Zobrazeno 1 - 10 of 13 pro vyhledávání: '"Il Young Ryu"'
1
Akademický článek
Identification of (Z)-2-benzylidene-dihydroimidazothiazolone derivatives as tyrosinase inhibitors: Anti-melanogenic effects and in silico studies
Autor: Heejeong Choi, Il Young Ryu, Inkyu Choi, Sultan Ullah, Hee Jin Jung, Yujin Park, YeJi Hwang, Yeongmu Jeong, Sojeong Hong, Pusoon Chun, Hae Young Chung, Hyung Ryong Moon
Publikováno v: Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 899-912 (2022)
As part of our continuous search for novel tyrosinase inhibitors, we designed 5,6-dihydroimindazo[2,1-b]thiazol-3(2H)-one (DHIT) derivatives based on the structure of MHY773; a potent tyrosinase inhibitor with a 2-iminothiazolidin-4-one template. Of
Externí odkaz: https://doaj.org/article/a5e454fd81fe488cbb1512c293b5c205
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2
Akademický článek
In silico and in vitro insights into tyrosinase inhibitors with a 2-thioxooxazoline-4-one template
Autor: Inkyu Choi, Yujin Park, Il Young Ryu, Hee Jin Jung, Sultan Ullah, Heejeong Choi, Chaeun Park, Dongwan Kang, Sanggwon Lee, Pusoon Chun, Hae Young Chung, Hyung Ryong Moon
Publikováno v: Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 37-50 (2021)
The β-phenyl-α,β-unsaturated carbonyl (PUSC) scaffold confers tyrosinase inhibitory activity, and in the present study, 16 (Z)-5-(substituted benzylidene)-3-phenyl-2-thioxooxazolidin-4-one analogues containing this scaffold were synthesized. Mushr
Externí odkaz: https://doaj.org/article/89ae3e87421146fd846ffb9e9870e0f5
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3
Akademický článek
Novel Anti-Melanogenic Compounds, (Z)-5-(Substituted Benzylidene)-4-thioxothiazolidin-2-one Derivatives: In Vitro and In Silico Insights
Autor: Heejeong Choi, Il Young Ryu, Inkyu Choi, Sultan Ullah, Hee Jin Jung, Yujin Park, Yeongmu Jeong, YeJi Hwang, Sojeong Hong, In-Soo Yoon, Hwayoung Yun, Min-Soo Kim, Jin-Wook Yoo, Yunjin Jung, Pusoon Chun, Hyung Ryong Moon
Publikováno v: Molecules, Vol 26, Iss 16, p 4963 (2021)
To confirm that the β-phenyl-α,β-unsaturated thiocarbonyl (PUSTC) scaffold, similar to the β-phenyl-α,β-unsaturated carbonyl (PUSC) scaffold, acts as a core inhibitory structure for tyrosinase, twelve (Z)-5-(substituted benzylidene)-4-thioxothi
Externí odkaz: https://doaj.org/article/81fbfe9f798140849b5c9ab47083a2ed
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4
Akademický článek
New Benzimidazothiazolone Derivatives as Tyrosinase Inhibitors with Potential Anti-Melanogenesis and Reactive Oxygen Species Scavenging Activities
Autor: Hee Jin Jung, Dong Chan Choi, Sang Gyun Noh, Heejeong Choi, Inkyu Choi, Il Young Ryu, Hae Young Chung, Hyung Ryong Moon
Publikováno v: Antioxidants, Vol 10, Iss 7, p 1078 (2021)
Thirteen (Z)-2-(substituted benzylidene)benzimidazothiazolone analogs were synthesized and evaluated for their inhibitory activity against mushroom tyrosinase. Among the compounds synthesized, compounds 1–3 showed greater inhibitory activity than k
Externí odkaz: https://doaj.org/article/29f2891bd5414372a6bd9152ca867865
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5
Akademický článek
(E)-1-(Furan-2-yl)-(substituted phenyl)prop-2-en-1-one Derivatives as Tyrosinase Inhibitors and Melanogenesis Inhibition: An In Vitro and In Silico Study
Autor: Hee Jin Jung, Sang Gyun Noh, Il Young Ryu, Chaeun Park, Ji Young Lee, Pusoon Chun, Hyung Ryong Moon, Hae Young Chung
Publikováno v: Molecules, Vol 25, Iss 22, p 5460 (2020)
A series of (E)-1-(furan-2-yl)prop-2-en-1-one derivatives (compounds 1–8) were synthesized and evaluated for their mushroom tyrosinase inhibitory activity. Among these series, compound 8 (2,4-dihydroxy group bearing benzylidene) showed potent tyros
Externí odkaz: https://doaj.org/article/7b82348561f34e1d86cb7aee3168f42f
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8
(E)-1-(Furan-2-yl)-(substituted phenyl)prop-2-en-1-one Derivatives as Tyrosinase Inhibitors and Melanogenesis Inhibition: An In Vitro and In Silico Study
Autor: Il Young Ryu, Chaeun Park, Hyung Ryong Moon, Hee Jin Jung, Sang Gyun Noh, Hae Young Chung, Pusoon Chun, Ji Young Lee
Publikováno v: Molecules
Volume 25
Issue 22
Molecules, Vol 25, Iss 5460, p 5460 (2020)
A series of (E)-1-(furan-2-yl)prop-2-en-1-one derivatives (compounds 1&ndash
8) were synthesized and evaluated for their mushroom tyrosinase inhibitory activity. Among these series, compound 8 (2,4-dihydroxy group bearing benzylidene) showed pot
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45cff544430672d2a3a76891ace12aed
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9
Novel Anti-Melanogenic Compounds, (Z)-5-(Substituted Benzylidene)-4-thioxothiazolidin-2-one Derivatives: In Vitro and In Silico Insights
Autor: Pusoon Chun, Yeongmu Jeong, Inkyu Choi, Yunjin Jung, Hyung Ryong Moon, Heejeong Choi, Min-Soo Kim, YeJi Hwang, Il Young Ryu, Jin-Wook Yoo, Sojeong Hong, Hwayoung Yun, Yujin Park, Hee Jin Jung, In-Soo Yoon, Sultan Ullah
Publikováno v: Molecules
Molecules, Vol 26, Iss 4963, p 4963 (2021)
Volume 26
Issue 16
To confirm that the β-phenyl-α,β-unsaturated thiocarbonyl (PUSTC) scaffold, similar to the β-phenyl-α,β-unsaturated carbonyl (PUSC) scaffold, acts as a core inhibitory structure for tyrosinase, twelve (Z)-5-(substituted benzylidene)-4-thioxothi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f55af31c4bf851cdd802ee03274411c6
https://doi.org/10.3390/molecules26164963
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10
New Benzimidazothiazolone Derivatives as Tyrosinase Inhibitors with Potential Anti-Melanogenesis and Reactive Oxygen Species Scavenging Activities
Autor: Inkyu Choi, Hae Young Chung, Hee Jin Jung, Hyung Ryong Moon, Sang Gyun Noh, Il Young Ryu, Dong Chan Choi, Heejeong Choi
Publikováno v: Antioxidants
Volume 10
Issue 7
Antioxidants, Vol 10, Iss 1078, p 1078 (2021)
Thirteen (Z)-2-(substituted benzylidene)benzimidazothiazolone analogs were synthesized and evaluated for their inhibitory activity against mushroom tyrosinase. Among the compounds synthesized, compounds 1–3 showed greater inhibitory activity than k
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c18fb1ea5836da7e97b1128bbabb6ae5
https://doi.org/10.3390/antiox10071078
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