Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Ilaria, Morella"'
Autor:
Francesca Giammello, Chiara Biella, Erica Cecilia Priori, Matilde Amat Di San Filippo, Roberta Leone, Francesca D’Ambrosio, Martina Paterno’, Giulia Cassioli, Antea Minetti, Francesca Macchi, Cristina Spalletti, Ilaria Morella, Cristina Ruberti, Beatrice Tremonti, Federica Barbieri, Giuseppe Lombardi, Riccardo Brambilla, Tullio Florio, Rossella Galli, Paola Rossi, Federico Brandalise
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-28 (2024)
Abstract Background Glioblastoma (GBM) stands as the most prevalent and aggressive form of adult gliomas. Despite the implementation of intensive therapeutic approaches involving surgery, radiation, and chemotherapy, Glioblastoma Stem Cells contribut
Externí odkaz:
https://doaj.org/article/f620b5142f8b4c7d9c81860a86cd23a7
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Externí odkaz:
https://doaj.org/article/6328d3f4fda440029d0628d0d205a4d2
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Neurodevelopmental disorders (NDDs) include a broad spectrum of pathological conditions that affect >4% of children worldwide, share common features and present a variegated genetic origin. They include clinically defined diseases, such as autism spe
Externí odkaz:
https://doaj.org/article/8629bf3dd9634fffb4c3993a57b0fdc2
Autor:
Perrine F. Kretz, Christel Wagner, Anna Mikhaleva, Charlotte Montillot, Sylvain Hugel, Ilaria Morella, Meghna Kannan, Marie-Christine Fischer, Maxence Milhau, Ipek Yalcin, Riccardo Brambilla, Mohammed Selloum, Yann Herault, Alexandre Reymond, Stephan C. Collins, Binnaz Yalcin
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-22 (2023)
Abstract Background Using mouse genetic studies and systematic assessments of brain neuroanatomical phenotypes, we set out to identify which of the 30 genes causes brain defects at the autism-associated 16p11.2 locus. Results We show that multiple ge
Externí odkaz:
https://doaj.org/article/37637093eaea40888cb9b6562d451f96
Autor:
Marzia Indrigo, Ilaria Morella, Daniel Orellana, Raffaele d'Isa, Alessandro Papale, Riccardo Parra, Antonia Gurgone, Daniela Lecca, Anna Cavaccini, Cezar M Tigaret, Alfredo Cagnotto, Kimberley Jones, Simon Brooks, Gian Michele Ratto, Nicholas D Allen, Mariah J Lelos, Silvia Middei, Maurizio Giustetto, Anna R Carta, Raffaella Tonini, Mario Salmona, Jeremy Hall, Kerrie Thomas, Riccardo Brambilla, Stefania Fasano
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 11, Pp 1-25 (2023)
Abstract Cell signaling is central to neuronal activity and its dysregulation may lead to neurodegeneration and cognitive decline. Here, we show that selective genetic potentiation of neuronal ERK signaling prevents cell death in vitro and in vivo in
Externí odkaz:
https://doaj.org/article/07ec956f4df240a18ad3746f40460254
Autor:
Ilaria Morella, Veronika Pohořalá, Claudia Calpe-López, Riccardo Brambilla, Rainer Spanagel, Rick E. Bernardi
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Ras/Raf/MEK/ERK (Ras-ERK) signaling has been demonstrated to play a role in the effects of drugs of abuse such as cocaine and alcohol, but has not been extensively examined in nicotine-related reward behaviors. We examined the role of Ras Guanine Nuc
Externí odkaz:
https://doaj.org/article/d93da21c946344f8a01c539c7f403ada
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
In the striatum, the input nucleus of the basal ganglia, the extracellular-signal-regulated kinase (ERK) pathway, necessary for various forms of behavioral plasticity, is triggered by the combined engagement of dopamine D1 and ionotropic glutamate re
Externí odkaz:
https://doaj.org/article/e15ce3af1d96469988cddd18ed3cadc4
Autor:
Gerard W. O'Keeffe, Nurulain T. Zaveri, Ilaria Morella, Daniela Mercatelli, Martina Mazzocchi, Riccardo Brambilla, Michele Morari, Alberto Brugnoli, Stefania Fasano, Richard R. Neubig, Clarissa Anna Pisanò
Background and purpose Regulator of G-protein signal 4 (RGS4) is a signal transduction protein that accelerates intrinsic GTPase activity of Gαi/o and Gαq subunits, suppressing GPCR signaling. Here we investigate whether RGS4 modulates nociceptin/o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a564af83ffb46926abc647c19aea84b
https://hdl.handle.net/11392/2472868
https://hdl.handle.net/11392/2472868
Autor:
Massimo Trusel, Anna Cavaccini, Marta Gritti, Barbara Greco, Pierre-Philippe Saintot, Cristiano Nazzaro, Milica Cerovic, Ilaria Morella, Riccardo Brambilla, Raffaella Tonini
Publikováno v:
Cell Reports, Vol 13, Iss 7, Pp 1353-1365 (2015)
The basal ganglia play a critical role in shaping motor behavior. For this function, the activity of medium spiny neurons (MSNs) of the striatonigral and striatopallidal pathways must be integrated. It remains unclear whether the activity of the two
Externí odkaz:
https://doaj.org/article/17b73b6ef9de4c12b544f869027b9565
Autor:
Perrine F. Kretz, Christel Wagner, Charlotte Montillot, Sylvain Hugel, Ilaria Morella, Meghna Kannan, Anna Mikhaleva, Marie-Christine Fischer, Maxence Milhau, Riccardo Brambilla, Yann Herault, Alexandre Reymond, Mohammed Selloum, Stephan C. Collins, Binnaz Yalcin
Using mouse genetic studies, we set out to identify which of the 30 genes causes brain size and other NeuroAnatomical Phenotypes (NAPs) at the autism-associated 16p11.2 locus. We show that multiple genes mapping to this region interact to regulate br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::962d0697a37ccc6705b1642f19fb8c36
https://doi.org/10.1101/2022.01.23.477432
https://doi.org/10.1101/2022.01.23.477432