Marco Cammisa, Aurélien Perrin, Florence Rage, David Llères, Andrea Riccio, Edouard Bertrand, Robert Feil
Publikováno v:
Cell Reports, Vol 23, Iss 2, Pp 337-348 (2018)
Summary: Although many long non-coding RNAs (lncRNAs) are imprinted, their roles often remain unknown. The Dlk1-Dio3 domain expresses the lncRNA Meg3 and multiple microRNAs and small nucleolar RNAs (snoRNAs) on the maternal chromosome and constitutes
Externí odkaz:
https://doaj.org/article/a80c873c04964a5684d8a9616f24fed8
Autor:
Eirini M Kallimasioti-Pazi, Keerthi Thelakkad Chathoth, Gillian C Taylor, Alison Meynert, Tracy Ballinger, Martijn J E Kelder, Sébastien Lalevée, Ildem Sanli, Robert Feil, Andrew J Wood
Publikováno v:
PLoS Biology, Vol 16, Iss 12, p e2005595 (2018)
Genome editing occurs in the context of chromatin, which is heterogeneous in structure and function across the genome. Chromatin heterogeneity is thought to affect genome editing efficiency, but this has been challenging to quantify due to the presen
Externí odkaz:
https://doaj.org/article/5d84a8fbada2410c8fe18bed75f1ab24
Autor:
Milica Ng, Ildem Sanli, Adrian Zuercher, Pawel Pelczar, Wy Ching Ng, Fabian Käsermann, Cédric Vonarburg, Alexander Schaub, Charley Mackenzie-Kludas, Ian K. Campbell, Lorena E. Brown, Monther Alhamdoosh, Sandra Koernig, Roland Zehnder, Marius Loetscher
Publikováno v:
Mucosal Immunology
Recurrent and persistent airway infections remain prevalent in patients with primary immunodeficiency (PID), despite restoration of serum immunoglobulin levels by intravenous or subcutaneous plasma-derived IgG. We investigated the effectiveness of di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6b4716cf962d707803fc16b343723dd
https://doi.org/10.1038/s41385-019-0167-z
https://doi.org/10.1038/s41385-019-0167-z
Autor:
Alison M. Meynert, Andrew J. Wood, Martijn J. E. Kelder, Robert Feil, Tracy Ballinger, Keerthi T. Chathoth, Ildem Sanli, Eirini M. Kallimasioti-Pazi, Sébastien Lalevée, Gillian C.A. Taylor
CRISPR-Cas9 genome editing occurs in the context of chromatin, which is heterogeneous in structure and function across the genome. Chromatin heterogeneity is thought to affect genome editing efficiency, but this has been challenging to quantify due t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0ca727ec93106708b2122e5b68936ca
Autor:
Ildem Sanli, Robert Feil
Publikováno v:
Epigenomics
Epigenomics, Future Medicine, 2016, 8 (6), pp.733--5. ⟨10.2217/epi-2016-0029⟩
Epigenomics, Future Medicine, 2016, 8 (6), pp.733--5. ⟨10.2217/epi-2016-0029⟩
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::612e2da3d1b320a2d68b5c8b6fc81779
https://pubmed.ncbi.nlm.nih.gov/27286274
https://pubmed.ncbi.nlm.nih.gov/27286274
Autor:
Ildem, Sanli, Robert, Feil
Publikováno v:
The international journal of biochemistrycell biology. 67
Hundreds of protein-coding genes and regulatory non-coding RNAs (ncRNAs) are subject to genomic imprinting. The mono-allelic DNA methylation marks that control imprinted gene expression are somatically maintained throughout development, and this proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::39fd32bfb3dc2571c35ee3466591c480
https://pubmed.ncbi.nlm.nih.gov/25908531
https://pubmed.ncbi.nlm.nih.gov/25908531
Autor:
Satya K. Kota, Ildem Sanli, Christina Begon-Pescia, Tristan Bouschet, Philippe Arnaud, David Llères, Laurent Journot, Michael Girardot, Robert Feil, Alice Marchand, Ryutaro Hirasawa
Publikováno v:
Developmental Cell
Developmental Cell, Elsevier, 2014, 31 (1), pp.19-33. ⟨10.1016/j.devcel.2014.08.009⟩
Developmental Cell, Elsevier, 2014, 31 (1), pp.19-33. 〈10.1016/j.devcel.2014.08.009〉
Developmental Cell, Elsevier, 2014, 31 (1), pp.19-33. ⟨10.1016/j.devcel.2014.08.009⟩
Developmental Cell, Elsevier, 2014, 31 (1), pp.19-33. 〈10.1016/j.devcel.2014.08.009〉
SummaryImprinted genes play essential roles in development, and their allelic expression is mediated by imprinting control regions (ICRs). The Dlk1-Dio3 locus is among the few imprinted domains controlled by a paternally methylated ICR. The unmethyla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4d137b299e0c4a699e6056944934859
https://hal.archives-ouvertes.fr/hal-01934520
https://hal.archives-ouvertes.fr/hal-01934520