Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Ilana R. Bernstein"'
Autor:
Jacinta H. Martin, Ilana R. Bernstein, Jess M. Lyons, Ariel R. Brady, Nishani S. Mabotuwana, Simone J. Stanger, Camila Salum De Oliveira, Katerina B. Damyanova, Brett Nixon, Tessa Lord
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Oxygen availability can have profound effects on cell fate decisions and survival, in part by regulating expression of hypoxia-inducible factors (HIFs). In the ovary, HIF expression has been characterised in granulosa cells, however, any req
Externí odkaz:
https://doaj.org/article/5dda65dc8bf448c0add10432000f1a06
Autor:
Ilana R. Bernstein, Brett Nixon, Jess M. Lyons, Katerina B. Damyanova, Camila S. De Oliveira, Nishani S. Mabotuwana, Simone J. Stanger, Gerard E. Kaiko, Tan Hui Ying, Jon M. Oatley, Nicole M. Skillen, Alyssa J. Lochrin, Jera L. Peters, Tessa Lord
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108424- (2023)
Summary: In this study we explored the role of hypoxia and the hypoxia-inducible transcription factor EPAS1 in regulating spermatogonial stem cell (SSC) function in the mouse testis. We have demonstrated that SSCs reside in hypoxic microenvironments
Externí odkaz:
https://doaj.org/article/2fa4f90c3ac04a43b6a08638c06119ad
Autor:
David A. Skerrett-Byrne, Brett Nixon, Elizabeth G. Bromfield, James Breen, Natalie A. Trigg, Simone J. Stanger, Ilana R. Bernstein, Amanda L. Anderson, Tessa Lord, R. John Aitken, Shaun D. Roman, Sarah A. Robertson, John E. Schjenken
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-22 (2021)
Abstract Background The seminal vesicles synthesise bioactive factors that support gamete function, modulate the female reproductive tract to promote implantation, and influence developmental programming of offspring phenotype. Despite the significan
Externí odkaz:
https://doaj.org/article/627867058628482e8338e8767450f0aa
Autor:
Wei Zhou, Simone J. Stanger, Amanda L. Anderson, Ilana R. Bernstein, Geoffry N. De Iuliis, Adam McCluskey, Eileen A. McLaughlin, Matthew D. Dun, Brett Nixon
Publikováno v:
BMC Biology, Vol 17, Iss 1, Pp 1-18 (2019)
Abstract Background The mammalian epididymis is responsible for the provision of a highly specialized environment in which spermatozoa acquire functional maturity and are subsequently stored in preparation for ejaculation. Making important contributi
Externí odkaz:
https://doaj.org/article/d95613235ed745e3ab866db445daf2ea
Autor:
Brett Nixon, Ilana R. Bernstein, Shenae L. Cafe, Maryse Delehedde, Nicolas Sergeant, Amanda L. Anderson, Natalie A. Trigg, Andrew L. Eamens, Tessa Lord, Matthew D. Dun, Geoffry N. De Iuliis, Elizabeth G. Bromfield
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Oxidative stress is a leading causative agent in the defective sperm function associated with male infertility. Such stress commonly manifests via the accumulation of pathological levels of the electrophilic aldehyde, 4-hydroxynonenal (4HNE), generat
Externí odkaz:
https://doaj.org/article/7ecc4bb88d25498fa20ae3cf1122467c
Autor:
Jessie M. Sutherland, Alexander P. Sobinoff, Kara M. Gunter, Barbara A. Fraser, Victoria Pye, Ilana R. Bernstein, Evan Boon, Nicole A. Siddall, Luisa I. De Andres, Gary R. Hime, Janet E. Holt, Thomas Graf, Eileen A. McLaughlin
Publikováno v:
Biomolecules, Vol 5, Iss 3, Pp 1228-1244 (2015)
Characterizing the mechanisms underlying follicle development in the ovary is crucial to understanding female fertility and is an area of increasing research interest. The RNA binding protein Musashi is essential for post-transcriptional regulation o
Externí odkaz:
https://doaj.org/article/b97c9382eb2a417a95eb6f605683a472
Autor:
Eileen A. McLaughlin, Jessie M. Sutherland, Bettina P. Mihalas, Brett Nixon, Ilana R. Bernstein, Mark J. Robertson, Kate A. Redgrove, Adam McCluskey, Janet E. Holt
Publikováno v:
The FASEB Journal. 34:5162-5177
During folliculogenesis, oocytes are dependent on metabolic and molecular support from surrounding somatic cells. Here, we examined the role of the dynamin (DNM) family of mechanoenzymes in mediating endocytotic uptake into growing follicular oocytes
Autor:
Brett Nixon, John E. Schjenken, Natalie A. Trigg, James Breen, Tessa Lord, R. John Aitken, Simone J. Stanger, Elizabeth G. Bromfield, Sarah A. Robertson, Ilana R. Bernstein, David A. Skerrett-Byrne, Shaun D. Roman, Amanda L. Anderson
Publikováno v:
BMC Genomics
BMC Genomics, Vol 22, Iss 1, Pp 1-22 (2021)
BMC Genomics, Vol 22, Iss 1, Pp 1-22 (2021)
Background The seminal vesicles synthesise bioactive factors that support gamete function, modulate the female reproductive tract to promote implantation, and influence developmental programming of offspring phenotype. Despite the significance of the
Autor:
David A. Skerrett-Byrne, Amanda L. Anderson, Elizabeth G. Bromfield, Ilana R. Bernstein, Jess E. Mulhall, John E. Schjenken, Matthew D. Dun, Sean J. Humphrey, Brett Nixon
Publikováno v:
Cell Reports. 41:111655
Spermatozoa acquire fertilization potential during passage through a highly specialized region of the extratesticular ductal system known as the epididymis. In the absence of de novo gene transcription or protein translation, this functional transfor
Autor:
Amanda L. Anderson, Wei Zhou, Eileen A. McLaughlin, Brett Nixon, Simone J. Stanger, Matthew D. Dun, Adam McCluskey, Geoffry N. De Iuliis, Ilana R. Bernstein
Publikováno v:
BMC Biology, Vol 17, Iss 1, Pp 1-18 (2019)
BMC Biology
BMC Biology
Background The mammalian epididymis is responsible for the provision of a highly specialized environment in which spermatozoa acquire functional maturity and are subsequently stored in preparation for ejaculation. Making important contributions to bo