Výsledky vyhledávání - "Ilaria Francesca Rizzuti"

Akademický článek

Optimizing the Pharmacological Properties of Discoidal Polymeric Nanoconstructs Against Triple-Negative Breast Cancer Cells

Autor: Miguel Ferreira, Ilaria Francesca Rizzuti, Anna Lisa Palange, Maria Grazia Barbato, Valentina Di Francesco, Martina Di Francesco, Paolo Decuzzi

Publikováno v: Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)

Fine-tuning loading and release of therapeutic and imaging agents associated with polymeric matrices is a fundamental step in the preclinical development of novel nanomedicines. Here, 1,000 × 400 nm Discoidal Polymeric Nanoconstructs (DPNs) were rea

Externí odkaz: https://doaj.org/article/080d19b7343649c381079388aab81441

Zobrazit plný text záznamu

Mechanical Control of Cell Proliferation Increases Resistance to Chemotherapeutic Agents

Autor: Ilaria Francesca Rizzuti, Zacchari Ben-Meriem, Catherine Barentin, Hélène Delanoë-Ayari, Haralampos Hatzikirou, Julie Guillermet-Guibert, Silvia Arcucci, Morgan Delarue, Audrey Prunet, Charlotte Rivière, Pietro Mascheroni

Publikováno v: Physical review letters
United States
Physical Review Letters
Physical Review Letters, American Physical Society, 2020, 125 (12), pp.128103. ⟨10.1103/PhysRevLett.125.128103⟩
Physical Review Letters, 2020, 125 (12), pp.128103. ⟨10.1103/PhysRevLett.125.128103⟩

International audience; While many cellular mechanisms leading to chemotherapeutic resistance have been identified, there is an increasing realization that tumor-stroma interactions also play an important role. In particular, mechanical alterations a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6b4a514e5e56a488e45c06674d7a713
https://hdl.handle.net/10033/622533

Zobrazit plný text záznamu

Optimizing the Pharmacological Properties of Discoidal Polymeric Nanoconstructs Against Triple-Negative Breast Cancer Cells

Autor: Valentina Di Francesco, Martina Di Francesco, Miguel Ferreira, Maria Grazia Barbato, Ilaria Francesca Rizzuti, Anna Lisa Palange, Paolo Decuzzi

Publikováno v: Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Frontiers in Bioengineering and Biotechnology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72b0b30f6364831bdcbc9555e01ef2fc
https://doi.org/10.3389/fbioe.2020.00005

Zobrazit plný text záznamu

Deformable Discoidal Polymeric Nanoconstructs for the Precise Delivery of Therapeutic and Imaging Agents

Autor: Ilaria Francesca Rizzuti, Anna Lisa Palange, Miguel Ferreira, Paolo Decuzzi, Roberto Palomba

Publikováno v: Molecular Therapy. 25:1514-1521

Over the last 15 years, a plethora of materials and different formulations have been proposed for the realization of nanomedicines. Yet drug-loading efficiency, sequestration by phagocytic cells, and tumor accumulation are sub-optimal. This would imp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::555bc05a9a34630d7350417511e9b2fa
https://doi.org/10.1016/j.ymthe.2017.02.012

Zobrazit plný text záznamu

A tissue chamber chip for assessing nanoparticle mobility in the extravascular space

Autor: Rui Perreira, Martí Duocastella, Paolo Zunino, Roberto Palomba, Paolo Decuzzi, Thomas Moore, Valeria Lusi, Miguel Ferreira, Dan Peer, Shoshy Mizrahy, Federica Laurino, Ilaria Francesca Rizzuti, Alessandro Coclite

Although a plethora of nanoparticle configurations have been proposed over the past 10 years, the uniform and deep penetration of systemically injected nanomedicines into the diseased tissue stays as a major biological barrier. Here, a ‘Tissue Cham

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3d75c7d5b3f1c4e1bccd5663ade9eac
http://hdl.handle.net/11589/213200

Zobrazit plný text záznamu

Modulating Phagocytic Cell Sequestration by Tailoring Nanoconstruct Softness

Autor: Paolo Decuzzi, Maria Grazia Barbato, Claudio Canale, Antonio Cervadoro, Ilaria Francesca Rizzuti, Miguel Ferreira, Anna Lisa Palange, Roberto Palomba

Publikováno v: ACS nano. 12(2)

The effect of nanoparticle size, shape, and surface properties on cellular uptake has been extensively investigated for its basic science and translational implications. Recently, softness is emerging as a design parameter for modulating the interact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37aa66f284de37e7f92ca5f259e444de
https://pubmed.ncbi.nlm.nih.gov/29314819

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání