Výsledky vyhledávání - "Ilaria Devito"

Akademický článek

Inhibition of Nipah virus infection in vivo: targeting an early stage of paramyxovirus fusion activation during viral entry.

Autor: Matteo Porotto, Barry Rockx, Christine C Yokoyama, Aparna Talekar, Ilaria Devito, Laura M Palermo, Jie Liu, Riccardo Cortese, Min Lu, Heinz Feldmann, Antonello Pessi, Anne Moscona

Publikováno v: PLoS Pathogens, Vol 6, Iss 10, p e1001168 (2010)

In the paramyxovirus cell entry process, receptor binding triggers conformational changes in the fusion protein (F) leading to viral and cellular membrane fusion. Peptides derived from C-terminal heptad repeat (HRC) regions in F have been shown to in

Externí odkaz: https://doaj.org/article/7321bb26fcdb44f9915cb3eae907aa3e

Zobrazit plný text záznamu

Immune-Onco-Microbiome: A New Revolution for Gynecological Cancers

Autor: Chiara Di Tucci, Ludovico Muzii, Ilaria DeVito

Publikováno v: Biomedicines. 11:782

Despite significant advances in understanding the pathogenetic mechanisms underlying gynaecological cancers, these cancers still remain widespread. Recent research points to a possible link between microbiota and cancer, and the most recent attention

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7885e23ba8c9eaf180dbfeb8b148816f
https://doi.org/10.3390/biomedicines11030782

Zobrazit plný text záznamu

Abstract LB130: High-throughput RNA sequencing directly from cell lysates enables reproducible phenotypic profiling for assessing novel compounds and treatments in cancer research

Autor: Andrea O'Hara, Michael Stephens, Ilaria DeVito, Laure Turner, Christopher Mozdzierz, Haythem Latif, Ginger Zhou

Publikováno v: Cancer Research. 82:LB130-LB130

New oncology therapies are driven by multiple approaches, with a heavy emphasis on small-molecule therapeutics to target cancer cells and provide a therapeutic benefit to cancer patients. These small-molecule compounds can be used as a stand-alone tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c636a7151098891a319d7cb9d9872f5b
https://doi.org/10.1158/1538-7445.am2022-lb130

Zobrazit plný text záznamu

Prevention of Measles Virus Infection by Intranasal Delivery of Fusion Inhibitor Peptides

Autor: Eric M. Jurgens, Ilaria DeVito, D. Huey, Cyrille Mathieu, Matteo Porotto, Branka Horvat, Stefan Niewiesk, Jeremy Charles Welsch, Aparna Talekar, Anne Moscona

Publikováno v: Journal of Virology
Journal of Virology, American Society for Microbiology, 2015, 89 (2), pp.1143-1155. ⟨10.1128/JVI.02417-14⟩
Journal of Virology, 2015, 89 (2), pp.1143-1155. ⟨10.1128/JVI.02417-14⟩

Measles virus (MV) infection is undergoing resurgence and remains one of the leading causes of death among young children worldwide despite the availability of an effective measles vaccine. MV infects its target cells by coordinated action of the MV

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b5ea17a4cd7b493fd109ae26c4a0f8d
https://doi.org/10.1128/jvi.02417-14

Zobrazit plný text záznamu

Identification of a Region in the Stalk Domain of the Nipah Virus Receptor Binding Protein That Is Critical for Fusion Activation

Autor: Aparna Talekar, Ian A. Wilson, Zuhair Salah, Anasuya Chattopadhyay, Anne Moscona, John K. Rose, Matteo Porotto, Rui Xu, Ilaria DeVito, Samantha G. Palmer

Publikováno v: Journal of Virology. 87:10980-10996

Paramyxoviruses, including the emerging lethal human Nipah virus (NiV) and the avian Newcastle disease virus (NDV), enter host cells through fusion of the viral and target cell membranes. For paramyxoviruses, membrane fusion is the result of the conc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f209efaeea35e93fa509f42942596fb0
https://doi.org/10.1128/jvi.01646-13

Zobrazit plný text záznamu

The Second Receptor Binding Site of the Globular Head of the Newcastle Disease Virus Hemagglutinin-Neuraminidase Activates the Stalk of Multiple Paramyxovirus Receptor Binding Proteins To Trigger Fusion

Autor: Ian A. Wilson, Rui Xu, Samantha G. Palmer, Anne Moscona, Matteo Porotto, Ilaria DeVito, Aparna Talekar, Zuhair Salah

Publikováno v: Journal of Virology. 86:5730-5741

The hemagglutinin-neuraminidase (HN) protein of paramyxoviruses carries out three distinct activities contributing to the ability of HN to promote viral fusion and entry: receptor binding, receptor cleavage (neuraminidase), and activation of the fusi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::258e6cbc7a3ff810e4f45c2241992941
https://doi.org/10.1128/jvi.06793-11

Zobrazit plný text záznamu

Regulation of Paramyxovirus Fusion Activation: the Hemagglutinin-Neuraminidase Protein Stabilizes the Fusion Protein in a Pretriggered State

Autor: Zuhair Salah, Long Gui, Laura M. Palermo, Matteo Porotto, Eric M. Jurgens, Anne Moscona, Christine C. Yokoyama, Kelly K. Lee, Ilaria DeVito, Hong Lu

The hemagglutinin (HA)-neuraminidase protein (HN) of paramyxoviruses carries out three discrete activities, each of which affects the ability of HN to promote viral fusion and entry: receptor binding, receptor cleaving (neuraminidase), and triggering

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bb15469c7f70d9c062dc349594abf22
https://europepmc.org/articles/PMC3497673/

Zobrazit plný text záznamu

Spring-loaded model revisited: Paramyxovirus fusion requires engagement of a receptor binding protein beyond initial triggering of the fusion protein

Autor: Eric M. Jurgens, Jia L. Yee, Antonello Pessi, Anne Moscona, Ilaria DeVito, Matteo Porotto, Christine C. Yokoyama, Samantha G. Palmer

During paramyxovirus entry into a host cell, receptor engagement by a specialized binding protein triggers conformational changes in the adjacent fusion protein (F), leading to fusion between the viral and cell membranes. According to the existing pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ef7777b60f6d96834ca13e015e69f9f
http://hdl.handle.net/11591/388656

Zobrazit plný text záznamu

Inhibition of Nipah Virus Infection In Vivo: Targeting an early stage of paramyxovirus fusion activation during viral entry

Autor: Heinz Feldmann, Aparna Talekar, Anne Moscona, Christine C. Yokoyama, Min Lu, Ilaria DeVito, Riccardo Cortese, Barry Rockx, Antonello Pessi, Matteo Porotto, Laura M. Palermo, Jie Liu

Publikováno v: PLoS Pathogens, Vol 6, Iss 10, p e1001168 (2010)
PLoS Pathogens

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f523c7e20c8d7a30bd2c5523a28166f7
http://hdl.handle.net/11591/388661

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání