Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Ilaria Piga"'
Autor:
Daniele Boso, Martina Tognon, Matteo Curtarello, Sonia Minuzzo, Ilaria Piga, Valentina Brillo, Elisabetta Lazzarini, Jessica Carlet, Ludovica Marra, Chiara Trento, Andrea Rasola, Ionica Masgras, Leonardo Caporali, Fabio Del Ben, Giulia Brisotto, Matteo Turetta, Roberta Pastorelli, Laura Brunelli, Filippo Navaglia, Giovanni Esposito, Angela Grassi, Stefano Indraccolo
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-19 (2023)
Abstract Background Genetic and metabolic heterogeneity are well-known features of cancer and tumors can be viewed as an evolving mix of subclonal populations, subjected to selection driven by microenvironmental pressures or drug treatment. In previo
Externí odkaz:
https://doaj.org/article/291e0ae6448e4b3eb631add9fd1a77cb
Autor:
Ilaria Piga, Martina Verza, Francesca Montenegro, Giorgia Nardo, Elisabetta Zulato, Tiziana Zanin, Paola Del Bianco, Giovanni Esposito, Stefano Indraccolo
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Metabolic profiling of cancer is a rising interest in the field of biomarker development. One bottleneck of its clinical exploitation, however, is the lack of simple and quantitative techniques that enable to capture the key metabolic traits of tumor
Externí odkaz:
https://doaj.org/article/ab3953097d8b4812b78e1c5823dacdb4
Autor:
Carolina Venturoli, Ilaria Piga, Matteo Curtarello, Martina Verza, Giovanni Esposito, Santina Venuto, Filippo Navaglia, Angela Grassi, Stefano Indraccolo
Publikováno v:
Cells, Vol 10, Iss 2, p 325 (2021)
Pyruvate dehydrogenase kinase 1 (PDK1) blockade triggers are well characterized in vitro metabolic alterations in cancer cells, including reduced glycolysis and increased glucose oxidation. Here, by gene expression profiling and digital pathology-med
Externí odkaz:
https://doaj.org/article/674cbaadc7e14a9dbf7d91be3807fe5d
Autor:
Giuseppe Lombardi, Vittorina Zagonel, Ivan Lolli, Simona Rizzato, Toni Ibrahim, Alba Ariela Brandes, Roberta Rudà, Marica Eoli, Marina Paola Gardiman, Marco Pizzi, Paola Del Bianco, Ilaria Piga, Giovanni Esposito, Mario Caccese, Martina Verza, Gian Luca De Salvo, Stefano Indraccolo
Immunohistochemical staining of pACC in three representative GBM samples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13343542f57225be5c325c87138537c9
https://doi.org/10.1158/1078-0432.22477800.v1
https://doi.org/10.1158/1078-0432.22477800.v1
Autor:
Giuseppe Lombardi, Vittorina Zagonel, Ivan Lolli, Simona Rizzato, Toni Ibrahim, Alba Ariela Brandes, Roberta Rudà, Marica Eoli, Marina Paola Gardiman, Marco Pizzi, Paola Del Bianco, Ilaria Piga, Giovanni Esposito, Mario Caccese, Martina Verza, Gian Luca De Salvo, Stefano Indraccolo
Digital pathology raw data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::303d3b5b3b2584c0d3aa9e228fe6e7fe
https://doi.org/10.1158/1078-0432.22477791
https://doi.org/10.1158/1078-0432.22477791
Autor:
Jesper V. Olsen, Lars J. Jensen, Kim Theilgaard-Mönch, Stephen C. Blacklow, Vidyasiri Vemulapalli, Kristian Reckzeh, Ilaria Piga, Marie Locard-Paulet, Giulia Franciosa, Anamarija Pfeiffer
Supplementary Data from Phosphorylation of SHP2 at Tyr62 Enables Acquired Resistance to SHP2 Allosteric Inhibitors in FLT3-ITD–Driven AML
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e44e4fc3515e4df0e347ed1a54c643c
https://doi.org/10.1158/0008-5472.22430284
https://doi.org/10.1158/0008-5472.22430284
Autor:
Jesper V. Olsen, Lars J. Jensen, Kim Theilgaard-Mönch, Stephen C. Blacklow, Vidyasiri Vemulapalli, Kristian Reckzeh, Ilaria Piga, Marie Locard-Paulet, Giulia Franciosa, Anamarija Pfeiffer
The protein tyrosine phosphatase SHP2 is crucial for oncogenic transformation of acute myeloid leukemia (AML) cells expressing mutated receptor tyrosine kinases. SHP2 is required for full RAS-ERK activation to promote cell proliferation and survival
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78e5a2bf99c8efb8cfecfca5df859849
https://doi.org/10.1158/0008-5472.c.6513577.v1
https://doi.org/10.1158/0008-5472.c.6513577.v1
Autor:
Giuseppe Lombardi, Vittorina Zagonel, Ivan Lolli, Simona Rizzato, Toni Ibrahim, Alba Ariela Brandes, Roberta Rudà, Marica Eoli, Marina Paola Gardiman, Marco Pizzi, Paola Del Bianco, Ilaria Piga, Giovanni Esposito, Mario Caccese, Martina Verza, Gian Luca De Salvo, Stefano Indraccolo
Purpose:Preclinical studies show that antiangiogenic therapy exacerbates tumor glycolysis and activates liver kinase B1/AMP kinase (AMPK), a pathway involved in the regulation of tumor metabolism. We investigated whether certain metabolism-related in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::094152b55ba59b9fa0ba64a8ba6ee8c1
https://doi.org/10.1158/1078-0432.c.6529758
https://doi.org/10.1158/1078-0432.c.6529758
Autor:
Jesper V. Olsen, Lars J. Jensen, Kim Theilgaard-Mönch, Stephen C. Blacklow, Vidyasiri Vemulapalli, Kristian Reckzeh, Ilaria Piga, Marie Locard-Paulet, Giulia Franciosa, Anamarija Pfeiffer
Supplementary Table from Phosphorylation of SHP2 at Tyr62 Enables Acquired Resistance to SHP2 Allosteric Inhibitors in FLT3-ITD–Driven AML
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3670270ef0f89fb2bad014be2a715886
https://doi.org/10.1158/0008-5472.22430254.v1
https://doi.org/10.1158/0008-5472.22430254.v1
Autor:
Jesper V. Olsen, Lars J. Jensen, Kim Theilgaard-Mönch, Stephen C. Blacklow, Vidyasiri Vemulapalli, Kristian Reckzeh, Ilaria Piga, Marie Locard-Paulet, Giulia Franciosa, Anamarija Pfeiffer
Supplementary Figure from Phosphorylation of SHP2 at Tyr62 Enables Acquired Resistance to SHP2 Allosteric Inhibitors in FLT3-ITD–Driven AML
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21a286fc679490997ba56e2737835e74
https://doi.org/10.1158/0008-5472.22430278
https://doi.org/10.1158/0008-5472.22430278