Magneto-Liposomes as MRI Contrast Agents: A Systematic Study of Different Liposomal Formulations

Autor: Nina Kostevšek, Calvin C. L. Cheung, Igor Serša, Mateja Erdani Kreft, Ilaria Monaco, Mauro Comes Franchini, Janja Vidmar, Wafa T. Al-Jamal

Publikováno v: Nanomaterials, Vol 10, Iss 5, p 889 (2020)

The majority of the clinically approved iron oxide nanoparticles (IO NPs) used as contrast agents for magnetic resonance imaging (MRI) have been withdrawn from the market either due to safety concerns or lack of profits. To address this challenge, li

Externí odkaz: https://doaj.org/article/ad98245a89db4b2a816b3802c0f9eaf7

PD1 blockade potentiates the therapeutic efficacy of photothermally-activated and MRI-guided low temperature-sensitive magnetoliposomes

Autor: Stephen R. Meech, Samo Hudoklin, Amalia Ruiz, Matthew Barker, Janez Ščančar, Guanglong Ma, Mauro Comes Franchini, Hatem A.F.M. Hassan, Mateja Erdani Kreft, Nina Kostevšek, Katarina Marković, Bostjan Markelc, Wafa' T Al-Jamal, Calvin C L Cheung, Andrew G. Mayes, Ilaria Monaco, Christopher R. Hall, Igor Serša, Maja Čemažar, Jamie Conyard

Publikováno v: Ma, G, Kostevšek, N, Monaco, I, Ruiz, A, Markelc, B, Cheung, C C L, Hudoklin, S, Kreft, M E, Hassan, H A F M, Barker, M, Conyard, J, Hall, C, Meech, S, Mayes, A G, Serša, I, Čemažar, M, Marković, K, Ščančar, J, Franchini, M C & Al-Jamal, W T 2021, ' PD1 blockade potentiates the therapeutic efficacy of photothermally-activated and MRI-guided low temperature-sensitive magnetoliposomes ', Journal of controlled release : official journal of the Controlled Release Society, vol. 332, pp. 419-433 . https://doi.org/10.1016/j.jconrel.2021.03.002

This study investigates the effect of PD1 blockade on the therapeutic efficacy of novel doxorubicin-loaded temperature-sensitive liposomes. Herein, we report photothermally-activated, low temperature-sensitive magnetoliposomes (mLTSL) for efficient d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::763a5a1fc9628b176d5ed4ed35b0f182
https://pure.qub.ac.uk/en/publications/51a5fbe4-6686-4fe9-bbd3-b68993ada4a1

One-pot synthesis of magnesium nanoparticles embedded in a chitosan microparticle matrix: a highly biocompatible tool for in vivo cancer treatment

Autor: Roberto Pini, Robert C.G. Martin, Mauro Comes Franchini, Yan Li, Guozhen Cui, Suping Li, Martina Banchelli, Erica Locatelli, Paolo Matteini, Ilaria Monaco

Publikováno v: Journal of Materials Chemistry B 4 (2016): 207–211. doi:10.1039/c5tb02499d
info:cnr-pdr/source/autori:Martin R.C.; Locatelli E.; Li Y.; Matteini P.; Monaco I.; Cui G.; Li S.; Banchelli M.; Pini R.; Comes Franchini M./titolo:One-pot synthesis of magnesium nanoparticles embedded in a chitosan microparticle matrix: A highly biocompatible tool for in vivo cancer treatment/doi:10.1039%2Fc5tb02499d/rivista:Journal of Materials Chemistry B/anno:2016/pagina_da:207/pagina_a:211/intervallo_pagine:207–211/volume:4

A novel highly biocompatible nanosystem made up of a chitosan matrix and filled with magnesium nanoparticles was synthesized using a simple and one-pot strategy, and tested as a promising, well-tolerated tool for photothermal therapy. Moreover, in vi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5955ea917c3a10cbb5611652cc08e0ea
https://pubmed.ncbi.nlm.nih.gov/32263362

Soft Piezoionic/Piezoelectric Nanocomposites Based on Ionogel/BaTiO 3 Nanoparticles for Low Frequency and Directional Discriminative Pressure Sensing

Autor: Cristina Lenardi, Ilaria Monaco, Sara Villa, Vittorio Massimo Mazzola, Erica Locatelli, Mauro Comes Franchini, Lorenzo Migliorini, Paolo Milani, Tommaso Santaniello, Mirko Maturi

We report on the fabrication and electro-mechanical characterization of a nanocomposite system exhibiting anisotropic electrical response under the application of tactile compressive stresses (5 kPa) at low frequencies (0.1-1 Hz). The nanocomposite i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6876ccd5b4929ba61bf5801d607ffeec
http://hdl.handle.net/11585/691093

Nanoprecipitation preparation of low temperature-sensitive magnetoliposomes

Autor: Nina Kostevšek, Calvin C L Cheung, Ilaria Monaco, Mauro Comes Franchini, Wafa' T Al-Jamal

Publikováno v: Cheung, C C L, Monaco, I, Kostevšek, N & Al-Jamal, W T 2020, ' Nanoprecipitation preparation of low temperature-sensitive magnetoliposomes ', COLLOIDS AND SURFACES B-BIOINTERFACES, pp. 111453 . https://doi.org/10.1016/j.colsurfb.2020.111453

Lysolipid-containing thermosensitive liposomes (LTSL) have gained attention for triggered release of chemotherapeutics. Superparamagnetic iron oxide nanoparticles (SPION) offers multimodal imaging and hyperthermia therapy opportunities as a promising

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1245125f7a0e79998c260cb64cc68e94
https://doi.org/10.1016/j.colsurfb.2020.111453