Zobrazeno 1 - 10
of 171
pro vyhledávání: '"Ikyon Kim"'
Publikováno v:
ACS Omega, Vol 9, Iss 36, Pp 38126-38141 (2024)
Externí odkaz:
https://doaj.org/article/06dfb7eb9ab144f9aaa30c6b72fe67df
Autor:
Hee Yang Lee, Soljee Yoon, Jeong Hwa Lee, Keunwan Park, Youngeun Jung, Illhwan Cho, Donghee Lee, Jisu Shin, Kyeonghwan Kim, Sunmi Kim, Jimin Kim, Koeun Kim, Seung Hoon Han, Seong Muk Kim, Hye Ju Kim, Hye Yun Kim, Ikyon Kim, Young Soo Kim
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-19 (2022)
Abstract Background Aggregated amyloid-β (Aβ) is considered a pathogenic initiator of Alzheimer’s disease (AD), in strong association with tau hyperphosphorylation, neuroinflammation, synaptic dysfunction, and cognitive decline. As the removal of
Externí odkaz:
https://doaj.org/article/4e33b2fd1a2542f2aa38952a5a6ba0d5
Autor:
Yechan Lee, Sunhee Lee, Younho Lee, Doona Song, So-Hyeon Park, Jieun Kim, Wan Namkung, Ikyon Kim
Publikováno v:
Pharmaceuticals, Vol 17, Iss 2, p 231 (2024)
The epidermal growth factor receptor (EGFR), also known as ErbB1 and HER1, belongs to the receptor tyrosine kinase family. EGFR serves as the primary driver in non-small-cell lung cancer (NSCLC) and is a promising therapeutic target for NSCLC. In thi
Externí odkaz:
https://doaj.org/article/25afb50b92b64f0a88bdb9c7b8689080
Publikováno v:
Pharmaceuticals, Vol 15, Iss 11, p 1395 (2022)
A highly efficient approach to a new indolizine scaffold fused with pyrrolo[1,2-c]pyrimidine was achieved via one-pot three-component coupling followed by an oxidative cyclization reaction. The simple two-step sequence allowed rapid access to various
Externí odkaz:
https://doaj.org/article/6a127f732f9f46eb93e52b37b12145f4
Autor:
Dileep Kumar Singh, Ikyon Kim
Publikováno v:
ARKIVOC, Vol 2019, Iss 3, Pp 8-21 (2019)
Externí odkaz:
https://doaj.org/article/d6ec34d4d4da4426a010835e65e08a82
Autor:
DaWon Kim, Jeong Hwa Lee, Hye Yun Kim, Jisu Shin, Kyeonghwan Kim, Sejin Lee, Jinwoo Park, Ikyon Kim, YoungSoo Kim
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0250194 (2021)
[This corrects the article DOI: 10.1371/journal.pone.0243041.].
Externí odkaz:
https://doaj.org/article/f6f9933df90d4fdd9d969875cb9151e8
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 12, Iss 1, Pp 2689-2693 (2016)
The recognition of the local symmetric image within benzofuran-based natural oligostilbenoids guided us to design a modular synthetic approach to these molecules by utilizing a three-step sequence consisting of Sonogashira coupling, iodocyclization,
Externí odkaz:
https://doaj.org/article/40269489b7084753ab2d9115eb34e598
Autor:
Eunji Kim, Young-Jin Son, Yanyan Yang, Ting Shen, Ikyon Kim, Adithan Aravinthan, Jong-Hoon Kim, Jae Youl Cho
Publikováno v:
Molecules, Vol 21, Iss 4, p 508 (2016)
Inflammation is the protective action of our bodies against external pathogens by recognition of pathogen-associated molecular patterns (PAMPs) via pattern recognition receptors (PRRs). Proper regulation of inflammatory responses is required to maint
Externí odkaz:
https://doaj.org/article/29b0a11847df40f9a3fd9d406feb2193
Publikováno v:
ACS Omega. 8:16131-16144
Publikováno v:
Organic & Biomolecular Chemistry. 21:3881-3895
Divergent synthesis of two types of indolizines is described via a step-dependent assembly of pyridine-2-acetonitriles, arylglyoxals, and TMSCN.