Zobrazeno 1 - 10
of 206
pro vyhledávání: '"Il Kyu Kim"'
Autor:
Il-Kyu Kim, Mark S. Diamond, Salina Yuan, Samantha B. Kemp, Benjamin M. Kahn, Qinglan Li, Jeffrey H. Lin, Jinyang Li, Robert J. Norgard, Stacy K. Thomas, Maria Merolle, Takeshi Katsuda, John W. Tobias, Timour Baslan, Katerina Politi, Robert H. Vonderheide, Ben Z. Stanger
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Acquired resistance to immunotherapy remains a critical yet incompletely understood biological mechanism. Here, using a mouse model of pancreatic ductal adenocarcinoma (PDAC) to study tumor relapse following immunotherapy-induced responses,
Externí odkaz:
https://doaj.org/article/96e408eb89f447649478a14b903b0f6a
Autor:
Amina Ouzar, Il-Kyu Kim
Publikováno v:
Water Science and Technology, Vol 86, Iss 11, Pp 2794-2807 (2022)
Tetracyclines (TCs) are often discussed as one of the emerging contaminants detected in water matrices and studied for their persistence towards conventional water treatment technologies. In this work, the treatment of TC in aqueous solutions with no
Externí odkaz:
https://doaj.org/article/02dc66a308ec4183bb22611e67cf78b7
Autor:
Sang-Min Lee, Il-Kyu Kim
Publikováno v:
대한환경공학회지, Vol 43, Iss 1, Pp 66-78 (2021)
Objectives:To estimate algae of Chlorophyll-a (Chl-a) with machine learning algorithms, water quality and quantity data of the downstream region of Nakdong River area were used. Methods:At first, the correlation analysis was studied about Chl-a, wat
Externí odkaz:
https://doaj.org/article/7cd83661d5a54b81b820579aee6a35bd
Autor:
Samantha B. Kemp, Noah Cheng, Nune Markosyan, Rina Sor, Il-Kyu Kim, Jill Hallin, Jason Shoush, Liz Quinones, Natalie V. Brown, Jared B. Bassett, Nikhil Joshi, Salina Yuan, Molly Smith, William P. Vostrejs, Kia Z. Perez-Vale, Benjamin Kahn, Feiyan Mo, Timothy R. Donahue, Caius G. Radu, Cynthia Clendenin, James G. Christensen, Robert H. Vonderheide, Ben Z. Stanger
Publikováno v:
Cancer Discovery. 13:298-311
Mutations in the KRAS oncogene are found in more than 90% of patients with pancreatic ductal adenocarcinoma (PDAC), with Gly-to-Asp mutations (KRASG12D) being the most common. Here, we tested the efficacy of a small-molecule KRASG12D inhibitor, MRTX1
Autor:
Seongmin Cho, Sang Bum Kim, Youngjin Lee, Ee Chan Song, Uijoo Kim, Hyeong Yun Kim, Ji Hun Suh, Peter C Goughnour, YounHa Kim, Ina Yoon, Na Young Shin, Doyeun Kim, Il-Kyu Kim, Song Yee Jang, Myung Hee Kim
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Background The generation of antigen-specific cytotoxic T lymphocyte (CTL) responses is required for successful cancer vaccine therapy. In this regard, ligands of Toll-like receptors (TLRs) have been suggested to activate adaptive immune responses by
Externí odkaz:
https://doaj.org/article/86e4d178fe8d4592938b1225a02f36e8
Publikováno v:
Toxics, Vol 9, Iss 12, p 327 (2021)
Two of the most hazardous benzene derivatives (HBD) that have polluted the aquatic environment are bromobenzene and chlorobenzene. Ferrate can degrade various pollutants quickly and efficiently without producing harmful byproducts. This study aims to
Externí odkaz:
https://doaj.org/article/d46533a5d79c4540a5cc5e7bf77df919
Autor:
Hyungseok Seo, Insu Jeon, Byung-Seok Kim, Myunghwan Park, Eun-Ah Bae, Boyeong Song, Choong-Hyun Koh, Kwang-Soo Shin, Il-Kyu Kim, Kiyoung Choi, Taegwon Oh, Jiyoun Min, Byung Soh Min, Yoon Dae Han, Suk-Jo Kang, Sang Joon Shin, Yeonseok Chung, Chang-Yuil Kang
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Loss of major histocompatibility complex MHC-I expression contributes to cancer immune evasion. Here, the authors show that, in both mice and humans, MHC-I downregulation is associated with the induction of NK-cell exhaustion and that IL-21 restores
Externí odkaz:
https://doaj.org/article/2bd96612eae447d095ca7886cae7e6ec
Autor:
Nguyen Minh Hoang, Il-Kyu Kim
Publikováno v:
Journal of the Korean Society of Water and Wastewater. 36:167-175
Autor:
Kwang-Soo Shin, Insu Jeon, Byung-Seok Kim, Il-Kyu Kim, Young-Jun Park, Choong-Hyun Koh, Boyeong Song, Jeong-Mi Lee, Jiyoung Lim, Eun-Ah Bae, Hyungseok Seo, Young Ho Ban, Sang-Jun Ha, Chang-Yuil Kang
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Monocyte-derived dendritic cells (moDCs) have been shown to robustly expand during infection; however, their roles in anti-infectious immunity remain unclear. Here, we found that moDCs were dramatically increased in the secondary lymphoid organs duri
Externí odkaz:
https://doaj.org/article/c9487de59adf431798a7495f20d89d46
Autor:
Ben Z. Stanger, Robert H. Vonderheide, James G. Christensen, Cynthia Clendenin, Caius G. Radu, Timothy R. Donahue, Feiyan Mo, Benjamin Kahn, Kia Z. Perez-Vale, William P. Vostrejs, Molly Smith, Salina Yuan, Nikhil Joshi, Jared B. Bassett, Natalie V. Brown, Liz Quinones, Jason Shoush, Jill Hallin, Il-Kyu Kim, Rina Sor, Nune Markosyan, Noah Cheng, Samantha B. Kemp
MRTX1133 selectively inhibits KRASG12D and downstream MAPK signaling in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39958610ccaffa414aa6c8d481568e7b
https://doi.org/10.1158/2159-8290.22541985
https://doi.org/10.1158/2159-8290.22541985