Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Ilaria, Genovese"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Mitochondria are physically associated with other organelles, such as ER and lysosomes, forming a complex network that is crucial for cell homeostasis regulation. Inter-organelle relationships are finely regulated by both tether systems, which mainta
Externí odkaz:
https://doaj.org/article/edbffe06a7df447c9b1fad047c722639
Publikováno v:
EBioMedicine, Vol 59, Iss , Pp 102943- (2020)
Mitochondria are dynamic organelles that have essential metabolic activity and are regarded as signalling hubs with biosynthetic, bioenergetics and signalling functions that orchestrate key biological pathways. However, mitochondria can influence all
Externí odkaz:
https://doaj.org/article/56dc59a669984f21b7a3eeb0561d1541
Autor:
Claudia, Tito, Ilaria, Genovese, Flavia, Giamogante, Anna, Benedetti, Selenia, Miglietta, Lucia, Barazzuol, Loredana, Cristiano, Alessia, Iaiza, Sabatino, Carolini, Luciana De Angelis, Silvia, Masciarelli, Stefania Annarita Nottola, Giuseppe, Familiari, Vincenzo, Petrozza, Mattia, Lauriola, Tamagnone, Luca, Andrea, Ilari, Tito, Calì, Hector, H Valdivia, Carmen, R Valdivia, Gianni, Colotti, Francesco, Fazi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2601::1f5c95a5955c98b87171767cf9470bdd
https://hdl.handle.net/10807/244014
https://hdl.handle.net/10807/244014
Autor:
Lorenzo Turcano, Esther Torrente, Antonino Missineo, Matteo Andreini, Marina Gramiccia, Trentina Di Muccio, Ilaria Genovese, Annarita Fiorillo, Steven Harper, Alberto Bresciani, Gianni Colotti, Andrea Ilari
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 11, p e0006969 (2018)
Trypanothione reductase (TR) is considered to be one of the best targets to find new drugs against Leishmaniasis. This enzyme is fundamental for parasite survival in the host since it reduces trypanothione, a molecule used by the tryparedoxin/trypare
Externí odkaz:
https://doaj.org/article/af5f06d4d9594ea4b914709906958f7d
Autor:
Claudia Tito, Ilaria Genovese, Flavia Giamogante, Anna Benedetti, Selenia Miglietta, Lucia Barazzuol, Loredana Cristiano, Sabatino Carolini, Luciana De Angelis, Silvia Masciarelli, Stefania Annarita Nottola, Giuseppe Familiari, Vincenzo Petrozza, Mattia Lauriola, Luca Tamagnone, Andrea Ilari, Tito Calì, Gianni Colotti, Francesco FAZI
The epidermal growth factor receptor (EGFR) is one of the main tumor drivers, and is an important therapeutic target for many cancers. Calcium is important in EGFR internalization and in EGFR signaling pathways. Sorcin is one of the most important ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::354661cf7a30602bea167e2718c5fa29
https://doi.org/10.21203/rs.3.rs-2252273/v1
https://doi.org/10.21203/rs.3.rs-2252273/v1
Autor:
Gianni Colotti, Elena Poser, Annarita Fiorillo, Ilaria Genovese, Valerio Chiarini, Andrea Ilari
Publikováno v:
Molecules, Vol 19, Iss 9, Pp 13976-13989 (2014)
Sorcin is a penta-EF hand calcium binding protein, which participates in the regulation of calcium homeostasis in cells. Sorcin regulates calcium channels and exchangers located at the plasma membrane and at the endo/sarcoplasmic reticulum (ER/SR), a
Externí odkaz:
https://doaj.org/article/fd489642144849a792d604d48d07f37d
Autor:
Luciana Mosca, Elisabetta Falvo, Pierpaolo Ceci, Elena Poser, Ilaria Genovese, Giulia Guarguaglini, Gianni Colotti
Publikováno v:
Applied Sciences, Vol 7, Iss 1, p 101 (2017)
The ability of ferritin to bind and deliver metals and metal-based drugs to human neuroblastoma SH-SY5Y cells was studied. We used heavy chain (H) ferritin-based metal-containing nanocarriers to test whether these constructs, which are able to cross
Externí odkaz:
https://doaj.org/article/c73df262e3564987a80a026e246636c5
Autor:
Ilaria Genovese, Lorenzo Modesti, Gianluca Aguiari, Paolo Pinton, Marianna Carinci, Carlotta Giorgi
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 4770, p 4770 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 4770, p 4770 (2021)
Mitochondria are key regulators of cell survival and are involved in a plethora of mechanisms, such as metabolism, Ca2+ signaling, reactive oxygen species (ROS) production, mitophagy and mitochondrial transfer, fusion, and fission (known as mitochond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::291af68ca967f7e6b7f70b4a4d3e748f
https://pubmed.ncbi.nlm.nih.gov/33946271
https://pubmed.ncbi.nlm.nih.gov/33946271
Autor:
Paolo Pinton, Alberto Danese, Bianca Vezzani, Stefano Pelucchi, Carlotta Giorgi, Lorenzo Modesti, Veronica Angela Maria Vitto, Virginia Corazzi, Ilaria Genovese
Publikováno v:
Cell calcium. 92
As pivotal players in cellular metabolism, mitochondria have a double-faceted role in the final decision of cell fate. This is true for all cell types, but it is even more important and intriguing in the cancer setting. Mitochondria regulate cell fat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05997364ad2d6d921d7e121720fd814d
https://pubmed.ncbi.nlm.nih.gov/33096320
https://pubmed.ncbi.nlm.nih.gov/33096320
Autor:
Mariasole, Perrone, Natascia, Caroccia, Ilaria, Genovese, Sonia, Missiroli, Lorenzo, Modesti, Gaia, Pedriali, Bianca, Vezzani, Veronica Angela Maria, Vitto, Michele, Antenori, Magdalena, Lebiedzinska-Arciszewska, Mariusz R, Wieckowski, Carlotta, Giorgi, Paolo, Pinton
Publikováno v:
International review of cell and molecular biology. 350
Mitochondria and endoplasmic reticulum (ER) are fundamental in the control of cell physiology regulating several signal transduction pathways. They continuously communicate exchanging messages in their contact sites called MAMs (mitochondria-associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d26963bd1c16a011d2ab7f14fa33cec8
https://pubmed.ncbi.nlm.nih.gov/32138899
https://pubmed.ncbi.nlm.nih.gov/32138899