Zobrazeno 1 - 10
of 337
pro vyhledávání: '"Ikuo Miura"'
Autor:
Chad Schimek, Foyez Shams, Ikuo Miura, Simon Clulow, Zuzana Majtanova, Janine Deakin, Tariq Ezaz
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Amphibians have highly diverse sex-determining modes leading to a notable interest in vertebrate sex determination and sex chromosome evolution. The identification of sex-determining systems in amphibians, however, is often difficult as a va
Externí odkaz:
https://doaj.org/article/98c6010eaefc483aa5661e95e6c451f6
Publikováno v:
DNA, Vol 2, Iss 3, Pp 172-184 (2022)
The Y or W sex chromosome of a heteromorphic pair is usually heterochromatinised and degenerated. However, whether chromosome degeneration constantly proceeds toward an extreme end is not fully understood. Here, we present a case of intermittent evol
Externí odkaz:
https://doaj.org/article/86414cfac34f453584324e546b63b021
Autor:
Daniel L. Jeffries, Guillaume Lavanchy, Roberto Sermier, Michael J. Sredl, Ikuo Miura, Amaël Borzée, Lisa N. Barrow, Daniele Canestrelli, Pierre-André Crochet, Christophe Dufresnes, Jinzhong Fu, Wen-Juan Ma, Constantino Macías Garcia, Karim Ghali, Alfredo G. Nicieza, Ryan P. O’Donnell, Nicolas Rodrigues, Antonio Romano, Íñigo Martínez-Solano, Ilona Stepanyan, Silvia Zumbach, Alan Brelsford, Nicolas Perrin
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
The evolutionary forces that favour transitions in sex chromosomes are not well understood. Here, Jeffries and colleagues show a very high rate of sex chromosome turnover in true frogs, which may be driven by rapid mutation-load accumulation due to t
Externí odkaz:
https://doaj.org/article/ea6975326f4c4e69bec623473f15ebc8
Autor:
Tamio Furuse, Hiroshi Mizuma, Yuuki Hirose, Tomoko Kushida, Ikuko Yamada, Ikuo Miura, Hiroshi Masuya, Hiromasa Funato, Masashi Yanagisawa, Hirotaka Onoe, Shigeharu Wakana
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 9 (2019)
Dysfunction of glucose transporter 1 (GLUT1) proteins causes infantile epilepsy, which is designated as a GLUT1 deficiency syndrome (GLUT1DS; OMIM #606777). Patients with GLUT1DS display varied clinical phenotypes, such as infantile seizures, ataxia,
Externí odkaz:
https://doaj.org/article/cc49a2714ee7442fb81f77b38aa7c057
Autor:
Akiko Uchida, Yasushi Isobe, Junko Asano, Yu Uemura, Masahiro Hoshikawa, Masayuki Takagi, Ikuo Miura
Publikováno v:
Haematologica, Vol 104, Iss 7 (2019)
The so-called “double-hit” and “double-protein-expression” lymphoma with MYC and BCL2 rearrangements is a rare, mature B-cell neoplasm characterized by a germinal center B-cell phenotype, abundant protein expression of MYC and BCL2, rapid dis
Externí odkaz:
https://doaj.org/article/c81c92035be748a2aebbd4e5d2147188
Autor:
Ikuo Miura, Foyez Shams, Si-Min Lin, Marcelo de Bello Cioffi, Thomas Liehr, Ahmed Al-Rikabi, Chiao Kuwana, Kornsorn Srikulnath, Yuya Higaki, Tariq Ezaz
Publikováno v:
Cells, Vol 10, Iss 3, p 661 (2021)
Translocation between sex-chromosomes and autosomes generates multiple sex-chromosome systems. It happens unexpectedly, and therefore, the evolutionary meaning is not clear. The current study shows a multiple sex chromosome system comprising three di
Externí odkaz:
https://doaj.org/article/0c6ae99056ca49faaf275d02fb07d91f
Autor:
Yukari Nagai, Toshio Doi, Kunio Ito, Yoshiaki Yuasa, Takeshi Fujitani, Jun-ichi Naito, Mitsuaki Ogata, Ikuo Miura
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
The Nagoya Daruma pond frog Pelophylax porosus brevipodus is distributed in western Japan and is traditionally divided into two local forms: the Okayama form in the west and the Nagoya form in the east. These two forms are genetically differentiated,
Externí odkaz:
https://doaj.org/article/d4d3b65ff77543589ca41214930b9cc4
Autor:
Kazuhiro Okumura, Megumi Saito, Eriko Isogai, Ikuo Miura, Shigeharu Wakana, Ryo Kominami, Yuichi Wakabayashi
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97201 (2014)
Genome-wide association studies have revealed that many low-penetrance cancer susceptibility loci are located throughout the genome; however, a very limited number of genes have been identified so far. Using a forward genetics approach to map such lo
Externí odkaz:
https://doaj.org/article/ff5384b94a8949348963da849b1190d2
Autor:
Saiko Kurosawa, Shuichi Miyawaki, Takuhiro Yamaguchi, Heiwa Kanamori, Toru Sakura, Yukiyoshi Moriuchi, Fumiaki Sano, Takeshi Kobayashi, Atsushi Yasumoto, Kazuo Hatanaka, Masamitsu Yanada, Yuichiro Nawa, Jin Takeuchi, Yukinori Nakamura, Shin Fujisawa, Hirohiko Shibayama, Ikuo Miura, Takahiro Fukuda
Publikováno v:
Haematologica, Vol 98, Iss 10 (2013)
Core binding factor acute myeloid leukemia is known to have a favorable prognosis, however, there have been no detailed analyses on prognostic factors after first relapse. Using a nationwide database, we retrospectively analyzed core binding factor a
Externí odkaz:
https://doaj.org/article/4fce2915197c4bc7b218045aed1ad13a
Autor:
Saiko Kurosawa, Takuhiro Yamaguchi, Shuichi Miyawaki, Naoyuki Uchida, Toru Sakura, Heiwa Kanamori, Kensuke Usuki, Takuya Yamashita, Yasushi Okoshi, Hirohiko Shibayama, Hirohisa Nakamae, Momoko Mawatari, Kazuo Hatanaka, Kazutaka Sunami, Manabu Shimoyama, Naohito Fujishima, Yoshinobu Maeda, Ikuo Miura, Yoichi Takaue, Takahiro Fukuda
Publikováno v:
Haematologica, Vol 95, Iss 11 (2010)
Background Patients with acute myeloid leukemia who are treated with conventional chemotherapy still have a substantial risk of relapse; the prognostic factors and optimal treatments after relapse have not been fully established. We, therefore, retro
Externí odkaz:
https://doaj.org/article/2b4b19720230449bba867998468f4a6d