Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Ilaria Secco"'
Autor:
Sara G. Romeo, Ilaria Secco, Edoardo Schneider, Christina M. Reumiller, Celio X. C. Santos, Anna Zoccarato, Vishal Musale, Aman Pooni, Xiaoke Yin, Konstantinos Theofilatos, Silvia Cellone Trevelin, Lingfang Zeng, Giovanni E. Mann, Varun Pathak, Kevin Harkin, Alan W. Stitt, Reinhold J. Medina, Andriana Margariti, Manuel Mayr, Ajay M. Shah, Mauro Giacca, Anna Zampetaki
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract The microvasculature plays a key role in tissue perfusion and exchange of gases and metabolites. In this study we use human blood vessel organoids (BVOs) as a model of the microvasculature. BVOs fully recapitulate key features of the human m
Externí odkaz:
https://doaj.org/article/353954422197417aa51e7b271e88c1e2
Autor:
Ambra Cappelletto, Harriet E. Allan, Marilena Crescente, Edoardo Schneider, Rossana Bussani, Hashim Ali, Ilaria Secco, Simone Vodret, Roberto Simeone, Luca Mascaretti, Serena Zacchigna, Timothy D. Warner, Mauro Giacca
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2023)
Thrombosis of the lung microvasculature is a characteristic of COVID-19 disease, which is observed in large excess compared to other forms of acute respiratory distress syndrome and thus suggests a trigger for thrombosis that is endogenous to the lun
Externí odkaz:
https://doaj.org/article/4d9c6b235b4c46048734a1b26cae79e3
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Drug repositioning continues to be the most effective, practicable possibility to treat COVID-19 patients. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus enters target cells by binding to the ACE2 receptor via its spike (S) gl
Externí odkaz:
https://doaj.org/article/ac7b55d75688428b8e50b5e397480baa
Autor:
Ilaria Secco, Ana Backovic, Simone Vodret, Matteo Dal Ferro, Mateusz Tomczyk, Khatia Gabisonia, Lucia Carlucci, Lorena Zentilin, Serena Zacchigna, Fabio A Recchia, Mauro Giacca
Publikováno v:
Circulation Research. 131
To what extent cardiac renewal occurs in adulthood and can be stimulated by therapeutic interventions is still a matter of investigation. In particular, over the last few years, significant effort has been made into awakening the endogenous regenerat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d3b16043c27aa637d03fad2d223b04b
https://doi.org/10.1161/res.131.suppl_1.p1019
https://doi.org/10.1161/res.131.suppl_1.p1019
Autor:
Ambra Cappelletto, Harriet E. Allan, Marilena Crescente, Edoardo Schneider, Rossana Bussani, Hashim Ali, Ilaria Secco, Simone Vodret, Roberto Simeone, Luca Mascaretti, Serena Zacchigna, Timothy D. Warner, Mauro Giacca
Publikováno v:
Cappelletto, A, Allan, H E, Crescente, M, Schneider, E, Bussani, R, Ali, H, Secco, I, Vodret, S, Mascaretti, L, Zacchigna, S, Warner, T D, Giacca, M & Simeone, R 2022, ' SARS-CoV-2 Spike protein activates TMEM16F-mediated platelet pro-coagulant activity ', Frontiers in Cardiovascular Medicine .
BackgroundThrombosis of the lung micro-vasculature is a characteristic of COVID-19 disease, which is observed in large excess compared to other forms of acute respiratory distress syndrome and thus suggests a trigger for thrombosis endogenous to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43a930feb76bb8ef34f8ab108782cddb
https://doi.org/10.1101/2021.12.14.472668
https://doi.org/10.1101/2021.12.14.472668
Autor:
Ilaria Secco, Ana Backovic, Simone Vodret, Matteo Dal Ferro, Mateusz Tomczyk, Khatia Gabisonia, Lucia Carlucci, Lorena Zentilin, Serena Zacchigna, Fabio A. Recchia, Mauro Giacca
Publikováno v:
Journal of Molecular and Cellular Cardiology. 173:109
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2bd9a1cfc18957d4696d11ef1d0bf65
https://doi.org/10.1016/j.yjmcc.2022.08.217
https://doi.org/10.1016/j.yjmcc.2022.08.217
Autor:
Hashim Ali, Ilaria Secco, Daniel H. Goldhill, Jose M. Jimenez-Guardeño, Luca Braga, Juan Burrone, Giorgia Rizzari, Guilherme Neves, Antonio Cannatà, Edoardo Schneider, Chiara Collesi, Mauro Giacca, Ajay M. Shah, Michael H. Malim, Rebecca Penn, Wendy S. Barclay, Elena Chiavacci, Daniele Arosio, Rossana Bussani, Ana Maria Ortega-Prieto
Publikováno v:
Nature
Nature (Lond.) 594 (2021): 88–93. doi:10.1038/s41586-021-03491-6
info:cnr-pdr/source/autori:Braga L.; Ali H.; Secco I.; Chiavacci E.; Neves G.; Goldhill D.; Penn R.; Jimenez-Guardeno J.M.; Ortega-Prieto A.M.; Bussani R.; Cannata A.; Rizzari G.; Collesi C.; Schneider E.; Arosio D.; Shah A.M.; Barclay W.S.; Malim M.H.; Burrone J.; Giacca M./titolo:Drugs that inhibit TMEM16 proteins block SARS-CoV-2 spike-induced syncytia/doi:10.1038%2Fs41586-021-03491-6/rivista:Nature (Lond.)/anno:2021/pagina_da:88/pagina_a:93/intervallo_pagine:88–93/volume:594
Nature (Lond.) 594 (2021): 88–93. doi:10.1038/s41586-021-03491-6
info:cnr-pdr/source/autori:Braga L.; Ali H.; Secco I.; Chiavacci E.; Neves G.; Goldhill D.; Penn R.; Jimenez-Guardeno J.M.; Ortega-Prieto A.M.; Bussani R.; Cannata A.; Rizzari G.; Collesi C.; Schneider E.; Arosio D.; Shah A.M.; Barclay W.S.; Malim M.H.; Burrone J.; Giacca M./titolo:Drugs that inhibit TMEM16 proteins block SARS-CoV-2 spike-induced syncytia/doi:10.1038%2Fs41586-021-03491-6/rivista:Nature (Lond.)/anno:2021/pagina_da:88/pagina_a:93/intervallo_pagine:88–93/volume:594
COVID-19 is a disease with unique characteristics that include lung thrombosis1, frequent diarrhoea2, abnormal activation of the inflammatory response3 and rapid deterioration of lung function consistent with alveolar oedema4. The pathological substr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ee8ef2a9edf1c3b1df8e8a7186d90cf
http://hdl.handle.net/11368/2993737
http://hdl.handle.net/11368/2993737
Autor:
Hashim Ali, Ilaria Secco, Luca Braga, Maria Concetta Volpe, Chiara Collesi, Serena Zacchigna, Giorgio Berlot, Fabrizio Zanconati, Andrea Colliva, Lorena Zentilin, Mauro Giacca, Rossana Bussani, Furio Silvestri, Edoardo Schneider
COVID-19 is a deadly pulmonary disease with unique clinical features. A thorough understanding of the molecular and histological correlates of the disease is still missing, especially because post-mortem analysis of COVID-19-affected organs has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29b7930bbce31b00980fe2a68f6816d5
Publikováno v:
Cardiovascular Research
Cardiovasc Res
Cardiovasc Res
A growing body of evidence indicates that cardiac regeneration after myocardial infarction can be achieved by stimulating the endogenous capacity of cardiomyocytes to replicate. This process is controlled, both positively and negatively, by a large s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::943755ba51ee76e7cdafa7def3ef3e35
Autor:
Mauro Giacca, Serena Zacchigna, Rossana Bussani, Lorena Zentilin, Gianfranco Sinagra, Lucia Carlucci, Hashim Ali, Ilaria Secco, Giulia Prosdocimo, Lorenzo Zandonà, Nikoloz Gorgodze, Chiara Collesi, Khatia Gabisonia, Marcello Piacenti, Fabio A. Recchia, Fabio Bernini, Silvia Burchielli, Luca Braga, Giovanni Donato Aquaro
Publikováno v:
Nature
Gabisonia, K, Prosdocimo, G, Aquaro, G D, Carlucci, L, Zentilin, L, Secco, I, Ali, H, Braga, L, Gorgodze, N, Bernini, F, Burchielli, S, Collesi, C, Zandonà, L, Sinagra, G, Piacenti, M, Zacchigna, S, Bussani, R, Recchia, F A & Giacca, M 2019, ' MicroRNA therapy stimulates uncontrolled cardiac repair after myocardial infarction in pigs ', Nature, vol. 569, no. 7756, pp. 418-422 . https://doi.org/10.1038/s41586-019-1191-6
Gabisonia, K, Prosdocimo, G, Aquaro, G D, Carlucci, L, Zentilin, L, Secco, I, Ali, H, Braga, L, Gorgodze, N, Bernini, F, Burchielli, S, Collesi, C, Zandonà, L, Sinagra, G, Piacenti, M, Zacchigna, S, Bussani, R, Recchia, F A & Giacca, M 2019, ' MicroRNA therapy stimulates uncontrolled cardiac repair after myocardial infarction in pigs ', Nature, vol. 569, no. 7756, pp. 418-422 . https://doi.org/10.1038/s41586-019-1191-6
Prompt coronary catheterization and revascularization have dramatically improved the outcome of myocardial infarction, but also have resulted in a growing number of survived patients with permanent structural damage of the heart, which frequently lea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed62c49c6f3d9049dcc3442df0e0334b
http://hdl.handle.net/11368/2944010
http://hdl.handle.net/11368/2944010