Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Ilan Winkler"'
Autor:
Lior Chatow, Adi Nudel, Iris Nesher, David Hayo Hemo, Perri Rozenberg, Hanna Voropaev, Ilan Winkler, Ronnie Levy, Zohar Kerem, Zohara Yaniv, Nadav Eyal
Publikováno v:
Life, Vol 11, Iss 4, p 290 (2021)
The activity of a new, terpene-based formulation, code-named NT-VRL-1, against Human Coronavirus (HCoV) strain 229E was evaluated in human lung fibroblasts (MRC-5 cells), with and without the addition of cannabidiol (CBD). The main constituents in th
Externí odkaz:
https://doaj.org/article/8baaa13a90ac42c2913d478988d24c31
Autor:
Rivka Cohen, Yechezkel Barenholz, Bing Mae Chen, Steve R. Roffler, Yaelle Bavli, Janos Szebeni, Ilan Winkler
Publikováno v:
Journal of Controlled Release. 306:138-148
The increasing use in the last decade of PEGylated nanodrugs such as Doxil® has seen a rise in the number of associated occurrences of hypersensitivity reactions (HSRs). These reactions (also called infusion reactions or IR), can range from harmless
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ea24390011b01cfc597022f0e004eb8
https://doi.org/10.1016/j.jconrel.2019.06.007
https://doi.org/10.1016/j.jconrel.2019.06.007
Publikováno v:
Toxicology and Applied Pharmacology. 319:59-68
5-Methoxy-2-aminoindane (MEAI) is a psychoactive compound of the aminoindane class, which in recent years has been recreationally used by many people, who reported of a mild euphoric, alcohol-like tipsy experience and reduced desire to consume alcoho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::633b0373db238c507216bac596d077eb
https://doi.org/10.1016/j.taap.2017.01.018
https://doi.org/10.1016/j.taap.2017.01.018
3,4-Methylenedioxy-N-methylamphetamine (MDMA) has been shown to be effective in the treatment of post-traumatic stress disorder (PTSD) in numerous clinical trials. In the present study, we have characterized the neurochemical binding profiles of thre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f14d0d0e65c7cfce117cdf1ac424ebd7
http://hdl.handle.net/10044/1/43622
http://hdl.handle.net/10044/1/43622
Autor:
Leah N. Klapper, Abraham Nudelman, Abraham Weizman, Herbert Y. Meltzer, Yona Geffen, Irit Gil-Ad, Mei Huang, Kinneret Savitsky, Ilan Winkler, Ada Rephaeli
Publikováno v:
European Neuropsychopharmacology. 19:1-13
Reduced brain γ-amino-butyric acid (GABA) participates in the pathogenesis of schizophrenia. GABA scarcely penetrates the brain. We evaluated the pharmacological properties of BL-1020, a novel GABA ester of perphenazine. Oral BL-1020 or perphenazine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75697832269279d174453ce7c4ccfbd0
https://doi.org/10.1016/j.euroneuro.2008.07.002
https://doi.org/10.1016/j.euroneuro.2008.07.002
Efficacy of antiepileptic isomers of valproic acid and valpromide in a rat model of neuropathic pain
Publikováno v:
British Journal of Pharmacology. 146:198-208
Antiepileptic drugs (AEDs) are often utilized in the treatment of neuropathic pain. The major AED valproic acid (VPA) is of particular interest as it is thought to engage a variety of different neural mechanisms simultaneously. However, the clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::895be1bf82f5258f9a7dc5aea86866ed
https://doi.org/10.1038/sj.bjp.0706310
https://doi.org/10.1038/sj.bjp.0706310
Autor:
Olga Kaufman, Wahid Khan, Ilan Winkler, Abraham J. Domb, Rinat Tabakman, Etgar Levy-Nissenbaum, Rajendra P. Pawar, Leah N. Klapper, Esmira Naftali
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 82(1)
Injectable biodegradable polymer poly(sebacic-co-ricinoleic acid), P(SA-RA) is currently under development for intratumoral (IT) delivery of drugs for treating solid tumors. This study presents formulation development, pharmacokinetic and efficacy st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa4e0dc6e0d40106804fa83000c28ee7
https://pubmed.ncbi.nlm.nih.gov/22732267
https://pubmed.ncbi.nlm.nih.gov/22732267
Autor:
Avi Faier, Dana Yarden, Efrat Halbfinger, Yael Gabinet, Deborah E. Shalev, Oded Ovadia, Shmuel Hess, Zhimin Xiang, Tair Lapidot, Avi Swed, Yaniv Linde, Chaim Gilon, Carrie Haskell-Luevano, Amnon Hoffman, Eli Safrai, Federico P. Portillo, Ilan Winkler
Publikováno v:
Journal of medicinal chemistry. 51(4)
The tetrapeptide sequence His-Phe-Arg-Trp, derived from melanocyte-stimulating hormone (alphaMSH) and its analogs, causes a decrease in food intake and elevates energy utilization upon binding to the melanocortin-4 receptor (MC4R). To utilize this se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07f3838dbc50ba65b50cd863d6379339
https://pubmed.ncbi.nlm.nih.gov/18220330
https://pubmed.ncbi.nlm.nih.gov/18220330
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 33(10)
The pharmacokinetics and metabolism of 2,2,3,3-tetramethylcyclopropanecarbonylurea (TMCU), a potent anticonvulsant compound, were studied in male Sprague-Dawley rats following i.v. (5 mg/kg), oral (20 mg/kg), and i.p. (20 mg/kg) administrations. Urin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af07bed14151f7c2c4cce6fbb00425f8
https://pubmed.ncbi.nlm.nih.gov/16037415
https://pubmed.ncbi.nlm.nih.gov/16037415
Efficacy of antiepileptic isomers of valproic acid and valpromide in a rat model of neuropathic pain
Autor:
Ilan, Winkler, Simcha, Blotnik, Jakob, Shimshoni, Boris, Yagen, Marshall, Devor, Meir, Bialer
Publikováno v:
British journal of pharmacology. 146(2)
Antiepileptic drugs (AEDs) are often utilized in the treatment of neuropathic pain. The major AED valproic acid (VPA) is of particular interest as it is thought to engage a variety of different neural mechanisms simultaneously. However, the clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::62ec7bb146a74cd963b78f216fa99c7d
https://pubmed.ncbi.nlm.nih.gov/15997234
https://pubmed.ncbi.nlm.nih.gov/15997234