Monitoring EPR Effect Dynamics during Nanotaxane Treatment with Theranostic Polymeric Micelles

Autor: Ilaria Biancacci, Federica De Lorenzi, Benjamin Theek, Xiangyang Bai, Jan‐Niklas May, Lorena Consolino, Maike Baues, Diana Moeckel, Felix Gremse, Saskia vonStillfried, Asmaa El Shafei, Karina Benderski, Armin Azadkhah Shalmani, Alec Wang, Jeffrey Momoh, Quim Peña, Eva Miriam Buhl, Johannes Buyel, Wim Hennink, Fabian Kiessling, Josbert Metselaar, Yang Shi, Twan Lammers

Publikováno v: Advanced Science, Vol 9, Iss 10, Pp n/a-n/a (2022)

Abstract Cancer nanomedicines rely on the enhanced permeability and retention (EPR) effect for efficient target site accumulation. The EPR effect, however, is highly heterogeneous among different tumor types and cancer patients and its extent is expe

Externí odkaz: https://doaj.org/article/e176678c786847e28bbd7e7799858866

Imaging-assisted anticancer nanotherapy

Autor: Anshuman Dasgupta, Ilaria Biancacci, Twan Lammers, Fabian Kiessling

Publikováno v: Theranostics
Theranostics 10(3), 956-967 (2020). doi:10.7150/thno.38288

Theranostics 10(3), 956-967 (2020). doi:10.7150/thno.38288
Published by Ivyspring, Wyoming, NSW

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e81e3e51b8a4dd1d117d9395a5bd301
http://europepmc.org/articles/PMC6956808

Optical imaging of the whole-body to cellular biodistribution of clinical-stage PEG-b-pHPMA-based core-crosslinked polymeric micelles

Autor: Cristianne J.F. Rijcken, Ilaria Biancacci, Qingxue Sun, Gert Storm, Marielle Thewissen, Matthias Bartneck, Wim E. Hennink, Felix Gremse, Diana Möckel, Twan Lammers, Alexandros Marios Sofias, Fabian Kiessling, Qizhi Hu, Stefanie Rosenhain, Yang Shi

Publikováno v: Journal of controlled release, 328, 805-816. Elsevier
Journal of Controlled Release
Journal of controlled release : official journal of the Controlled Release Society, 328, 805. Elsevier
J Control Release

Core-crosslinked polymeric micelles (CCPM) based on PEG-b-pHPMA-lactate are clinically evaluated for the treatment of cancer. We macroscopically and microscopically investigated the biodistribution and target site accumulation of CCPM. To this end, f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbca1f64ec45e3d305b4d54ae389455b
https://research.utwente.nl/en/publications/094355e1-69e7-4851-ab8f-6c974b685a01

Monitoring EPR Effect Dynamics during Nanotaxane Treatment with Theranostic Polymeric Micelles.

Autor: Biancacci, Ilaria¹ (AUTHOR), De Lorenzi, Federica¹ (AUTHOR), Theek, Benjamin¹ (AUTHOR), Bai, Xiangyang¹ (AUTHOR), May, Jan‐Niklas¹ (AUTHOR), Consolino, Lorena¹ (AUTHOR), Baues, Maike¹ (AUTHOR), Moeckel, Diana¹ (AUTHOR), Gremse, Felix^1,2 (AUTHOR), von Stillfried, Saskia³ (AUTHOR), El Shafei, Asmaa¹ (AUTHOR), Benderski, Karina¹ (AUTHOR), Azadkhah Shalmani, Armin¹ (AUTHOR), Wang, Alec¹ (AUTHOR), Momoh, Jeffrey¹ (AUTHOR), Peña, Quim¹ (AUTHOR), Buhl, Eva Miriam⁴ (AUTHOR), Buyel, Johannes^5,6 (AUTHOR), Hennink, Wim⁷ (AUTHOR), Kiessling, Fabian^8,9 (AUTHOR)

Publikováno v: Advanced Science. Apr2022, Vol. 9 Issue 10, p1-9. 9p.

Intermittent Fasting Primes the Tumor Microenvironment and Improves Nanomedicine Delivery in Hepatocellular Carcinoma.

Autor: Becker, Svea, Momoh, Jeffrey, Biancacci, Ilaria, Möckel, Diana, Wang, Qingbi, May, Jan‐Niklas, Su, Huan, Candels, Lena Susanna, Berres, Marie‐Luise, Kiessling, Fabian, Hatting, Maximilian, Lammers, Twan, Trautwein, Christian

Publikováno v: Small; Oct2023, Vol. 19 Issue 43, p1-13, 13p