Výsledky vyhledávání - "Ilaria Defilippi"

Akademický článek

Deferasirox is a powerful NF-κB inhibitor in myelodysplastic cells and in leukemia cell lines acting independently from cell iron deprivation by chelation and reactive oxygen species scavenging

Autor: Emanuela Messa, Sonia Carturan, Chiara Maffè, Marisa Pautasso, Enrico Bracco, Antonella Roetto, Francesca Messa, Francesca Arruga, Ilaria Defilippi, Valentina Rosso, Chiara Zanone, Antonia Rotolo, Elisabetta Greco, Rosa M. Pellegrino, Daniele Alberti, Giuseppe Saglio, Daniela Cilloni

Publikováno v: Haematologica, Vol 95, Iss 8 (2010)

Background Usefulness of iron chelation therapy in myelodysplastic patients is still under debate but many authors suggest its possible role in improving survival of low-risk myelodysplastic patients. Several reports have described an unexpected effe

Externí odkaz: https://doaj.org/article/f7fbab04fb544dbb84f3c3518933cf68

Zobrazit plný text záznamu

Akademický článek

Early prediction of treatment outcome in acute myeloid leukemia by measurement of WT1 transcript levels in peripheral blood samples collected after chemotherapy

Autor: Daniela Cilloni, Francesca Messa, Francesca Arruga, Ilaria Defilippi, Enrico Gottardi, Milena Fava, Sonia Carturan, Renata Catalano, Enrico Bracco, Emanuela Messa, Paolo Nicoli, Daniela Diverio, Miguel A. Sanz, Giovanni Martinelli, Francesco Lo-Coco, Giuseppe Saglio

Publikováno v: Haematologica, Vol 93, Iss 6 (2008)

The Wilms’ tumor gene WT1 is a reliable marker for minimal residual disease assessment in acute leukemia patients. The study was designed to demonstrate the potential use of WT1 to establish quality of remission in acute leukemia patients for early

Externí odkaz: https://doaj.org/article/34c73617a1824b768290173a34b6de06

Zobrazit plný text záznamu

Expression of vascular remodelling markers in relation to bradykinin receptors in asthma and COPD

Autor: Nick H. T. ten Hacken, Sabrina Benedetto, Virginia De Rose, Bruno Balbi, Federica Sabatini, Valentina Sorbello, Cesare Usai, Isabella Gnemmi, Wim Timens, Antonino Di Stefano, Ilaria Defilippi, Fabio Luigi Massimo Ricciardolo, Dirkje S. Postma, Loredana Petecchia

Publikováno v: Thorax, 68(9), 803-811. BMJ PUBLISHING GROUP

Vascular remodelling plays a central role in asthma and chronic obstructive pulmonary disease (COPD). Bradykinin (BK) is a vasoactive proinflammatory peptide mediating acute responses in asthma. We investigated the role of angiogenic factors in relat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae04b4a6d0945db3613811fe2ec1e080
https://hdl.handle.net/11370/63c909c3-3283-4056-b009-ff107f676093

Zobrazit plný text záznamu

Bradykinin- and lipopolysaccharide-induced bradykinin B2 receptor expression, interleukin 8 release and 'nitrosative stress' in bronchial epithelial cells BEAS-2B: Role for neutrophils

Autor: Andrea Robotti, Caterina Bucca, Gert Folkerts, Ilaria Defilippi, Dein C. van Renswouw, Fabio Luigi Massimo Ricciardolo, Sabrina Benedetto, Virginia De Rose, Federica Sabatini, Valentina Sorbello

Publikováno v: European Journal of Pharmacology. 694:30-38

Bradykinin-induced interleukin (IL)-8 release should potentially activate neutrophils releasing myeloperoxidase (MPO) and subsequently generating "nitrosative stress". We studied bradykinin-induced expression of bradykinin B(2) receptor and bradykini

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8329b6e50be8ab501350f6c1266aad0b
https://doi.org/10.1016/j.ejphar.2012.07.051

Zobrazit plný text záznamu

Comparison of 3 Tfr2-deficient murine models suggests distinct functions for Tfr2-α and Tfr2-β isoforms in different tissues

Autor: Clara Camaschella, Alessandro Bondi, Sonia Carturan, Daniela Cilloni, Rosa Maria Pellegrino, Ilaria Defilippi, Antonella Roetto, Fulvio Riondato, Giuseppe Saglio, Barbara Miniscalco, Lorenzo Silengo, Ferdinando Di Cunto, Ornellla Azzolino, Emilio Hirsch, Fiorella Altruda

Publikováno v: Blood. 115:3382-3389

Transferrin receptor 2 (TFR2) is a transmembrane protein that is mutated in hemochromatosis type 3. The TFR2 gene is transcribed in 2 main isoforms: the full-length (α) and a shorter form (β). α-Tfr2 is the sensor of diferric transferrin, implicat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca69c45186fd258e843475294f3f0831
https://doi.org/10.1182/blood-2009-09-240960

Zobrazit plný text záznamu

Valproate enhances imatinib-induced growth arrest and apoptosis in chronic myeloid leukemia cells

Autor: Daniela Cilloni, Giuseppe Saglio, Annalisa Chiarenza, Francesca Messa, Marisa Pautasso, Enrico Bracco, Renata Catalano, Enrico Gottardi, Angelo Guerrasio, Ilaria Defilippi, Alessandro Morotti, Francesca Arruga, Riccardo Taulli, Sonia Carturan, Valentina Rosso, Daniela Baraban, Chiara Pilatrino

Publikováno v: Cancer. 106:1188-1196

BACKGROUND The objective of this study was to evaluate the ability of the clinically available histone deacetylase (HDAC) inhibitor valproate to enhance the cytotoxicity of the Bcr-Abl inhibitor imatinib in imatinib-resistant cell lines. METHODS Inte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04ff008227b8260d07c619adaa850913
https://doi.org/10.1002/cncr.21725

Zobrazit plný text záznamu

The NF-κB pathway blockade by the IKK inhibitor PS1145 can overcome Imatinib resistance

Autor: Alessandro Morotti, Michele Baccarani, A Sen, Rosso, G. Saglio, Enrico Bracco, Daniela Cilloni, Francesca Arruga, Ilaria Defilippi, Emanuela Messa, Giovanni Martinelli, Sonia Carturan, Marisa Pautasso, Emilia Giugliano, Francesca Messa

Publikováno v: Leukemia. 20:61-67

Imatinib represents at present the most attractive therapy for BCR-ABL positive leukemias, even though a percentage of CML patients develop resistance to this compound. For these resistant patients a therapeutic approach based on a combination of dru

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ddd3205b4ac057d86b857adb1060860
https://doi.org/10.1038/sj.leu.2403998

Zobrazit plný text záznamu

Sensitivity to imatinib therapy may be predicted by testing Wilms tumor gene expression and colony growth after a short in vitro incubation

Autor: Milena Fava, Enrico Gottardi, Giovanna Rege-Cambrin, Giuseppe Saglio, Francesca Arruga, Emanuela Messa, Ilaria Defilippi, Daniela Cilloni, Francesca Messa, Sonia Carturan, Emilia Giugliano, Daniele Alberti, Alessandro Morotti, Michele Baccarani

Publikováno v: Cancer. 101:979-988

BACKGROUND The objective of the current study was to verify the ability to predict response to imatinib therapy using in vitro assays to evaluate the inhibition of Wilms tumor gene (WT1) expression and colony growth after samples obtained from patien

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9e0f4486ebb971f1ead31bf2a141c70
https://doi.org/10.1002/cncr.20457

Zobrazit plný text záznamu

WT1 overexpression: A clinically useful marker in acute and chronic myeloid leukemias

Autor: Giuseppe Saglio, Francesca Arruga, Sara Capella, Anna Marina Liberati, Daniela Cilloni, Maria Rauco, Ilaria Defilippi, Sara Grillo, Sonia Carturan, Valentina Rosso

Publikováno v: Hematology. 10:76-78

Monitoring of acute leukemia patients during and after treatment for the presence of remaining leukemic cells minimal residual disease (MRD) have been shown to give major insight into the effectiveness of treatment. However, so far applicability of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bd538c3aabfb8f0e7eabbecfe875bfd
https://doi.org/10.1080/10245330512331390005

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání