Zobrazeno 1 - 10
of 160
pro vyhledávání: '"Il Sung Jang"'
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 4, Pp 1098-1100 (2025)
Externí odkaz:
https://doaj.org/article/454d90dde6ab4918bd48e3dfbbea9a90
Aberrant activation of hippocampal astrocytes causes neuroinflammation and cognitive decline in mice
Autor:
Jae-Hong Kim, Nakamura Michiko, In-Sun Choi, Yujung Kim, Ji-Young Jeong, Maan-Gee Lee, Il-Sung Jang, Kyoungho Suk
Publikováno v:
PLoS Biology, Vol 22, Iss 7 (2024)
Externí odkaz:
https://doaj.org/article/8abb766da9074f2a9fda643591680f28
Publikováno v:
BMC Anesthesiology, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background Chloral hydrate is a sedative-hypnotic drug widely used for relieving fear and anxiety in pediatric patients. However, mechanisms underlying the chloral hydrate-mediated analgesic action remain unexplored. Therefore, we investigat
Externí odkaz:
https://doaj.org/article/6c7e30d1699e45da91239261cb44f43f
Autor:
Jae Yeong Ha, Jiwon Seok, Suk-Jeong Kim, Hye-Jin Jung, Ka-Young Ryu, Michiko Nakamura, Il-Sung Jang, Su-Hyung Hong, Youngkyun Lee, Heon-Jin Lee
Publikováno v:
PLoS Pathogens, Vol 19, Iss 10, p e1011743 (2023)
Gram-negative bacteria derived extracellular vesicles (EVs), also known as outer membrane vesicles, have attracted significant attention due to their pathogenic roles in various inflammatory diseases. We recently demonstrated that EVs secreted by the
Externí odkaz:
https://doaj.org/article/1522451154c04890b0c94819baf72aef
Autor:
Michiko Nakamura, Il-Sung Jang
Publikováno v:
The Journal of Headache and Pain, Vol 23, Iss 1, Pp 1-22 (2022)
Abstract Background Growing evidence supports the important role of persistent sodium currents (INaP) in the neuronal excitability of various central neurons. However, the role of tetrodotoxin-resistant (TTX-R) Na+ channel-mediated INaP in the neuron
Externí odkaz:
https://doaj.org/article/356414b4ad7c40549d439bd586973654
Autor:
Md Habibur Rahman, Anup Bhusal, Jae-Hong Kim, Mithilesh Kumar Jha, Gyun Jee Song, Younghoon Go, Il-Sung Jang, In-Kyu Lee, Kyoungho Suk
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
Hypothalamic inflammation is involved in the pathogenesis of diabetes. The underlying mechanisms are unclear. Here, the authors show that astrocytic PDK2 ablation or inhibition attenuates hypothalamic inflammation in mouse models of diabetes.
Externí odkaz:
https://doaj.org/article/ab0aa5b82f814602985d6ffd3a2191a4
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 384:187-196
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69684a83ee3d24c08bf5f5ca95542f32
https://doi.org/10.1124/jpet.122.001346
https://doi.org/10.1124/jpet.122.001346
Publikováno v:
NeuroReport. 32:1335-1340
Objective Volatile anesthetics are widely used for general anesthesia during surgical operations. Voltage-gated Na+ channels expressed in central neurons are major targets for volatile anesthetics; but it is unclear whether these drugs modulate nativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dd1b3e2a97f123263421d8eec977086
https://doi.org/10.1097/wnr.0000000000001731
https://doi.org/10.1097/wnr.0000000000001731
Publikováno v:
GliaREFERENCES. 70(10)
Although ATP and/or adenosine derived from astrocytes are known to regulate sleep, the precise mechanisms underlying the somnogenic effects of ATP and adenosine remain unclear. We selectively expressed channelrhodopsin-2 (ChR2), a light-sensitive ion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2352d3d6ec4daefe3cee78a56546b1c
https://pubmed.ncbi.nlm.nih.gov/35638268
https://pubmed.ncbi.nlm.nih.gov/35638268
Autor:
Inkyu Lee, Habibur Rahman, Jae-Hong Kim, Il-Sung Jang, Kyoungho Suk, Mithilesh Kumar Jha, Younghoon Go, Anup Bhusal, Gyun Jee Song
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
Nature Communications
Nature Communications
Hypothalamic inflammation plays an important role in disrupting feeding behavior and energy homeostasis as well as in the pathogenesis of obesity and diabetes. Here, we show that pyruvate dehydrogenase kinase (PDK)-2 plays a role in hypothalamic infl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6373c2a693fb115ea6e6a00ea624180
http://link.springer.com/article/10.1038/s41467-020-19576-1
http://link.springer.com/article/10.1038/s41467-020-19576-1