Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ilaria Malerba"'
Publikováno v:
Current Pharmaceutical Design. 11:1055-1065
In vitro clonogenic assays have been developed and widely used since many years to investigate the proliferation and the differentiation both of pluripotent haemopoietic stem cells (PHSC) and of the different progenitors of blood cell lineages: megak
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50b3e0370a2bb3e15b000e5f5ebc40a5
https://doi.org/10.2174/1381612053381648
https://doi.org/10.2174/1381612053381648
Autor:
Laura Gribaldo, Roberto Taramelli, Gerard Bowe, Ilaria Malerba, Marco Giorgio Bianchi, Francesco Acquati, Cristina Diodovich, Daniele Ferrario, Dominique Parent-Massin
Publikováno v:
Journal of Biochemical and Molecular Toxicology. 19:204-212
Acrylonitrile is a very high volume industrial chemical used primarily in the manufacture of plastics and rubber, which displays a pronounced acute toxicity and may be carcinogenic. The damage to the hematopoietic function by acrylonitrile may result
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dd4dafcfeeefe7fd78b2c713a67f1a4
https://doi.org/10.1002/jbt.20090
https://doi.org/10.1002/jbt.20090
Autor:
Laura Gribaldo, Roberto Taramelli, Francesco Acquati, Ilaria Malerba, Gerard Bowe, Cristina Diodovich, Dominique Parent-Massin, Marco Giorgio Bianchi
Publikováno v:
Journal of Biochemical and Molecular Toxicology. 17:286-294
In this study, the effect of naphthalene on the induction of apoptosis and gene expression profiles in cord blood cells has been evaluated, as well as its activity on the BCL-2 related protein expression. After 6, 24, and 48 h of exposure to naphthal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6c370462522e0405126fa2ba2857e8b
https://doi.org/10.1002/jbt.10091
https://doi.org/10.1002/jbt.10091
Autor:
Ilaria, Malerba
Publikováno v:
Giornale italiano di medicina del lavoro ed ergonomia. 33(3)
"REACH", "CLP" and "SDS" are Regulations that affect the rules on Health and Safety at Work and that, specifically, are linked to the chemical risk assessment. Up to 2015, the date when the old rules on Classification, Labeling and Packaging of hazar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2d2e12f322ab902533d4d0fd2987e5b2
https://pubmed.ncbi.nlm.nih.gov/22073671
https://pubmed.ncbi.nlm.nih.gov/22073671
Objective In vitro models of hematopoiesis used in investigative hematopathology and in safety studies on candidate drugs, involve clonogenic assays on colony-forming unit granulocyte macrophage (CFU-GM). These assays require live and unstained colon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55ecb51aabb22c072cf0b3d84b8b6356
http://hdl.handle.net/10281/4002
http://hdl.handle.net/10281/4002
Publikováno v:
SPIE Proceedings.
In order to evaluate the potential hematotoxicity of xenobiotics, including candidate anti-cancer drugs, in vitro models of hematopoiesis are used, which involve clonogenic assays on CFU-GM (Colony Forming Unit-Granulocyte-Macrophage). These assays r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce2809aa711425e0f4a8987b877b64b2
https://doi.org/10.1117/12.685110
https://doi.org/10.1117/12.685110
Autor:
Maria Carfì, P. Melchioretto, Cristian Pellizzer, Valentina Campi, Ilaria Malerba, Laura Gribaldo, Daniela Maurici, Cristina Diodovich, Luca Zoia, Chiara Urani, Marco Orlandi
Styrene is one of the most important monomers produced worldwide. IARC classified styrene as a possible carcinogen to humans (group 2B). Styrene-7,8-oxide (SO) is the main reactive metabolite of styrene, and it is found to be genotoxic in several in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::753b451ae9807a772250945b062bd1ff
http://hdl.handle.net/10281/4204
http://hdl.handle.net/10281/4204
Autor:
Loredana Bassi, Cristina Diodovich, Brighitta Eletti, Ilaria Malerba, Laura Gribaldo, Maria Grazia Sacco, Angelo Collotta
Publikováno v:
Experimental and molecular pathology. 79(3)
Cells derived from superficial and deep lymph nodes of transgenic mice in which CD40L expression was deregulated were grown in vitro. After 3 months of interleukin 3 or interleukin 12 stimulation, the cells remained interleukin-independent, showed th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8db7d389d14f1b06744f604078b348d
https://pubmed.ncbi.nlm.nih.gov/16226746
https://pubmed.ncbi.nlm.nih.gov/16226746
Autor:
Laura Gribaldo, C. Croera, Maria Bayo, Augusto Pessina, Loredana Cavicchini, Maria Grazia Neri, Ilaria Malerba, Laura Passardi
Publikováno v:
Alternatives to laboratory animals : ATLA. 32(1)
In a recent prevalidation study, the use of a methylcellulose colony-forming unit-granulocyte/macrophage (CFU-GM) macroassay for two independent in vitro tests (human and murine cell based) was suggested for quantifying the potential haematotoxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc6de73cb90a3d9df4bb7ae4b3ae9fa2
https://pubmed.ncbi.nlm.nih.gov/15603550
https://pubmed.ncbi.nlm.nih.gov/15603550
Autor:
Barbara Casati, Dominique Parent-Massin, Ilaria Malerba, Erminio Marafante, Daniele Ferrario, Cristina Diodovich, Laura Gribaldo
Publikováno v:
Archives of toxicology. 79(9)
The International Agency for Research on Cancer (IARC) currently lists tetrachloroethylene [perchloroethylene (PCE)] as being carcinogenic in animals. PCE is listed as possibly carcinogenic to humans upon occupational exposure. Human exposure to PCE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3e609340819e120c14c9e53a2576af7
https://pubmed.ncbi.nlm.nih.gov/16010555
https://pubmed.ncbi.nlm.nih.gov/16010555