Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Il Seon Park"'
Autor:
Md Aminul Haque, Il Seon Park
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0307213 (2024)
For the study of amyloid beta (Aβ) associated toxicity which is supposed to be the main pathological agent in Alzheimer's disease (AD), it is important to secure Aβ peptide with appropriate biological activity. However, commercial and synthetic Aβ
Externí odkaz:
https://doaj.org/article/3e149268142c4a8f9890c110c87c901c
Publikováno v:
Biochemistry and Biophysics Reports, Vol 24, Iss , Pp 100839- (2020)
Amyloid-β (Aβ), a peptide implicated in Alzheimer's disease, was shown to cause specific fragmentation of lamin proteins, which was mediated by an unidentified protease named nuclear scaffold protease (NSP) independently of caspase-6. Because caspa
Externí odkaz:
https://doaj.org/article/c71a4874127b476ab37687659aba1d67
Publikováno v:
Life, Vol 12, Iss 4, p 577 (2022)
β-Amyloid (Aβ) is a hallmark peptide of Alzheimer’s disease (AD). Herein, we explored the mechanism underlying the cytotoxicity of this peptide. Double treatment with oligomeric 42-amino-acid Aβ (Aβ42) species, which are more cytotoxic than oth
Externí odkaz:
https://doaj.org/article/74b8fa19257b4c71bc6c8faae0b7e977
Publikováno v:
Biotechnology Letters. 43:165-175
We explored the underlying mechanisms that facilitate reducing and enhancing effects of exogenous proteins on cytotoxicity of amyloid β (Aβ), a main pathogen of Alzheimer’s disease, by using an Escherichia coli chaperonin DnaK. DnaK was chosen as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cb77e8672adc3d6c7fdb716503a0d61
https://doi.org/10.1007/s10529-020-03015-8
https://doi.org/10.1007/s10529-020-03015-8
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1870:119383
Amyloid-β (Aβ) peptide, the main pathogenic peptide in Alzheimer's disease, has been shown to induce an increase in cytoplasmic calcium concentration (CCC). In the current study, we explored the cytotoxic signal transduction pathway in 42-amino-aci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f675e063c86d3f4ac3c822965896aa5d
https://doi.org/10.1016/j.bbamcr.2022.119383
https://doi.org/10.1016/j.bbamcr.2022.119383
Autor:
Md Imamul Islam, Pandian Nagakannan, Tetiana Shcholok, Fabio Contu, Sabine Mai, Benedict C Albensi, Marc R. Del Bigio, Jun‐Feng Wang, Md Golam Sharoar, Riqiang Yan, Il‐Seon Park, Eftekhar Eftekharpour
Publikováno v:
Aging Cell
Experimental and clinical therapies in the field of Alzheimer's disease (AD) have focused on elimination of extracellular amyloid beta aggregates or prevention of cytoplasmic neuronal fibrillary tangles formation, yet these approaches have been gener
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f370b6cb98cd9c158a11b10dca72bca5
https://doi.org/10.1111/acel.13531
https://doi.org/10.1111/acel.13531
Publikováno v:
Biochemistry and Biophysics Reports, Vol 24, Iss, Pp 100839-(2020)
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports
Amyloid-β (Aβ), a peptide implicated in Alzheimer's disease, was shown to cause specific fragmentation of lamin proteins, which was mediated by an unidentified protease named nuclear scaffold protease (NSP) independently of caspase-6. Because caspa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c15b774085cf96c8f9d98af3b236ac3
http://www.sciencedirect.com/science/article/pii/S2405580820301497
http://www.sciencedirect.com/science/article/pii/S2405580820301497
Publikováno v:
Biotechnology letters. 43(1)
We explored the underlying mechanisms that facilitate reducing and enhancing effects of exogenous proteins on cytotoxicity of amyloid β (Aβ), a main pathogen of Alzheimer's disease, by using an Escherichia coli chaperonin DnaK.DnaK was chosen as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aac2c978d574cabb9ebffe3c3102759b
https://pubmed.ncbi.nlm.nih.gov/33025333
https://pubmed.ncbi.nlm.nih.gov/33025333
Autor:
Md. Aminul Haque, Md. Anisuzzaman Chowdhury, Hwan Lee, Hae Ju Ko, Eun-Rhan Woo, Dong-Sung Lee, Il-Seon Park
Publikováno v:
Archives of Pharmacal Research. 40:318-327
Previous phytochemical investigations of Akebiae Caulis resulted in the isolation of triterpenes, triterpene glycosides, phenylethanoid glycosides and megastigmane glycoside. Amyloid beta (Aβ), the main component of the senile plaques detected in Al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4032057fa7e35c79d2e559b643376246
https://doi.org/10.1007/s12272-016-0885-7
https://doi.org/10.1007/s12272-016-0885-7
Publikováno v:
Amino Acids. 48:1241-1251
Sheep myeloid antimicrobial peptide-29 (SMAP-29) is a cathelicidin-related antimicrobial peptide derived from sheep myeloid cells. In order to investigate the effects of L-to-D-amino acid substitution in SMAP-29 on bacterial selectivity, membrane int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::371dfe73db29898d424a86d9811752a0
https://doi.org/10.1007/s00726-016-2170-y
https://doi.org/10.1007/s00726-016-2170-y