Zobrazeno 1 - 10
of 746
pro vyhledávání: '"Ikuro, Abe"'
Autor:
Huibin Wang, Ikuro Abe
Publikováno v:
Tetrahedron Chem, Vol 12, Iss , Pp 100112- (2024)
Halogenation significantly enhances the biological activity, stability, and solubility of organic molecules, and thus is a crucial modification in the biotechnology and pharmaceutical industries. Halogenases, the core enzymes responsible for this tra
Externí odkaz:
https://doaj.org/article/a5b4096dc4eb4a719c25fb0be50ea38a
Autor:
Shao-Yang Li, Gao-Qian Wang, Liang Long, Jia-Ling Gao, Zheng-Qun Zhou, Yong-Heng Wang, Jian-Ming Lv, Guo-Dong Chen, Dan Hu, Ikuro Abe, Hao Gao
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Lycibarbarspermidines are unusual phenolamide glycosides characterized by a dicaffeoylspermidine core with multiple glycosyl substitutions, and serve as a major class of bioactive ingredients in the wolfberry. So far, little is known about t
Externí odkaz:
https://doaj.org/article/1566b6ddaa074074b8179b7c1589039f
Autor:
Takahiro Mori, Ikuro Abe
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 18, Iss 1, Pp 707-721 (2022)
Endoperoxide natural products are widely distributed in nature and exhibit various biological activities. Due to their chemical features, endoperoxide and endoperoxide-derived secondary metabolites have attracted keen attention in the field of natura
Externí odkaz:
https://doaj.org/article/a3c25d432b624678bd64a32db81af901
Publikováno v:
Engineering Microbiology, Vol 3, Iss 1, Pp 100062- (2023)
Fe(II)/α-ketoglutarate (αKG)-dependent oxygenases catalyze the oxidative modification of various molecules, from DNA, RNA, and proteins to primary and secondary metabolites. They also catalyze a variety of biochemical reactions, including hydroxyla
Externí odkaz:
https://doaj.org/article/1fb0d1ddb08642ac907e2f05df37820b
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Non-heme iron and α-ketoglutarate-dependent (Fe/αKG) oxygenases have attracted attention for their application as biocatalysts due to their flexibility and high efficiency. Here, the authors show the biochemical and structural characterizations of
Externí odkaz:
https://doaj.org/article/e00ab63426854cd7a09fe5b5accee271
Autor:
Xiao-Hui Wang, Bo-Wen Gao, Yu Nakashima, Takahiro Mori, Zhong-Xiu Zhang, Takeshi Kodama, Yuan-E Lee, Ze-Kun Zhang, Chin-Piow Wong, Qian-Qian Liu, Bo-Wen Qi, Juan Wang, Jun Li, Xiao Liu, Ikuro Abe, Hiroyuki Morita, Peng-Fei Tu, She-Po Shi
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
2-(2-Phenylethyl)chromones (PECs) contribute to the distinctive fragrance of agarwood. Here the authors identify a diarylpentanoid-producing polyketide synthase from Aquilaria sinensis and show how it catalyzes PEC formation.
Externí odkaz:
https://doaj.org/article/b3be7674712c43989f1d644bfab8575f
Autor:
Takahiro Mori, Takuto Kumano, Haibing He, Satomi Watanabe, Miki Senda, Toshio Moriya, Naruhiko Adachi, Sanae Hori, Yuzu Terashita, Masato Kawasaki, Yoshiteru Hashimoto, Takayoshi Awakawa, Toshiya Senda, Ikuro Abe, Michihiko Kobayashi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
In C-glycosides the sugar moiety is linked through a carbon-carbon bond to the non-sugar moiety, which can be cleaved by intestinal microbes. Here, the authors use bioinformatics analysis to identify C-glycoside deglycosidase enzymes in intestinal an
Externí odkaz:
https://doaj.org/article/be2834e7f7604e8f81be75ba24bda5b8
Autor:
Huibin Wang, Ikuro Abe
Publikováno v:
Organic & Biomolecular Chemistry; 5/14/2024, Vol. 22 Issue 18, p3559-3583, 25p
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Many endoperoxide-containing natural products have been isolated, but the biosynthesis of the endoperoxides remains unclear. Here, the authors report the structural and functional analysis of the NvfI endoperoxidase that catalyzes the formation of fu
Externí odkaz:
https://doaj.org/article/8ecfd9aaea274ad3882afbb439bc7ed7
Autor:
He-Ping Chen, Ikuro Abe
Publikováno v:
Synthetic and Systems Biotechnology, Vol 6, Iss 2, Pp 51-62 (2021)
Prenyltransferase (PTase) enzymes play crucial roles in natural product biosynthesis by transferring isoprene unit(s) to target substrates, thereby generating prenylated compounds. The prenylation step leads to a diverse group of natural products wit
Externí odkaz:
https://doaj.org/article/2ce0a44efbef4b6c835c94bea8d6ae38