Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Ilaria Frasson"'
Autor:
Giulia Sibille, Giuseppe Mannino, Ilaria Frasson, Marta Pavan, Anna Luganini, Cristiano Salata, Massimo E. Maffei, Giorgio Gribaudo
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7370 (2024)
The appearance of new respiratory virus infections in humans with epidemic or pandemic potential has underscored the urgent need for effective broad-spectrum antivirals (BSAs). Bioactive compounds derived from plants may provide a natural source of n
Externí odkaz:
https://doaj.org/article/9d5ff36b60434f41b6993d1f98f9a878
Autor:
Ilaria Frasson
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/8e5d0df8c9bb4817bcf438066d7066ad
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9523 (2023)
Guanine quadruplexes (G4s) are non-canonical nucleic acid structures formed by guanine (G)-rich tracts that assemble into a core of stacked planar tetrads. G4s are found in the human genome and in the genomes of human pathogens, where they are involv
Externí odkaz:
https://doaj.org/article/3ff7790470e74ee5b2660ca0bfb6f643
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Ilaria Frasson et al. find that the herpesvirus major transcription factor ICP4 regulates viral gene expression and replication through binding to parallel DNA G-quadruplexes (G4s). These results suggest that drugs targeting G4s at ICP4-regulated gen
Externí odkaz:
https://doaj.org/article/943c4355795a4746b380351fd6fd43ff
Autor:
Ilaria Caputo, Brasilina Caroccia, Ilaria Frasson, Elena Poggio, Stefania Zamberlan, Margherita Morpurgo, Teresa M. Seccia, Tito Calì, Marisa Brini, Sara N. Richter, Gian Paolo Rossi
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 5125 (2022)
Blockers of the renin-angiotensin system (RAS) have been reported to increase the angiotensin converting enzyme (ACE)2, the cellular receptor of SARS-CoV-2, and thus the risk and course of COVID-19. Therefore, we investigated if angiotensin (Ang) II
Externí odkaz:
https://doaj.org/article/e6c61b54e3534205a84eddd90ec744db
Autor:
Enrico Lavezzo, Michele Berselli, Ilaria Frasson, Rosalba Perrone, Giorgio Palù, Alessandra R Brazzale, Sara N Richter, Stefano Toppo
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 12, p e1006675 (2018)
G-quadruplexes are non-canonical nucleic-acid structures that control transcription, replication, and recombination in organisms. G-quadruplexes are present in eukaryotes, prokaryotes, and viruses. In the latter, mounting evidence indicates their key
Externí odkaz:
https://doaj.org/article/c648b46eb4964041aafca1d8e2d27290
Publikováno v:
Molecules, Vol 24, Iss 13, p 2375 (2019)
Human Alphaherpesviruses comprise three members, herpes simplex virus (HSV) 1 and 2 and varicella zoster virus (VZV). These viruses are characterized by a lytic cycle in epithelial cells and latency in the nervous system, with lifelong infections tha
Externí odkaz:
https://doaj.org/article/e33d5219bb8c477fb1af96fe5e8cbb2a
Autor:
Andrea Bartolini, Ilaria Frasson, Maria Angela Biasolo, Ettore De Canale, Tiziana Tommasini, Caterina Boldrin, Lucia Rossi, Sara N. Richter, Antonietta Cavallaro
Publikováno v:
Microbiologia Medica, Vol 28, Iss 1 (2013)
Introduction: In the management of nosocomial infections, the emergence of carbapenem-resistance in Enterobacteriaceae strains is a matter of increasing concern. The aim of this study was to detect and actively survey the presence of these strains by
Externí odkaz:
https://doaj.org/article/79c9e7d36f3448228b17ee7f161eaaac
Autor:
Rosalba Perrone, Matteo Nadai, Jerrod A Poe, Ilaria Frasson, Manlio Palumbo, Giorgio Palù, Thomas E Smithgall, Sara N Richter
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e73121 (2013)
G-quadruplexes are tetraplex structures of nucleic acids that can form in G-rich sequences. Their presence and functional role have been established in telomeres, oncogene promoters and coding regions of the human chromosome. In particular, they have
Externí odkaz:
https://doaj.org/article/24f856fea414412cadb23b059038d14d
Autor:
Emanuela Ruggiero, Ilaria Frasson, Elena Tosoni, Matteo Scalabrin, Rosalba Perrone, Maja Marušič, Janez Plavec, Sara N. Richter
Publikováno v:
ACS Infectious Diseases. 8:958-968
HIV-1 integrated long terminal repeat (LTR) promoter activity is modulated by folding of its G-rich region into non-canonical nucleic acids structures, such as G-quadruplexes (G4s), and their interaction with cellular proteins. Here, by a combined pu