Zobrazeno 1 - 10
of 299
pro vyhledávání: '"Ikuo Kimura"'
Autor:
Akari Nishida, Ryuji Ohue‐Kitano, Yuki Masujima, Hazuki Nonaka, Miki Igarashi, Takako Ikeda, Ikuo Kimura
Publikováno v:
FASEB BioAdvances, Vol 6, Iss 11, Pp 526-538 (2024)
Abstract Overconsumption of food, especially dietary fat, leads to metabolic disorders such as obesity and type 2 diabetes. Long‐chain fatty acids, such as palmitoleate are recognized as the risk factors for these disorders owing to their high‐en
Externí odkaz:
https://doaj.org/article/fec1af18252a417ab49bab489283c4b9
Autor:
Jun Kambe, Kento Usuda, Ryo Inoue, Kazuhiko Hirayama, Masahiko Ito, Ken Suenaga, Sora Masukado, Hong Liu, Shiho Miyata, Chunmei Li, Ikuo Kimura, Yuki Yamamoto, Kentaro Nagaoka
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Early life environment influences mammalian brain development, a growing area of research within the Developmental Origins of Health and Disease framework, necessitating a deeper understanding of early life factors on children’s brain development.
Externí odkaz:
https://doaj.org/article/97b034426dfd4aa1b5465c77e273e317
Gut microbial metabolites reveal diet-dependent metabolic changes induced by nicotine administration
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The gut microbiota has emerged as an important factor that potentially influences various physiological functions and pathophysiological processes such as obesity and type 2 diabetes mellitus. Accumulating evidence from human and animal stud
Externí odkaz:
https://doaj.org/article/19a79c5871dc4eb59a10870f0e863b13
Autor:
Ryuji Ohue-Kitano, Yuki Masujima, Shota Nishikawa, Masayo Iwasa, Yosuke Nishitani, Hideaki Kawakami, Hiroshige Kuwahara, Ikuo Kimura
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract 3-(4-hydroxy-3-methoxyphenyl) propionic acid (HMPA) is a metabolite produced by the gut microbiota through the conversion of 4-hydroxy-3-methoxycinnamic acid (HMCA), which is a widely distributed hydroxycinnamic acid-derived metabolite found
Externí odkaz:
https://doaj.org/article/d915d09b8d3a4c1ab1a2240a4e61ba6a
Autor:
Minami Nagai, Miyu Moriyama, Chiharu Ishii, Hirotake Mori, Hikaru Watanabe, Taku Nakahara, Takuji Yamada, Dai Ishikawa, Takamasa Ishikawa, Akiyoshi Hirayama, Ikuo Kimura, Akihito Nagahara, Toshio Naito, Shinji Fukuda, Takeshi Ichinohe
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Fever is a common symptom of influenza and coronavirus disease 2019 (COVID-19), yet its physiological role in host resistance to viral infection remains less clear. Here, we demonstrate that exposure of mice to the high ambient temperature o
Externí odkaz:
https://doaj.org/article/751754dc12254778afd6f740e9152c9e
Autor:
Takashi Ito, Yumiko Nakanishi, Ryohei Shibata, Noriko Sato, Toshi Jinnohara, Sayo Suzuki, Wataru Suda, Masahira Hattori, Ikuo Kimura, Taiji Nakano, Fumiya Yamaide, Naoki Shimojo, Hiroshi Ohno
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTEvidence has accumulated that gut microbiota and its metabolites, in particular the short-chain fatty acid propionate, are significant contributors to the pathogenesis of a variety of diseases. However, little is known regarding its impact on
Externí odkaz:
https://doaj.org/article/e6105ea5b3404f5d839b78170f63b630
Autor:
Junki Miyamoto, Hidenori Shimizu, Keiko Hisa, Chiaki Matsuzaki, Shinsuke Inuki, Yuna Ando, Akari Nishida, Ayano Izumi, Mayu Yamano, Chihiro Ushiroda, Junichiro Irie, Takane Katayama, Hiroaki Ohno, Hiroshi Itoh, Kenji Yamamoto, Ikuo Kimura
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTFermented foods demonstrate remarkable health benefits owing to probiotic bacteria or microproducts produced via bacterial fermentation. Fermented foods are produced by the fermentative action of several lactic acid bacteria, including Leucon
Externí odkaz:
https://doaj.org/article/863ae83d61be4aebbe7696fd3bdeac9a
Publikováno v:
Brain Sciences, Vol 14, Iss 3, p 197 (2024)
In recent years, neurorehabilitation has been actively used to treat motor paralysis after stroke. However, the impacts of rehabilitation on neural networks in the brain remain largely unknown. Therefore, we investigated changes in structural neural
Externí odkaz:
https://doaj.org/article/4e6bb9d21aab4ca1b8d4c40c94a08913
Autor:
Fukie Yaoita, Keita Watanabe, Ikuo Kimura, Masayuki Miyazawa, Shinobu Tsuchiya, Makoto Kanzaki, Masahiro Tsuchiya, Koichi Tan-No
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract The gut environment, including the microbiota and its metabolites and short-chain fatty acids (SCFA), is essential for health maintenance. It is considered that functional recovery treatment for masticatory dysphagia affects the composition
Externí odkaz:
https://doaj.org/article/e1ece55eea204ad6a98b4bffc137d6a2
Autor:
Ryuji Ohue-Kitano, Hazuki Nonaka, Akari Nishida, Yuki Masujima, Daisuke Takahashi, Takako Ikeda, Akiharu Uwamizu, Miyako Tanaka, Motoyuki Kohjima, Miki Igarashi, Hironori Katoh, Tomohiro Tanaka, Asuka Inoue, Takayoshi Suganami, Koji Hase, Yoshihiro Ogawa, Junken Aoki, Ikuo Kimura
Publikováno v:
JCI Insight, Vol 8, Iss 2 (2023)
Medium-chain triglycerides (MCTs), which consist of medium-chain fatty acids (MCFAs), are unique forms of dietary fat with various health benefits. G protein–coupled 84 (GPR84) acts as a receptor for MCFAs (especially C10:0 and C12:0); however, GPR
Externí odkaz:
https://doaj.org/article/ecafa7ca37954e389e6d0e6f51ad1a89