Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Ildar R. Alembekov"'
Autor:
Nickolai A. Tchurikov, Amalia A. Vartanian, Elena S. Klushevskaya, Ildar R. Alembekov, Antonina N. Kretova, Viktoriya N. Lukicheva, Vladimir R. Chechetkin, Galina I. Kravatskaya, Vyacheslav S. Kosorukov, Yuri V. Kravatsky
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9291 (2024)
Gene expression patterns are very sensitive to external influences and are reflected in phenotypic changes. It was previously described that transferring melanoma cells from a plastic surface to Matrigel led to formation of de novo vascular networks
Externí odkaz:
https://doaj.org/article/68f34685a452430094da0995e9bbeba3
Autor:
Nickolai A. Tchurikov, Ildar R. Alembekov, Elena S. Klushevskaya, Antonina N. Kretova, Viktoriya N. Lukicheva, Vladimir R. Chechetkin, Galina I. Kravatskaya, Yuri V. Kravatsky
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6333 (2024)
Different developmental genes shape frequent dynamic inter-chromosomal contacts with rDNA units in human and Drosophila cells. In the course of differentiation, changes in these contacts occur, coupled with changes in the expression of hundreds of rD
Externí odkaz:
https://doaj.org/article/02c0ecb04ca04c69bc2f9946e954296b
Autor:
Nickolai A. Tchurikov, Elena S. Klushevskaya, Ildar R. Alembekov, Antonina N. Kretova, Vladimir R. Chechetkin, Galina I. Kravatskaya, Yuri V. Kravatsky
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 9842 (2023)
The expression of clusters of rDNA genes influences pluripotency; however, the underlying mechanisms are not yet known. These clusters shape inter-chromosomal contacts with numerous genes controlling differentiation in human and Drosophila cells. Thi
Externí odkaz:
https://doaj.org/article/78e98e672ab441b3a6b200a67c62caeb
Autor:
Nickolai A. Tchurikov, Ildar R. Alembekov, Elena S. Klushevskaya, Antonina N. Kretova, Ann M. Keremet, Anastasia E. Sidorova, Polina B. Meilakh, Vladimir R. Chechetkin, Galina I. Kravatskaya, Yuri V. Kravatsky
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7201 (2022)
Double-strand DNA breakes (DSBs) are the most deleterious and widespread examples of DNA damage. They inevitably originate from endogenous mechanisms in the course of transcription, replication, and recombination, as well as from different exogenous
Externí odkaz:
https://doaj.org/article/e8cd02e1070e4e259385588d3a98c954
Autor:
Nickolai A. Tchurikov, Elena S. Klushevskaya, Ildar R. Alembekov, Anastasiia S. Bukreeva, Antonina N. Kretova, Vladimir R. Chechetkin, Galina I. Kravatskaya, Yuri V. Kravatsky
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 6, p 3014 (2022)
Small noncoding RNAs of different origins and classes play several roles in the regulation of gene expression. Here, we show that diverged and rearranged fragments of rDNA units are scattered throughout the human genome and that endogenous small nonc
Externí odkaz:
https://doaj.org/article/92946db2facd4fda99d180b95d64cc75
Autor:
Nickolai A. Tchurikov, Elena S. Klushevskaya, Daria M. Fedoseeva, Ildar R. Alembekov, Galina I. Kravatskaya, Vladimir R. Chechetkin, Yuri V. Kravatsky, Olga V. Kretova
Publikováno v:
Cells, Vol 9, Iss 12, p 2587 (2020)
Chromosomes are organized into 3D structures that are important for the regulation of gene expression and differentiation. Important role in formation of inter-chromosome contacts play rDNA clusters that make up nucleoli. In the course of differentia
Externí odkaz:
https://doaj.org/article/4bb5ee7e87724caf8bc55aab7bfddccf
Publikováno v:
BioTechniques, Vol 52, Iss 5, Pp 1-3 (2012)
RNAi has potential as an antiviral gene therapy strategy. Cassette constructs simultaneously expressing several siRNAs could prove to be the most efficient technique in developing gene therapy approaches for highly mutable viruses such as HIV-1. Here
Externí odkaz:
https://doaj.org/article/c54df1cca79042579aca9594dfcefd69
Autor:
Kravatsky, Nickolai A. Tchurikov, Elena S. Klushevskaya, Ildar R. Alembekov, Antonina N. Kretova, Vladimir R. Chechetkin, Galina I. Kravatskaya, Yuri V.
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 12; Pages: 9842
The expression of clusters of rDNA genes influences pluripotency; however, the underlying mechanisms are not yet known. These clusters shape inter-chromosomal contacts with numerous genes controlling differentiation in human and Drosophila cells. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::e9da3e2597ab2a3d9f87b7e1d276ac82
Autor:
Ildar R. Alembekov, Olga V. Kretova, Nickolai A. Tchurikov, Y. V. Kravatsky, I Y Slovohotov, D. M. Fedoseeva, E. S. Klushevskaya
Publikováno v:
Молекулярная биология. 54:262-266
rDNA genes play an important role in epigenetic regulation and in differentiation of eukaryotic cells. Using the 4C (circular chromosome conformation capture) approach and model HEK293T cells, we analyzed the rDNA-contacting gene FANK1, using anchor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64abe74cbbf84778531eb6a243d08249
https://doi.org/10.31857/s002689842002007x
https://doi.org/10.31857/s002689842002007x
Autor:
G.I. Kravatskaya, E. S. Klushevskaya, Maria A. Lagarkova, Vsevolod Yu. Makeev, L. A. Uroshlev, Yuri V. Kravatsky, Ildar R. Alembekov, Nickolai A. Tchurikov
Publikováno v:
Cancers
Cancers, Vol 13, Iss 3889, p 3889 (2021)
Volume 13
Issue 15
Cancers, Vol 13, Iss 3889, p 3889 (2021)
Volume 13
Issue 15
Simple Summary There are nine DSB hot spots located in the non-transcribed spacer of human rDNA units. Circular chromosome conformation capture data indicate that the rDNA clusters often shape contact with a specific set of chromosomal regions contai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b465aef4150832e2e8d5f2cde2edf999
http://europepmc.org/articles/PMC8345467
http://europepmc.org/articles/PMC8345467