Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Ikuroh, Ohsawa"'
Autor:
Toshiyuki Aokage, Masumi Iketani, Mizuki Seya, Ying Meng, Kohei Ageta, Hiromichi Naito, Atsunori Nakao, Ikuroh Ohsawa
Publikováno v:
Experimental Gerontology, Vol 180, Iss , Pp 112270- (2023)
Introduction: With the global population aging, there is an increased prevalence of sepsis among the elderly, a demographic particularly susceptible to inflammation. This study aimed to evaluate the therapeutic potential of hydrogen gas, known for it
Externí odkaz:
https://doaj.org/article/0b8425f69a304035a3254a82c404e65f
Drinking hydrogen water improves photoreceptor structure and function in retinal degeneration 6 mice
Autor:
Tsutomu Igarashi, Ikuroh Ohsawa, Maika Kobayashi, Kai Miyazaki, Toru Igarashi, Shuhei Kameya, Asaka Lee Shiozawa, Yasuhiro Ikeda, Yoshitaka Miyagawa, Mashito Sakai, Takashi Okada, Iwao Sakane, Hiroshi Takahashi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Retinitis pigmentosa (RP) is a genetically heterogeneous group of inherited retinal disorders involving the progressive dysfunction of photoreceptors and the retinal pigment epithelium, for which there is currently no treatment. The rd6 mous
Externí odkaz:
https://doaj.org/article/559262fae9124ee9856ebc38e123867a
Autor:
Toshiyuki Aokage, Mizuki Seya, Takahiro Hirayama, Tsuyoshi Nojima, Masumi Iketani, Michiko Ishikawa, Yasuhiro Terasaki, Akihiko Taniguchi, Nobuaki Miyahara, Atsunori Nakao, Ikuroh Ohsawa, Hiromichi Naito
Publikováno v:
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-15 (2021)
Abstract Background Acute respiratory distress syndrome, which is caused by acute lung injury, is a destructive respiratory disorder caused by a systemic inflammatory response. Persistent inflammation results in irreversible alveolar fibrosis. Becaus
Externí odkaz:
https://doaj.org/article/58f7a2d72e1948ee941a0ae606f85866
Autor:
Kyojiro Kawakami, Yasunori Fujita, Taku Kato, Kengo Horie, Takuya Koie, Keitaro Umezawa, Hiroki Tsumoto, Yuri Miura, Yasuo Katagiri, Tatsuhiko Miyazaki, Ikuroh Ohsawa, Kosuke Mizutani, Masafumi Ito
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract We aimed to develop a sandwich ELISA to detect prostate-specific membrane antigen (PSMA) on small extracellular vesicles (EVs) using T-cell immunoglobulin domain and mucin domain-containing protein 4 (Tim4) as a capture molecule for EVs and
Externí odkaz:
https://doaj.org/article/648dd70978a8435eb6429fb1ecaa1541
Autor:
Takeshi Arima, Tsutomu Igarashi, Masaaki Uchiyama, Maika Kobayashi, Ikuroh Ohsawa, Akira Shimizu, Hiroshi Takahashi
Publikováno v:
International Journal of Ophthalmology, Vol 13, Iss 8, Pp 1173-1179 (2020)
AIM: To investigate the effects of hydrogen (H2) on Cu, Zn superoxide dismutase (SOD1) activation in a rat model of corneal alkali burn. METHODS: In each rat, one cornea was subjected to alkali exposure. Physiological saline (saline group) or H2-dis
Externí odkaz:
https://doaj.org/article/a560c2bae1464f1eb3b8cdb7b3e26665
Autor:
Yosuke Fukutani, Yuko Nakamura, Nonoko Muto, Shunta Miyanaga, Reina Kanemaki, Kentaro Ikegami, Keiichi Noguchi, Ikuroh Ohsawa, Hiroaki Matsunami, Masafumi Yohda
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1, p 277 (2021)
Vertebrate animals detect odors through olfactory receptors (ORs), members of the G protein-coupled receptor (GPCR) family. Due to the difficulty in the heterologous expression of ORs, studies of their odor molecule recognition mechanisms have progre
Externí odkaz:
https://doaj.org/article/2f0a9919018b4948be34a818d9e0a6f6
Autor:
Yasunori Fujita, Shoji Shinkai, Yu Taniguchi, Yuri Miura, Masashi Tanaka, Ikuroh Ohsawa, Akihiko Kitamura, Masafumi Ito
Publikováno v:
The Journals of Gerontology: Series A.
Background Serum growth differentiation factor 15 (GDF15) is associated with age-related adverse outcomes. However, renal function has not been thoroughly evaluated in studies addressing the association between GDF15 and mortality. We aimed to clarif
Publikováno v:
Medical gas research. 13(3)
Molecular hydrogen (H
Autor:
Ikuroh Ohsawa, Yuri Miura, Kyojiro Kawakami, Yasuo Katagiri, Hiroki Tsumoto, Kengo Horie, Keitaro Umezawa, Masafumi Ito, Tatsuhiko Miyazaki, Kosuke Mizutani, Takuya Koie, Yasunori Fujita, Taku Kato
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
We aimed to develop a sandwich ELISA to detect prostate-specific membrane antigen (PSMA) on small extracellular vesicles (EVs) using T-cell immunoglobulin domain and mucin domain-containing protein 4 (Tim4) as a capture molecule for EVs and to evalua
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0176992 (2017)
Inhalation of molecular hydrogen (H2) gas ameliorates oxidative stress-induced acute injuries in the brain. Consumption of water nearly saturated with H2 also prevents chronic neurodegenerative diseases including Parkinson's disease in animal and cli
Externí odkaz:
https://doaj.org/article/8b8b95d60c9d43bc8149687deaf57e7b