Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Ikuyo Ichi"'
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-10 (2024)
Abstract Two mammalian homologs of systemic RNA interference defective protein 1 (SID-1) (SIDT1/2) are suggested to function as double-stranded RNA (dsRNA) transporters for extracellular dsRNA uptake or for release of incorporated dsRNA from lysosome
Externí odkaz:
https://doaj.org/article/63c4d99fbbad47928381bb7d7daff641
Autor:
Mika Sawada, Kanako Ohkuma, Masakazu Aihara, Shunsuke Doi, Rie Sekine, Tetsuji Kaneko, Satoshi Iimuro, Ikuyo Ichi, Satoshi Usami, Kazuhiko Ohe, Toshimasa Yamauchi, Naoto Kubota
Publikováno v:
Journal of Diabetes Investigation, Vol 14, Iss 2, Pp 321-328 (2023)
ABSTRACT Aims/Introduction To evaluate the impact of the COVID‐19 pandemic on the glycemic control, eating habits, and body composition of people with diabetes mellitus; to identify the determinants of worsening glycemic control in people with diab
Externí odkaz:
https://doaj.org/article/3b506b058920418a96ab862a5acc69e2
Autor:
Tomoki Uchikawa, Tetsuya Matoba, Takuro Kawahara, Isashi Baba, Shunsuke Katsuki, Jun-ichiro Koga, Yu Hashimoto, Ryo Yamasaki, Ikuyo Ichi, Hidetaka Akita, Hiroyuki Tsutsui
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Emerging evidence suggests that 7-ketocholesterol (7-KC), one of the most abundant dietary oxysterols, causes inflammation and cardiovascular diseases. Here we show the deteriorating effects of dietary 7-KC on myocardial ischemia–reperfusi
Externí odkaz:
https://doaj.org/article/1ffebf7ae76f430d94447418acaf13f1
Publikováno v:
Nutrients, Vol 16, Iss 1, p 38 (2023)
We previously reported that piceatannol (PIC) had an anti-obesity effect only in ovariectomized (OVX) postmenopausal obesity mice. PIC was found to induce the phosphorylation of hormone-sensitive lipase (pHSL) in OVX mice. To elucidate the mechanism
Externí odkaz:
https://doaj.org/article/fefb3027b90a4ce4a16df2c28ec89d0c
Autor:
Yusuke Akiyama, Shunsuke Katsuki, Tetsuya Matoba, Yasuhiro Nakano, Susumu Takase, Soichi Nakashiro, Mitsutaka Yamamoto, Yasushi Mukai, Shujiro Inoue, Keiji Oi, Taiki Higo, Masao Takemoto, Nobuhiro Suematsu, Kenichi Eshima, Kenji Miyata, Makoto Usui, Kenji Sadamatsu, Toshiaki Kadokami, Kiyoshi Hironaga, Ikuyo Ichi, Koji Todaka, Junji Kishimoto, Hiroyuki Tsutsui
Publikováno v:
Nutrients, Vol 15, Iss 13, p 2997 (2023)
Oxysterols have been implicated in the pathogenesis of cardiovascular diseases. Serum levels of oxysterols could be positively correlated with cholesterol absorption and synthesis. However, physiological regulation of various serum oxysterols is larg
Externí odkaz:
https://doaj.org/article/4ade8779f9ba4675b38290dff44df39a
Autor:
Kotoko Arisawa, Miyuki Kaneko, Ayumi Matsuoka, Natsuki Ozawa, Rie Kawawa, Tomoko Ishikawa, Ikuyo Ichi, Yoko Fujiwara
Publikováno v:
Nutrients, Vol 15, Iss 6, p 1374 (2023)
Postmenopausal women have a higher susceptibility to obesity and chronic disease. Piceatannol (PIC), a natural analog of resveratrol, was reported to inhibit adipogenesis and to have an antiobesity effect. In this study, PIC’s effect on postmenopau
Externí odkaz:
https://doaj.org/article/ad9143dd32fa42f5857c30d3413348a9
Autor:
Ayami Saga, Masahiro Koseki, Kotaro Kanno, Jiuyang Chang, Tomoaki Higo, Daisuke Okuzaki, Takeshi Okada, Hiroyasu Inui, Masumi Asaji, Katsunao Tanaka, Takashi Omatsu, Sae Nishihara, Yinghong Zhu, Kaori Ito, Hiroaki Hattori, Ikuyo Ichi, Yoshihiro Kamada, Masafumi Ono, Toshiji Saibara, Tohru Ohama, Shungo Hikoso, Makoto Nishida, Shizuya Yamashita, Yasushi Sakata
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 15855 (2022)
Patients with psoriasis are at a higher risk of developing nonalcoholic fatty liver disease. We previously identified an oxidized derivative of cholesterol, 7-ketocholesterol (7KC), in diet-induced steatohepatitic mice. Here, we investigated whether
Externí odkaz:
https://doaj.org/article/88e94a5424854136909f75e78e0c1f16
Autor:
Jiuyang Chang, Masahiro Koseki, Ayami Saga, Kotaro Kanno, Tomoaki Higo, Daisuke Okuzaki, Takeshi Okada, Hiroyasu Inui, Katsunao Tanaka, Masumi Asaji, Yinghong Zhu, Yoshihiro Kamada, Masafumi Ono, Toshiji Saibara, Ikuyo Ichi, Tohru Ohama, Makoto Nishida, Shizuya Yamashita, Yasushi Sakata
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2021)
Non-alcoholic fatty liver disease is strongly associated with obese and type 2 diabetes. It has been reported that an oxidized cholesterol, 7-ketocholesterol (7KC), might cause inflammatory response in macrophages and plasma 7KC concentration were hi
Externí odkaz:
https://doaj.org/article/9d4183de3c844781921e3dc272be5b86
Autor:
Yu Takahashi, Akihiro Shinoda, Norihiko Furuya, Eri Harada, Naoto Arimura, Ikuyo Ichi, Yoko Fujiwara, Jun Inoue, Ryuichiro Sato
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64605 (2013)
Sterol regulatory element-binding protein-1 (SREBP-1) has been thought to be a critical factor that assists adipogenesis. During adipogenesis SREBP-1 stimulates lipogenic gene expression, and peroxisome proliferator-activated receptor γ (PPARγ) enh
Externí odkaz:
https://doaj.org/article/b7f03d56cf454dc59cd10377c7b4df8e
Autor:
Kanade Tatsumi, Takuji Ichino, Natsumi Isaka, Akifumi Sugiyama, Eiko Moriyoshi, Yozo Okazaki, Yasuhiro Higashi, Masataka Kajikawa, Yoshinori Tsuji, Hideya Fukuzawa, Kiminori Toyooka, Mayuko Sato, Ikuyo Ichi, Koichiro Shimomura, Hiroyuki Ohta, Kazuki Saito, Kazufumi Yazaki
Publikováno v:
Journal of Experimental Botany. 74:104-117
Plants produce a large variety of lipophilic metabolites, many of which are secreted by cells and accumulated in apoplasts. These compounds often play a role to protect plants from environmental stresses. However, little is known about how these lipo