Zobrazeno 1 - 10
of 229
pro vyhledávání: '"Ilan Davis"'
Publikováno v:
Fly, Vol 18, Iss 1 (2024)
In situ hybridization techniques are powerful methods for exploring gene expression in a wide range of biological contexts, providing spatial information that is most often lost in traditional biochemical techniques. However, many in situ hybridizati
Externí odkaz:
https://doaj.org/article/8f2c4ac7d60c4047acea104f06a45eab
Autor:
Qi Hu, Martin Hailstone, Jingyu Wang, Matthew Wincott, Danail Stoychev, Huriye Atilgan, Dalia Gala, Tai Chaiamarit, Richard M. Parton, Jacopo Antonello, Adam M. Packer, Ilan Davis, Martin J. Booth
Publikováno v:
Light: Science & Applications, Vol 12, Iss 1, Pp 1-13 (2023)
Abstract The resolution and contrast of microscope imaging is often affected by aberrations introduced by imperfect optical systems and inhomogeneous refractive structures in specimens. Adaptive optics (AO) compensates these aberrations and restores
Externí odkaz:
https://doaj.org/article/72f31cbe374c4c5497ef18ac9fba1bf8
Autor:
Andrew Jefferson, Matthew Wincott, Martin J. Booth, Ian M. Dobbie, Richard M. Parton, Ilan Davis
Publikováno v:
Wellcome Open Research, Vol 6 (2022)
Commercial fluorescence microscope stands and fully automated XYZt fluorescence imaging systems are generally beyond the limited budgets available for teaching and outreach. We have addressed this problem by developing “Microscopi”, an accessible
Externí odkaz:
https://doaj.org/article/b8b9858f54d04096a77cd4b209a736f3
Autor:
Ian M. Dobbie, Mick A. Phillips, Ilan Davis, Nicholas Hall, David Miguel Susano Pinto, Richard M. Parton, Julio Mateos-Langerak, Danail V. Stoychev, Josh Titlow, Tiago Susano Pinto, Thomas Parks, Martin J. Booth, John W. Sedat
Publikováno v:
Wellcome Open Research, Vol 6 (2022)
We have developed “Microscope-Cockpit” (Cockpit), a highly adaptable open source user-friendly Python-based Graphical User Interface (GUI) environment for precision control of both simple and elaborate bespoke microscope systems. The user environ
Externí odkaz:
https://doaj.org/article/1587fdc0d1a6481ba0dd87bd1e181e34
Autor:
Jeffrey Y Lee, Peter AC Wing, Dalia S Gala, Marko Noerenberg, Aino I Järvelin, Joshua Titlow, Xiaodong Zhuang, Natasha Palmalux, Louisa Iselin, Mary Kay Thompson, Richard M Parton, Maria Prange-Barczynska, Alan Wainman, Francisco J Salguero, Tammie Bishop, Daniel Agranoff, William James, Alfredo Castello, Jane A McKeating, Ilan Davis
Publikováno v:
eLife, Vol 11 (2022)
Despite an unprecedented global research effort on SARS-CoV-2, early replication events remain poorly understood. Given the clinical importance of emergent viral variants with increased transmission, there is an urgent need to understand the early st
Externí odkaz:
https://doaj.org/article/9faa31e3a35e4bed8c3ceedffa1e3c5f
Hypoxic and pharmacological activation of HIF inhibits SARS-CoV-2 infection of lung epithelial cells
Autor:
Peter A.C. Wing, Thomas P. Keeley, Xiaodong Zhuang, Jeffrey Y. Lee, Maria Prange-Barczynska, Senko Tsukuda, Sophie B. Morgan, Adam C. Harding, Isobel L.A. Argles, Samvid Kurlekar, Marko Noerenberg, Craig P. Thompson, Kuan-Ying A. Huang, Peter Balfe, Koichi Watashi, Alfredo Castello, Timothy S.C. Hinks, William James, Peter J. Ratcliffe, Ilan Davis, Emma J. Hodson, Tammie Bishop, Jane A. McKeating
Publikováno v:
Cell Reports, Vol 35, Iss 3, Pp 109020- (2021)
Summary: COVID-19, caused by the novel coronavirus SARS-CoV-2, is a global health issue with more than 2 million fatalities to date. Viral replication is shaped by the cellular microenvironment, and one important factor to consider is oxygen tension,
Externí odkaz:
https://doaj.org/article/0e81e8390d8b4bff8a888f023b7b0038
Autor:
Matthew Wincott, Andrew Jefferson, Ian M. Dobbie, Martin J. Booth, Ilan Davis, Richard M. Parton
Publikováno v:
Wellcome Open Research, Vol 6 (2021)
Commercial fluorescence microscope stands and fully automated XYZt fluorescence imaging systems are generally beyond the limited budgets available for teaching and outreach. We have addressed this problem by developing “Microscopi”, an accessible
Externí odkaz:
https://doaj.org/article/36e75b3ba6e0492f8b4d5820bc2a05c8
Autor:
Jessica Mitchell, Carlas S Smith, Josh Titlow, Nils Otto, Pieter van Velde, Martin Booth, Ilan Davis, Scott Waddell
Publikováno v:
eLife, Vol 10 (2021)
Memory-relevant neuronal plasticity is believed to require local translation of new proteins at synapses. Understanding this process requires the visualization of the relevant mRNAs within these neuronal compartments. Here, we used single-molecule fl
Externí odkaz:
https://doaj.org/article/3f446909952b4207a1bdaa5913bef53f
Publikováno v:
Open Biology, Vol 10, Iss 12 (2020)
The human immunodeficiency virus type 1 (HIV-1) proteome is expressed from alternatively spliced and unspliced genomic RNAs. However, HIV-1 RNAs that are not fully spliced are perceived by the host machinery as defective and are retained in the nucle
Externí odkaz:
https://doaj.org/article/7f261dfb83514a8483bca361a7bfc5e2
Autor:
Tamsin J. Samuels, Yoav Arava, Aino I. Järvelin, Francesca Robertson, Jeffrey Y. Lee, Lu Yang, Ching-Po Yang, Tzumin Lee, David Ish-Horowicz, Ilan Davis
Publikováno v:
Biology Open, Vol 9, Iss 5 (2020)
During Drosophila and vertebrate brain development, the conserved transcription factor Prospero/Prox1 is an important regulator of the transition between proliferation and differentiation. Prospero level is low in neural stem cells and their immediat
Externí odkaz:
https://doaj.org/article/111c245f4fda40cb8f0d79a59b779481