Zobrazeno 1 - 10
of 319
pro vyhledávání: '"Ikuo Sekine"'
Autor:
Takehito Shukuya, Kazuhisa Takahashi, Yasushi Shintani, Keita Miura, Ikuo Sekine, Koichi Takayama, Akira Inoue, Isamu Okamoto, Katsuyuki Kiura, Tomoya Kawaguchi, Nobuyuki Yamamoto, Etsuo Miyaoka, Ichiro Yoshino, Hiroshi Date
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 3, Pp 1274-1285 (2023)
Abstract Background Cancer cachexia is a syndrome that does not fully recover with nutritional support and causes appetite loss and body weight loss. It worsens a patient's quality of life and prognosis. In this study, the epidemiology of cachexia in
Externí odkaz:
https://doaj.org/article/68660320fdbd4d5392bc951bfce4c97d
Autor:
Eriko Miyawaki, Hirotsugu Kenmotsu, Yasushi Shintani, Ikuo Sekine, Takehito Shukuya, Koichi Takayama, Akira Inoue, Isamu Okamoto, Katsuyuki Kiura, Kazuhisa Takahashi, Nobuyuki Yamamoto, Tomoya Kawaguchi, Etsuo Miyaoka, Ichiro Yoshino, Hiroshi Date
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Platinum-based chemoradiotherapy is the standard treatment for unresectable stage III non-small-cell lung cancer (NSCLC). However, few studies have evaluated the efficacy of subsequent chemotherapy for relapsed NSCLC following pla
Externí odkaz:
https://doaj.org/article/b01798b87eb54143beeca5d75aed8d59
Autor:
Kayoko Ohnishi, Hitoshi Ishikawa, Kensuke Nakazawa, Toshihiro Shiozawa, Yutaro Mori, Masatoshi Nakamura, Toshiyuki Okumura, Ikuo Sekine, Nobuyuki Hizawa, Hideyuki Sakurai
Publikováno v:
Thoracic Cancer, Vol 12, Iss 9, Pp 1320-1327 (2021)
Abstract Background To evaluate the long‐term outcomes of high‐dose (74 GyE) proton beam therapy (PBT) with concurrent chemotherapy for stage III non‐small cell lung cancer (NSCLC). Methods Between July 2007 and March 2018, 45 patients with sta
Externí odkaz:
https://doaj.org/article/73fb999c530c4c8191b3021306ed1cfa
Autor:
Shinsuke Kitazawa, Naohiro Kobayashi, Sho Ueda, Yuki Enomoto, Yoshiaki Inoue, Toshihiro Shiozawa, Ikuo Sekine, Hitomi Kawai, Masayuki Noguchi, Yukio Sato
Publikováno v:
Thoracic Cancer, Vol 11, Iss 10, Pp 3024-3028 (2020)
Endobronchial‐invasive lung cancers are generally diagnosed at advanced stages and may require emergency treatment for airway obstruction. Stent implantation is a common intervention for such obstructed airways but certain subsets of patients canno
Externí odkaz:
https://doaj.org/article/fdc3bc7cf2e34e72a6ba4d5746b55522
Autor:
Yuka Aida, Kensuke Nakazawa, Toshihiro Shiozawa, Ryoko Ogawa, Takumi Kiwamoto, Yuko Morishima, Toru Sakamoto, Ikuo Sekine, Nobuyuki Hizawa
Publikováno v:
Case Reports in Oncology, Vol 12, Iss 2, Pp 613-620 (2019)
Small-cell lung cancer (SCLC) is highly sensitive to platinum-based chemotherapy. However, its indication in patients with a poor performance status (PS) at initial diagnosis is controversial. We retrospectively reviewed all clinical courses of patho
Externí odkaz:
https://doaj.org/article/eb912564c36a40df80d6ca712b0e4b6b
Autor:
Yiyang Qin, Ikuo Sekine, Michiko Hanazono, Takao Morinaga, Mengmeng Fan, Yuichi Takiguchi, Yuji Tada, Masato Shingyoji, Naoto Yamaguchi, Masatoshi Tagawa
Publikováno v:
Molecular Oncology, Vol 13, Iss 6, Pp 1419-1432 (2019)
Pemetrexed (PEM) inhibits DNA and RNA synthesis and is currently one of the first‐line agents for mesothelioma. PEM suppresses the activities of several enzymes involved in purine and pyrimidine synthesis, and elevated activity of these enzymes in
Externí odkaz:
https://doaj.org/article/455ab0add9c64db28e0ba6554b010481
Autor:
Toshihiro Shiozawa, Ikuo Sekine, Yuka Aida, Hiroko Watanabe, Kensuke Nakazawa, Koichi Kurishima, Hiroaki Satoh, Nobuyuki Hizawa
Publikováno v:
Case Reports in Oncology, Vol 11, Iss 3, Pp 622-632 (2018)
Background: Sensitive-relapsed small-cell lung cancer (SCLC) is thought to be sensitive to chemotherapy; therefore, second-line chemotherapy is recommended. Although platinum rechallenge is performed in the second-line chemotherapy for sensitive-rela
Externí odkaz:
https://doaj.org/article/a8ea2d926ab74fdabce18a76116d375a
Autor:
Yiyang Qin, Ikuo Sekine, Mengmeng Fan, Yuichi Takiguchi, Yuji Tada, Masato Shingyoji, Michiko Hanazono, Naoto Yamaguchi, Masatoshi Tagawa
Publikováno v:
Cancer Cell International, Vol 17, Iss 1, Pp 1-11 (2017)
Abstract Background Pemetrexed (PEM) is an anti-cancer agent targeting DNA and RNA synthesis, and clinically in use for mesothelioma and non-small cell lung carcinoma. A mechanism of resistance to PEM is associated with elevated activities of several
Externí odkaz:
https://doaj.org/article/ad934b0dab264311b72721325c553d40
Autor:
Takao Morinaga, Thảo Thi Thanh Nguyễn, Boya Zhong, Michiko Hanazono, Masato Shingyoji, Ikuo Sekine, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima, Masatoshi Tagawa
Publikováno v:
Virology Journal, Vol 14, Iss 1, Pp 1-10 (2017)
Abstract Background Genetically modified adenoviruses (Ad) with preferential replications in tumor cells have been examined for a possible clinical applicability as an anti-cancer agent. A simple method to detect viral and cellular proteins is valuab
Externí odkaz:
https://doaj.org/article/174d5b8dd5d84b5091fb4d01f2ff172a
Autor:
Suguru Yamauchi, Boya Zhong, Kiyoko Kawamura, Shan Yang, Shuji Kubo, Masato Shingyoji, Ikuo Sekine, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima, Masatoshi Tagawa
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-12 (2017)
Abstract Background Replication-competent adenoviruses (Ad) produced cytotoxic effects on infected tumors and have been examined for the clinical applicability. A biomarkers to predict the cytotoxicity is valuable in a clinical setting. Methods We co
Externí odkaz:
https://doaj.org/article/bfb496541896457c988a95250ffdedba