Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Ilana Talior"'
Publikováno v:
Regenerative Engineering and Translational Medicine. 9:4-21
The subcutaneous space has been shown to be a suitable site for islet transplantation, however an abundance of islets is required to achieve normoglycemia, often requiring multiple donors. The loss of islets is due to the hypoxic conditions islets ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6d99e87d75d0090bec79cef7ca19377
https://doi.org/10.1101/2020.06.26.172148
https://doi.org/10.1101/2020.06.26.172148
Publikováno v:
Biomaterials. 144:199-210
The IGF-1 signaling pathway and IGF-1-dependent macrophage/endothelial cell crosstalk was found to be critical features of the vascular regenerative effect displayed by implanted methacrylic acid –co-isodecyl acrylate (MAA-co-IDA; 40% MAA) coated d
Autor:
Michael V. Sefton, Alexandra Lisovsky, Andrew Emili, Hongbo Guo, Ilana Talior-Volodarsky, Michael Dean Chamberlain, Redouan Mahou, Laura A. Wells, Ruth Isserlin
Publikováno v:
Proceedings of the National Academy of Sciences. 112:10673-10678
An unbiased phosphoproteomic method was used to identify biomaterial-associated changes in the phosphorylation patterns of macrophage-like cells. The phosphorylation differences between differentiated THP1 (dTHP1) cells treated for 10, 20, or 30 min
Autor:
Cédric Zeltz, Donald Gullberg, Kim A. Connelly, Christopher A. McCulloch, Pamma D. Arora, Ilana Talior-Volodarsky, Yongqiang Wang
Publikováno v:
Journal of Cellular Physiology. 230:327-336
The adhesion of cardiac fibroblasts to the glycated collagen interstitium in diabetics is associated with de novo expression of the α11 integrin, myofibroblast formation and cardiac fibrosis. We examined how methylglyoxal-glycated collagen regulates
Autor:
Christopher A. McCulloch, Dennis G. Cvitkovitch, Mwayi P. Kazembe, Anil Kishen, Vanessa I. Pinto, Ilana Talior, Suja Shrestha, Calvin D. Torneck, Anousheh Persadmehr
Publikováno v:
Journal of Endodontics. 40:703-709
Collagen is the major structural protein of human dentin. Degradation of collagen by bacterial enzymes can facilitate microbial penetration, compromise structural/interfacial integrity, and lower resistance to fracture of dentin. We evaluated the abi
Autor:
Ilana Talior-Volodarsky, Donald Gullberg, Christopher A. McCulloch, Pamma D. Arora, Kim A. Connelly
Publikováno v:
Cardiovascular Research. 96:265-275
Aims Diabetic cardiomyopathy is characterized by the production of a disorganized fibrotic matrix in the absence of coronary atherosclerosis and hypertension. We examined whether adhesion of cardiac fibroblasts to glycated collagens mediates the diff
Autor:
Christopher A. McCulloch, Ilana Talior-Volodarsky, Carol Laschinger, Dhaarmini Rajshankar, Gregory P. Downey, Yongqiang Wang, Qin Wang
Publikováno v:
Journal of Biological Chemistry. 285:22308-22317
Interleukin-1 (IL-1) induces extracellular matrix degradation as a result of increased expression of matrix metalloproteinases (MMPs). We examined adhesion-restricted signaling pathways that enable IL-1-induced MMP release in human gingival and murin
Autor:
Craig A. Simmons, Matthew W. C. Chan, Edmond W. K. Young, Wilson Lee, Carol Laschinger, Konesh Sivagurunathan, Juliana Birek, Amy Yuen, Ilana Talior, Christopher A. McCulloch, Emily Won
Publikováno v:
Matrix Biology. 29:537-548
Fibrosis is a frequent complication of diabetes mellitus in many organs and tissues but the mechanism of how diabetes-induced glycation of extracellular matrix proteins impacts the formation of fibrotic lesions is not defined. As fibrosis is mediated
Autor:
Varinder K. Randhawa, John H. Hartwig, Nish Patel, Shuhei Ishikura, Amira Klip, Ilana Talior-Volodarsky, Alex Won-Pang Cheng
Publikováno v:
Journal of Biological Chemistry. 283:27208-27219
Insulin increases glucose uptake into muscle by enhancing the surface recycling of GLUT4 transporters. In myoblasts, insulin signals bifurcate downstream of phosphatidylinositol 3-kinase into separate Akt and Rac/actin arms. Akt-mediated Rab-GAP AS16