Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Il'icheva IA"'
Publikováno v:
Biophysics. 65:426-432
This review is dedicated to the memory of Dr. Sergei L’vovich Grokhovsky, who was a distinguished scientists and experimenter; it briefly describes one aspect of his multifaceted research activity. Gro-khovsky was the first to describe the specific
Autor:
Iren R. Umarova, L. A. Uroshlev, R. V. Polozov, Fyodor A. Kondrashov, Il'icheva Ia, Yury D. Nechipurenko, L. A. Panchenko, Eldar T. Abdullaev, S. L. Grokhovsky
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-5 (2020)
Scientific Reports
Scientific Reports
In the course of sample preparation for Next Generation Sequencing (NGS), DNA is fragmented by various methods. Fragmentation shows a persistent bias with regard to the cleavage rates of various dinucleotides. With the exception of CpG dinucleotides
Publikováno v:
Biomolecules, Vol 10, Iss 552, p 552 (2020)
Biomolecules
Biomolecules
Nucleoside phosphorylases catalyze the reversible phosphorolysis of nucleosides to heterocyclic bases, giving α-d-ribose-1-phosphate or α-d-2-deoxyribose-1-phosphate. These enzymes are involved in salvage pathways of nucleoside biosynthesis. The le
Autor:
S. L. Grokhovsky, Yu. D. Nechipurenko, Il'icheva Ia, M. V. Khodikov, Maria Poptsova, D. Yu. Nechipurenko
Publikováno v:
Biophysics. 59:861-868
In this study, we performed a simulation of stretching dynamics in double-stranded DNA fragments in a high-gradient liquid flow in the neighborhood of collapsing cavitation bubbles. We used calculated profiles of elastic tension along the polymer fra
Autor:
D. Yu. Nechipurenko, Il'icheva Ia, S. L. Grokhovsky, M. V. Golovkin, R. V. Polozov, Yu. D. Nechipurenko, L. A. Panchenko
Publikováno v:
Biophysics. 58:27-36
We investigated a phenomenon of ultrasonic cleavage of DNA complexed with transition metal cations Ag(I), Cu(II) and Hg(II). We found the statistically significant dependence of relative intensity of cleavage on cation type and concentration. Each ca
Autor:
Yury D. Nechipurenko, Dmitry Yu. Nechipurenko, M. V. Golovkin, S. L. Grokhovsky, Il'icheva Ia, R. V. Polozov, L. A. Panchenko
Publikováno v:
Biophysical Journal. 100:117-125
We investigated the phenomenon of ultrasonic cleavage of DNA by analyzing a large set of cleavage patterns of DNA restriction fragments using polyacrylamide gel electrophoresis. The cleavage intensity of individual phosphodiester bonds was found to d
Autor:
Mikhail Viktorovich Golovkin, R. V. Polozov, Dmitrii Yurievich Nechipurenko, Yurii Dmitrievich Nechipurenko, Il'icheva Ia, S. L. Grokhovsky, L. A. Panchenko
Publikováno v:
Компьютерные исследования и моделирование, Vol 2, Iss 4, Pp 419-428 (2010)
Recently we have developed a new method for studying DNA based on ultrasound - induced cleavage of DNA sugar-phosphate backbone. Relative cleavage rates of the phosphodiester bonds in all 16 dinucleotides have been determined. The increased amount of
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 27:391-397
Structural properties of nicked dsDNA have been an object of numerous studies due to their special role in reparation processes. Here we report experimental results covering ultrasound irradiation of a nicked dsDNA fragments. We have quantitatively e
Autor:
D. Yu. Nechipurenko, R. V. Polozov, Il'icheva Ia, Yu. D. Nechipurenko, L. A. Panchenko, S. L. Grokhovskii, M. V. Golovkin
Publikováno v:
Journal of Structural Chemistry. 50:1007-1013
The site effect (the dependence of the band intensity on the band position of gel) is the key factor that should be taken into account in quantitative analysis of the images of high-resolution electrophoretic gels containing many bands. We developed
Autor:
Mikhail Viktorovich Golovkin, Il'icheva Ia, L. A. Panchenko, S. L. Grokhovsky, R. V. Polozov, Yurii Dmitrievich Nechipurenko, Dmitrii Yurievich Nechipurenko
Publikováno v:
Computer Research and Modeling. 1:287-295