Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Ilaria, Dettori"'
Autor:
Martina Venturini, Federica Cherchi, Clara Santalmasi, Lucia Frulloni, Ilaria Dettori, Daniela Catarzi, Felicita Pedata, Vittoria Colotta, Flavia Varano, Elisabetta Coppi, Anna Maria Pugliese
Publikováno v:
Biomolecules, Vol 13, Iss 6, p 894 (2023)
In recent years, the use of multi-target compounds has become an increasingly pursued strategy to treat complex pathologies, including cerebral ischemia. Adenosine and its receptors (A1AR, A2AAR, A2BAR, A3AR) are known to play a crucial role in synap
Externí odkaz:
https://doaj.org/article/967ca781ef344086a54e640f6929530b
Autor:
Ilaria Dettori, Irene Fusco, Irene Bulli, Lisa Gaviano, Elisabetta Coppi, Federica Cherchi, Martina Venturini, Lorenzo Di Cesare Mannelli, Carla Ghelardini, Alessio Nocentini, Claudiu T. Supuran, Anna Maria Pugliese, Felicita Pedata
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 964-976 (2021)
Ischaemic stroke is a leading cause of death and disability. One of the major pathogenic mechanisms after ischaemia includes the switch to the glycolytic pathway, leading to tissue acidification. Carbonic anhydrase (CA) contributes to pH regulation.
Externí odkaz:
https://doaj.org/article/b71f43961f06497bbcb2ac3275cfbddc
Autor:
Ilaria Dettori, Lisa Gaviano, Filippo Ugolini, Daniele Lana, Irene Bulli, Giada Magni, Francesca Rossi, Maria Grazia Giovannini, Felicita Pedata
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
Cerebral ischemia is a multifactorial pathology characterized first by an acute injury, due to excitotoxicity, followed by a secondary brain injury that develops hours to days after ischemia. During ischemia, adenosine acts as an endogenous neuroprot
Externí odkaz:
https://doaj.org/article/322b25e979994da1b703b91879125f57
Autor:
Elisabetta Coppi, Ilaria Dettori, Federica Cherchi, Irene Bulli, Martina Venturini, Felicita Pedata, Anna Maria Pugliese
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
Externí odkaz:
https://doaj.org/article/f3f490cc7d57484caa430f15f3daf60a
Autor:
Xavier Guitart, Jordi Bonaventura, William Rea, Marco Orrú, Lucrezia Cellai, Ilaria Dettori, Felicita Pedata, Marc Brugarolas, Antonio Cortés, Vicent Casadó, Ching-Pang Chang, Manikandan Narayanan, Yijuang Chern, Sergi Ferré
Publikováno v:
Neurobiology of Disease, Vol 96, Iss , Pp 47-53 (2016)
The initial goal of this study was to investigate alterations in adenosine A2A receptor (A2AR) density or function in a rat model of Huntington disease (HD) with reported insensitivity to an A2AR antagonist. Unsuspected negative results led to the hy
Externí odkaz:
https://doaj.org/article/5f0fc91ff1fc465fa5369d2dd9737a1f
Autor:
Ilaria Dettori, Lisa Gaviano, Alessia Melani, Laura Lucarini, Mariaconcetta Durante, Emanuela Masini, Felicita Pedata
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Cerebral ischemia is a multifactorial pathology characterized by different events evolving in time. The acute injury, characterized by excitoxicity, is followed by a secondary brain injury that develops from hours to days after ischemia. Extracellula
Externí odkaz:
https://doaj.org/article/461c10c2b8e247d4b851c1af7f8fa7df
Autor:
Irene Fusco, Filippo Ugolini, Daniele Lana, Elisabetta Coppi, Ilaria Dettori, Lisa Gaviano, Daniele Nosi, Federica Cherchi, Felicita Pedata, Maria G. Giovannini, Anna M. Pugliese
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Ischemia is a multifactorial pathology characterized by different events evolving in time. Immediately after the ischemic insult, primary brain damage is due to the massive increase of extracellular glutamate. Adenosine in the brain increases dramati
Externí odkaz:
https://doaj.org/article/c7baccce2d2d49ddae369f4769f945e0
Autor:
Irene Fusco, Martina Venturini, Felicita Pedata, Lorenzo Di Cesare Mannelli, Lisa Gaviano, Anna Maria Pugliese, Claudiu T. Supuran, Irene Bulli, Federica Cherchi, Carla Ghelardini, Ilaria Dettori, Alessio Nocentini, Elisabetta Coppi
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 964-976 (2021)
Ischaemic stroke is a leading cause of death and disability. One of the major pathogenic mechanisms after ischaemia includes the switch to the glycolytic pathway, leading to tissue acidification. Carbonic anhydrase (CA) contributes to pH regulation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b16c961b3e115d43cb24aab3d9c6e84
https://doaj.org/article/b71f43961f06497bbcb2ac3275cfbddc
https://doaj.org/article/b71f43961f06497bbcb2ac3275cfbddc
Autor:
Maria Grazia Giovannini, Giada Magni, Felicita Pedata, Francesca Rossi, Daniele Lana, Filippo Ugolini, Irene Bulli, Ilaria Dettori, Lisa Gaviano
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
Neuropharmacology (2020).
info:cnr-pdr/source/autori:Ilaria Dettori; Lisa Gaviano; Filippo Ugolini; Daniele Lana; Irene Bulli; Giada Magni; Francesca Rossi; Maria Grazia Giovannini; Felicita Pedata/titolo:Protective effect of adenosine A2B receptor agonist, BAY60-6583, against transient focal brain ischemia in rat/doi:/rivista:Neuropharmacology/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume
Neuropharmacology (2020).
info:cnr-pdr/source/autori:Ilaria Dettori; Lisa Gaviano; Filippo Ugolini; Daniele Lana; Irene Bulli; Giada Magni; Francesca Rossi; Maria Grazia Giovannini; Felicita Pedata/titolo:Protective effect of adenosine A2B receptor agonist, BAY60-6583, against transient focal brain ischemia in rat/doi:/rivista:Neuropharmacology/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume
Cerebral ischemia is a multifactorial pathology characterized first by an acute injury, due to excitotoxicity, followed by a secondary brain injury that develops hours to days after ischemia. During ischemia, adenosine acts as an endogenous neuroprot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efd23bb902e9c8a107bfb43405470dfd
https://doi.org/10.3389/fphar.2020.588757
https://doi.org/10.3389/fphar.2020.588757