Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Ilaria Piazza"'
Autor:
Agnese De Mario, Elisabetta Trevellin, Ilaria Piazza, Vincenzo Vindigni, Mirto Foletto, Rosario Rizzuto, Roberto Vettor, Cristina Mammucari
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Obesity is associated with increased risk and worse prognosis of many tumours including those of the breast and of the esophagus. Adipokines released from the peritumoural adipose tissue promote the metastatic potential of cancer cells, sugg
Externí odkaz:
https://doaj.org/article/5720cdba0a8f44059227b045cffce8da
Autor:
Giulia Di Marco, Gaia Gherardi, Agnese De Mario, Ilaria Piazza, Martina Baraldo, Andrea Mattarei, Bert Blaauw, Rosario Rizzuto, Diego De Stefani, Cristina Mammucari
Publikováno v:
Cell Death and Disease, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract MitoKATP is a channel of the inner mitochondrial membrane that controls mitochondrial K+ influx according to ATP availability. Recently, the genes encoding the pore-forming (MITOK) and the regulatory ATP-sensitive (MITOSUR) subunits of mitoK
Externí odkaz:
https://doaj.org/article/66b3a56db4114e61b4f290a6a6068a1f
Autor:
Emil Sporre, Jan Karlsen, Karen Schriever, Johannes Asplund-Samuelsson, Markus Janasch, Linnéa Strandberg, Anna Karlsson, David Kotol, Luise Zeckey, Ilaria Piazza, Per-Olof Syrén, Fredrik Edfors, Elton P. Hudson
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
Abstract Metabolite-level regulation of enzyme activity is important for microbes to cope with environmental shifts. Knowledge of such regulations can also guide strain engineering for biotechnology. Here we apply limited proteolysis-small molecule m
Externí odkaz:
https://doaj.org/article/2c6980d3398e4e32bbf83c4737c7e657
Autor:
Bingnan Li, Patrice Zeis, Yujie Zhang, Alisa Alekseenko, Eliska Fürst, Yerma Pareja Sanchez, Gen Lin, Manu M. Tekkedil, Ilaria Piazza, Lars M. Steinmetz, Vicent Pelechano
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Transcriptional memory is key for cellular adaptation. Here the authors show that differences in mRNA stability and mRNA degradation machinery between naïve and primed cells facilitate faster gene expression response to repeated stimuli.
Externí odkaz:
https://doaj.org/article/07c6c17a87b14297806ea44f76865958
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 7, Pp 1-5 (2021)
Graphical Abstract While informative, protein amounts and physical protein associations do not provide a full picture of protein function. This Commentary highlights the potential of structural and stability proteomic technologies to derive new insig
Externí odkaz:
https://doaj.org/article/62673b688c77484eaabbf4233c87050b
Autor:
Ilaria Piazza, Nigel Beaton, Roland Bruderer, Thomas Knobloch, Crystel Barbisan, Lucie Chandat, Alexander Sudau, Isabella Siepe, Oliver Rinner, Natalie de Souza, Paola Picotti, Lukas Reiter
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Proteomics is often used to map protein-drug interactions but identifying a drug’s protein targets along with the binding interfaces has not been achieved yet. Here, the authors integrate limited proteolysis and machine learning for the proteome-wi
Externí odkaz:
https://doaj.org/article/871b54abd526490392ac0a0d980afcf1
Autor:
Antonio Vitale, Giulio Cavalli, Piero Ruscitti, Jurgen Sota, Serena Colafrancesco, Roberta Priori, Guido Valesini, Lorenza Maria Argolini, Elena Baldissera, Elena Bartoloni, Daniele Cammelli, Giovanni Canestrari, Elena Cavallaro, Maria Grazia Massaro, Paola Cipriani, Ginevra De Marchi, Salvatore De Vita, Giacomo Emmi, Micol Frassi, Roberto Gerli, Elisa Gremese, Florenzo Iannone, Marco Fornaro, Anna Paladini, Giuseppe Lopalco, Raffaele Manna, Alessandro Mathieu, Carlomaurizio Montecucco, Marta Mosca, Ilaria Piazza, Matteo Piga, Irene Pontikaki, Micol Romano, Silvia Rossi, Maurizio Rossini, Elena Silvestri, Chiara Stagnaro, Rosaria Talarico, Bruno Frediani, Angela Tincani, Ombretta Viapiana, Gianfranco Vitiello, Paola Galozzi, Paolo Sfriso, Carla Gaggiano, Salvatore Grosso, Donato Rigante, Lorenzo Dagna, Roberto Giacomelli, Luca Cantarini
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
Background: Aim of this study was to search for any difference in the outcome of patients with adult onset Still's disease (AOSD) treated with anakinra (ANK) in relation with the interval between disease onset and the start of anti-interleukin(IL)-1
Externí odkaz:
https://doaj.org/article/e19a5a8db9ca43599cf794994b438ad4
Autor:
Antonio Vitale, Giulio Cavalli, Serena Colafrancesco, Roberta Priori, Guido Valesini, Lorenza Maria Argolini, Elena Baldissera, Elena Bartoloni, Daniele Cammelli, Giovanni Canestrari, Jurgen Sota, Elena Cavallaro, Maria Grazia Massaro, Piero Ruscitti, Paola Cipriani, Ginevra De Marchi, Salvatore De Vita, Giacomo Emmi, Gianfranco Ferraccioli, Micol Frassi, Roberto Gerli, Elisa Gremese, Florenzo Iannone, Giovanni Lapadula, Giuseppe Lopalco, Raffaele Manna, Alessandro Mathieu, Carlomaurizio Montecucco, Marta Mosca, Ilaria Piazza, Matteo Piga, Irene Pontikaki, Micol Romano, Silvia Rossi, Maurizio Rossini, Elena Silvestri, Chiara Stagnaro, Rosaria Talarico, Angela Tincani, Ombretta Viapiana, Gianfranco Vitiello, Paola Galozzi, Paolo Sfriso, Carla Gaggiano, Donato Rigante, Lorenzo Dagna, Roberto Giacomelli, Luca Cantarini
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Background: Anakinra (ANA) is an effective treatment choice in patients with adult onset Still’s disease (AOSD). Variables affecting treatment survival include loss of efficacy or adverse events, but also the decision to discontinue treatment after
Externí odkaz:
https://doaj.org/article/5f840fe673074997878f6a7e7014af2a
Autor:
Serena Colafrancesco, Roberta Priori, Guido Valesini, Lorenza Argolini, Elena Baldissera, Elena Bartoloni, Daniele Cammelli, Giovanni Canestrari, Luca Cantarini, Elena Cavallaro, Giulio Cavalli, Lucia Cerrito, Paola Cipriani, Lorenzo Dagna, Ginevra De Marchi, Salvatore De Vita, Giacomo Emmi, Gianfranco Ferraccioli, Micol Frassi, Mauro Galeazzi, Roberto Gerli, Roberto Giacomelli, Elisa Gremese, Florenzo Iannone, Giovanni Lapadula, Giuseppe Lopalco, Raffaele Manna, Alessandro Mathieu, Carlomaurizio Montecucco, Marta Mosca, Ilaria Piazza, Matteo Piga, Irene Pontikaki, Micol Romano, Silvia Rossi, Maurizio Rossini, Piero Ruscitti, Elena Silvestri, Chiara Stagnaro, Rosaria Talarico, Angela Tincani, Ombretta Viapiana, Gianfranco Vitiello, Francesca Fabris, Sara Bindoli, Leonardo Punzi, Paola Galozzi, Paolo Sfriso
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Background: Interleukin (IL)-1 plays a crucial role in the pathogenesis of Adult onset Still’s disease (AOSD).Objectives: To evaluate the efficacy and safety of anakinra (ANA) and canakinumab (CAN) in a large group of AOSD patients.Methods: Data on
Externí odkaz:
https://doaj.org/article/4f46a00649ad441a95e26aabd92e349d
Autor:
Liliana Malinovska, Valentina Cappelletti, Devon Kohler, Ilaria Piazza, Tsung-Heng Tsai, Monika Pepelnjak, Patrick Stalder, Christian Dörig, Fabian Sesterhenn, Franziska Elsässer, Lucie Kralickova, Nigel Beaton, Lukas Reiter, Natalie de Souza, Olga Vitek, Paola Picotti
Publikováno v:
Nature Protocols.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::588873eb24bac1853873477ec4be21f1
https://doi.org/10.1038/s41596-023-00808-9
https://doi.org/10.1038/s41596-023-00808-9