Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ilaria Sartori"'
Autor:
Tony Y. Wang, Chiara Piubelli, Lee T. Schaller, Pierette Banker, Stefano Tacconi, Paula Selley, Todd W. Shearer, Robert A. Reid, Federico Faggioni, Daniel J. Price, Richard F. Cox, Shawn P. Williams, David H. Drewry, Michela Tessari, Richard G. Buckholz, Patrick R. Maloney, Paul R. Reid, Brian D. Thompson, Xi Liang, Jeffery L. Smith, Octerloney B. McDonald, Ilaria Sartori
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 28:1958-1963
Hypothalamic CAMKK2 represents a potential mechanism for chemically affecting satiety and promoting weight loss in clinically obese patients. Single-digit nanomolar inhibitors of CAMKK2 were identified in three related ATP-competitive series. Limited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77ef3d3a14b6690b03d61d51517e7124
https://doi.org/10.1016/j.bmcl.2018.03.034
https://doi.org/10.1016/j.bmcl.2018.03.034
Publikováno v:
Ocular Fluid Dynamics ISBN: 9783030258856
Statistical models provide a variety of powerful methods for data analysis in medicine. In this chapter, we aim at illustrating the insights that statistical models can provide regarding the study of disease progression. In particular, we analyze a u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0ea713f2758ac6672ba5cf765ea82ca
http://hdl.handle.net/11311/1126799
http://hdl.handle.net/11311/1126799
Autor:
Ilaria Sartori, Laura Zonzini, Laurie J. Gordon, Angela Worby, Stefano Fontana, Manuela Borriello, Silvia Bison, Jeannette M. Watson, Steven Mark Bromidge, Giovanna Dal Forno, Colin Philip Leslie, Alessandra Pasquarello, Anna Sava, Luca G. Moccia, Barbara Bertani, Roberto Arban, Daniele Donati, Enrica Granci, Valeria Zucchelli, Paolo Cavanni, Massimo Gianotti, Romano Di-Fabio
Publikováno v:
Journal of Medicinal Chemistry. 53:5827-5843
Bioisoteric replacement of the metabolically labile N-methyl amide group of a series of benzoxazinones with small heterocyclic rings has led to novel series of fused tricyclic benzoxazines which are potent 5-HT1A/B/D receptor antagonists with and wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2fb74da943dfb46e7a247dd0b3079e2
https://doi.org/10.1021/jm100482n
https://doi.org/10.1021/jm100482n
Autor:
Adam J. Lucas, Filippo Andreetta, Kevin D. Read, Declan N.C. Jones, Charles H. Large, Andrea M. Bradford, Simon T. Bate, Ilaria Sartori, Silvia Bison, Nigel E. Austin, Giuseppe Alvaro, Nicoletta Garbati, Mikhail Kalinichev
Publikováno v:
Epilepsia. 51:1543-1551
Summary Purpose: Many patients with epilepsy are refractory to anticonvulsant drugs or do not tolerate side effects associated with the high doses required to fully prevent seizures. Antagonists of neurokinin-1 (NK1) receptors have the potential to r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcf8375253ccd4cd42fb824b898d1fac
https://doi.org/10.1111/j.1528-1167.2009.02482.x
https://doi.org/10.1111/j.1528-1167.2009.02482.x
Autor:
Andrea M. Bradford, Adam J. Lucas, Alberto Ruffo, Kevin D. Read, Nigel E. Austin, Giuseppe Alvaro, Mikhail Kalinichev, Corrado Carignani, Charles H. Large, Declan N.C. Jones, Ilaria Sartori, Nicoletta Garbati
Publikováno v:
Epilepsy Research. 85:96-106
The development of novel anticonvulsant drugs with improved efficacy for the treatment of epilepsy is hindered by a lack of information regarding the quantitative relationship between target mechanism and in vivo efficacy. In the present study we hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5da82e2b0be24a1ca5e28704e1466ef
https://doi.org/10.1016/j.eplepsyres.2009.02.018
https://doi.org/10.1016/j.eplepsyres.2009.02.018
Autor:
Ilaria Sartori
Publikováno v:
Annales d'Ethiopie. 23:135-151
Musical traditions are among the most significant expressions of Harar's intangible cultural heritage. Gey fäqär, the sung poetry of Harar, is usually played in a voice-percussion configuration and combines the expression of a shared literary and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9089c1c8f352db36dbb3b6a558c44455
https://doi.org/10.3406/ethio.2007.1502
https://doi.org/10.3406/ethio.2007.1502
Autor:
Marinella Antolini, Silvia Bison, Kevin D. Read, Alessandro Gozzi, Ilaria Sartori, Martin J. Gunthorpe, Giuseppe Alvaro, Charles H. Large, Catherine H. Gill, Jo C. Neill, Emma C. Hollands, Nagi F. Idris, Davide Quarta
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 338(1)
Sodium channel inhibition is a well precedented mechanism used to treat epilepsy and other hyperexcitability disorders. The established sodium channel blocker and broad-spectrum anticonvulsant lamotrigine is also effective in the treatment of bipolar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f7698852dd5c1ff1dc40365e4d24927
https://pubmed.ncbi.nlm.nih.gov/21487071
https://pubmed.ncbi.nlm.nih.gov/21487071
Autor:
Steven M, Bromidge, Roberto, Arban, Barbara, Bertani, Silvia, Bison, Manuela, Borriello, Paolo, Cavanni, Giovanna, Dal Forno, Romano, Di-Fabio, Daniele, Donati, Stefano, Fontana, Massimo, Gianotti, Laurie J, Gordon, Enrica, Granci, Colin P, Leslie, Luca, Moccia, Alessandra, Pasquarello, Ilaria, Sartori, Anna, Sava, Jeannette M, Watson, Angela, Worby, Laura, Zonzini, Valeria, Zucchelli
Publikováno v:
Journal of medicinal chemistry. 53(15)
Bioisoteric replacement of the metabolically labile N-methyl amide group of a series of benzoxazinones with small heterocyclic rings has led to novel series of fused tricyclic benzoxazines which are potent 5-HT(1A/B/D) receptor antagonists with and w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::db3e73771267ce95dfc8d88c85ab0a7e
https://pubmed.ncbi.nlm.nih.gov/20590088
https://pubmed.ncbi.nlm.nih.gov/20590088
Autor:
Daniele Andreotti, Letizia Bettelini, Anna Checchia, Alessandro Zocchi, Beatrice Oliosi, Luca Tarsi, Emiliangelo Ratti, Filippo Visentini, Ilaria Sartori, Simone Spada, Carla Marchioro, Giorgio Bonanomi, Emilio Merlo-Pich, Elettra Fazzolari, Romano Di Fabio, Mauro Corsi, Stefano Fontana, Simone Braggio, Barbara Bertani, Roberto Benedetti, Michela Bettati, Paolo Cavanni, Kevin D. Read, Giovanna Tedesco, Maja Roscic, Silvia Terreni, Fabrizio Micheli, Roberto Arban, Laura Zonzini, Michele Negri, Renzo Carletti
Publikováno v:
Journal of medicinal chemistry. 53(13)
A pharmacophore model for triple reuptake inhibitors and the new class of 1-(aryl)-6-[alkoxyalkyl]-3- azabicyclo[3.1.0]hexanes were recently reported. Further investigation in this area led to the identification of a new series of potent and selectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6065c75cf3b0fac2702515c5ed7e7278
https://pubmed.ncbi.nlm.nih.gov/20527970
https://pubmed.ncbi.nlm.nih.gov/20527970
Autor:
Roberto Arban, Fabrizio Micheli, Silvia Davalli, Letizia Bettelini, Michele Negri, Carla Marchioro, Romano Di Fabio, Ilaria Sartori, Laura Zonzini, Barbara Bertani, Roberto Benedetti, Michela Bettati, Stefano Fontana, Giorgio Bonanomi, Doug Minick, Simone Braggio, Paolo Cavanni, Elettra Fazzolari, Anna Checchia, Alessandro Zocchi, Filippo Visentini, Kevin D. Read, Beatrice Oliosi, Giovanna Tedesco, Silvia Terreni, Luca Tarsi
Publikováno v:
Journal of medicinal chemistry. 53(6)
The discovery of new highly potent and selective triple reuptake inhibitors is reported. The new classes of 1-(aryl)-6-[alkoxyalkyl]-3-azabicyclo[3.1.0]hexanes and 6-(aryl)-6-[alkoxyalkyl]-3-azabicyclo[3.1.0]hexanes are described together with detail
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2556c284c9594a624f75bb7c11524b98
https://pubmed.ncbi.nlm.nih.gov/20170186
https://pubmed.ncbi.nlm.nih.gov/20170186