Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Ilaria, Pelizzoni"'
Autor:
Barbara, Bettegazzi, Ilaria, Pelizzoni, Floramarida, Salerno Scarzella, Lisa Michelle, Restelli, Daniele, Zacchetti, Francesca, Maltecca, Giorgio, Casari, Fabio, Grohovaz, Franca, Codazzi
Publikováno v:
Oxidative Medicine and Cellular Longevity
Several neurodegenerative disorders exhibit selective vulnerability, with subsets of neurons more affected than others, possibly because of the high expression of an altered gene or the presence of particular features that make them more susceptible
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::de6764d2675c68497ddc0a59d663b8e0
https://pubmed.ncbi.nlm.nih.gov/31781336
https://pubmed.ncbi.nlm.nih.gov/31781336
Autor:
Franca Codazzi, Barbara Bettegazzi, Fabio Grohovaz, Francesca Maltecca, Ilaria Pelizzoni, Lisa Michelle Restelli, Daniele Zacchetti, Giorgio Casari, Floramarida Salerno Scarzella
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2019 (2019)
Several neurodegenerative disorders exhibit selective vulnerability, with subsets of neurons more affected than others, possibly because of the high expression of an altered gene or the presence of particular features that make them more susceptible
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bb0f2ee62d7cc2f67bf7bdf6fb0dd10
Autor:
Elisabeth Mangiameli, Ilaria Pelizzoni, Franca Codazzi, Myriam Rai, Floramarida Salerno Scarzella, Amélie Hu, Massimo Pandolfo, Fabio Grohovaz, Simona Donatello
Publikováno v:
Human molecular genetics. 25(22)
We employed induced pluripotent stem cell (iPSC)-derived neurons obtained from Friedreich ataxia (FRDA) patients and healthy subjects, FRDA neurons and CT neurons, respectively, to unveil phenotypic alterations related to frataxin (FXN) deficiency an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90bcf3dca8739501581f2ba868e9ea74
https://pubmed.ncbi.nlm.nih.gov/28175303
https://pubmed.ncbi.nlm.nih.gov/28175303
Autor:
Franca Codazzi, Stefano F. Cappa, Stefano Olivieri, Mariasabina Pesca, Ilaria Pelizzoni, Diego Franciotta, Antonio Conti, Carlo Vittorio Cannistraci, Alessandro Campanella, Giuseppe Magnani, Sandro Iannaccone, Massimo Alessio, Marco Barbariga
Publikováno v:
The Journal of Neuroscience. 31:18568-18577
Parkinson's disease is a neurodegenerative disorder characterized by oxidative stress and CNS iron deposition. Ceruloplasmin is an extracellular ferroxidase that regulates cellular iron loading and export, and hence protects tissues from oxidative da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7475968e5089834f0750b07e7d1c5ec7
https://doi.org/10.1523/jneurosci.3768-11.2011
https://doi.org/10.1523/jneurosci.3768-11.2011
Publikováno v:
Journal of Neurochemistry. 120:269-278
The divalent metal transporter 1 (DMT1) is the best characterized Fe²⁺ transporter involved in cellular iron uptake in mammals. Four possible isoforms have been identified as a result of alternative promoter (DMT1-1A and DMT1-1B) and alternative s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f98bf387eebc6fca6ac4ad0c427cee1b
https://doi.org/10.1111/j.1471-4159.2011.07578.x
https://doi.org/10.1111/j.1471-4159.2011.07578.x
Autor:
Marco Francesco Morini, Daniele Zacchetti, Romina Macco, Franca Codazzi, Ilaria Pelizzoni, Fabio Grohovaz
Publikováno v:
Aging Cell. 10:172-183
The characterization of iron handling in neurons is still lacking, with contradictory and incomplete results. In particular, the relevance of non-transferrin-bound iron (NTBI), under physiologic conditions, during aging and in neurodegenerative disor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92b8080f78decc3ba85816ad26906133
https://doi.org/10.1111/j.1474-9726.2010.00652.x
https://doi.org/10.1111/j.1474-9726.2010.00652.x
Autor:
Romina Macco, Alessandra Consonni, Marija Mihailovich, Daniele Zacchetti, Ilaria Pelizzoni, Barbara Bettegazzi, Alessandra Di Cesare, Franca Codazzi, Fabio Grohovaz
Publikováno v:
European Journal of Neuroscience. 33:236-243
BACE1 and BACE2 are two closely related membrane-bound aspartic proteases. BACE1 is widely recognized as the neuronal β-secretase that cleaves the amyloid-β precursor protein, thus allowing the production of amyloid-β, i.e. the peptide that has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0d9b3ec90b871fef58f5d16a68e36a6
https://doi.org/10.1111/j.1460-9568.2010.07482.x
https://doi.org/10.1111/j.1460-9568.2010.07482.x
Publikováno v:
Biochemical Society Transactions. 36:1309-1312
Iron and calcium are required for general cellular functions, as well as for specific neuronal-related activities. However, a pathological increase in their levels favours oxidative stress and mitochondrial damage, leading to neuronal death. Neurodeg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f4bcb26dcf587d9fc70d46fc84e0c0e
https://doi.org/10.1042/bst0361309
https://doi.org/10.1042/bst0361309
Autor:
Ilaria, Pelizzoni, Romina, Macco, Marco Francesco, Morini, Daniele, Zacchetti, Fabio, Grohovaz, Franca, Codazzi
Publikováno v:
Aging cell. 10(1)
The characterization of iron handling in neurons is still lacking, with contradictory and incomplete results. In particular, the relevance of non-transferrin-bound iron (NTBI), under physiologic conditions, during aging and in neurodegenerative disor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0f50fcc466ad2a18a230c38b09162e88
https://pubmed.ncbi.nlm.nih.gov/21108725
https://pubmed.ncbi.nlm.nih.gov/21108725
Autor:
Barbara, Bettegazzi, Marija, Mihailovich, Alessandra, Di Cesare, Alessandra, Consonni, Romina, Macco, Ilaria, Pelizzoni, Franca, Codazzi, Fabio, Grohovaz, Daniele, Zacchetti
Publikováno v:
The European journal of neuroscience. 33(2)
BACE1 and BACE2 are two closely related membrane-bound aspartic proteases. BACE1 is widely recognized as the neuronal β-secretase that cleaves the amyloid-β precursor protein, thus allowing the production of amyloid-β, i.e. the peptide that has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5390c7fe5c35f9dbe166aa090fbf4793
https://pubmed.ncbi.nlm.nih.gov/21073551
https://pubmed.ncbi.nlm.nih.gov/21073551